Company

About

A-Alpha Bio

A-Alpha Bio

Seattle, Washington, United States

A-Alpha Bio is a biotechnology company harnessing synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions. Our experimental platform, AlphaSeq, enables the rapid and quantitative measurement of millions of protein-protein binding affinities simultaneously. Our computational platform, AlphaBind, is trained on the world’s largest protein-protein interaction database and predicts binding strength from sequence. A-Alpha Bio leverages AlphaSeq and AlphaBind for in-house therapeutic programs and in partnership with leading pharmaceutical companies to inform the discovery and development of novel therapeutics. A-Alpha Bio is based in Seattle and was founded in 2017 at the University of Washington's Institute for Protein Design and Center for Synthetic Biology. To learn more, please visit: https://www.aalphabio.com/

Abacus Bioscience

Abacus Bioscience

Seattle, Washington, United States

Abacus Bioscience is developing a new class of immunotherapy that unleashes the power of a novel CD180 platform technology. Our Antigen-Specific Immune Accelerants (ASIA) are POTENT, SPECIFIC and DURABLE, with broad applications across infectious disease and oncology.

Absci

Absci

Vancouver, Washington, United States

Absci is a generative AI drug creation company that combines AI with scalable wet lab technologies to create better biologics for patients, faster. Our Integrated Drug Creation™ platform unlocks the potential to accelerate time to clinic and increase the probability of success by simultaneously optimizing multiple drug characteristics important to both development and therapeutic benefit. With the data to learn, the AI to create, and the wet lab to validate, we can screen billions of cells per week, allowing us to go from AI-designed antibodies to wet lab-validated candidates in as little as six weeks. Our vision is to deliver breakthrough therapeutics at the click of a button, for everyone.

Absco Therapeutics

Absco Therapeutics

Vancouver, Washington, United States

Absco Therapeutics, Inc. (AbscoTx) is a stealth phase immune engineering company born out of collaborative work between clinicians at MGH and BWH, engineers at MIT, and an experienced team of biotech entrepreneurs and translational medicine experts.

Access to Advanced Health Institute (AAHI)

Access to Advanced Health Institute (AAHI)

Seattle, Washington, United States

Like it's predecessor, the Infectious Disease Reseach Institute (IDRI), the Access to Advanced Health Institute (AAHI) focuses on creating technologies that improve the body's response to disease.AAHI is a nonprofit biotech organization that works on a comprehensive approach to developing new solutions for infectious disease.

Achieve Life Sciences

Achieve Life Sciences

Seattle, Washington

Achieve Life Sciences is a specialty pharmaceutical company committed to advancing cytisine as a smoking cessation aid to overcome the global nicotine addiction epidemic.

Adaptive Biotechnologies Corporation

Adaptive Biotechnologies Corporation

Seattle, Washington, United States

Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases. The company offers immunoSEQ research service and kit that is used to answer research questions, as well as to discover new prognostic and diagnostic signals. It also provides clonoSEQ diagnostic tests, which include immunosequencing services for use in the detection and monitoring of minimal residual disease in patients with select blood cancers. In addition, the company offers a pipeline of clinical products and services that are used for the diagnosing, monitoring, and treatment of diseases, such as cancer, autoimmune conditions, and infectious diseases. Adaptive Biotechnologies Corporation has strategic collaborations with Genentech, Inc. for the development, manufacture, and commercialization of neoantigen directed T cell therapies for the treatment of a range of cancers; Microsoft Corporation to develop diagnostic tests for the early detection of various diseases from a single blood test; and Amgen to develop a therapeutic to prevent or treat COVID-19. It serves the life sciences research, clinical diagnostics, and drug discovery customers. Adaptive Biotechnologies Corporation has a translational collaboration with AstraZeneca to investigate the use of immunoSEQ T-MAP. The company was formerly known as Adaptive TCR Corporation and changed its name to Adaptive Biotechnologies Corporation in December 2011. Adaptive Biotechnologies Corporation was founded in 2009 and is headquartered in Seattle, Washington.

Algomedix

Algomedix

Mill Creek, Washington, United States

Algomedix is an emerging biotechnology company which is using the advances in precision medicine to accelerate drug discovery and development for TRP (Transient Receptor Potential) targeted therapeutics. Critical members of the large TRP superfamily include TRPA1, which is a validated target recognized by the pharmaceutical industry for the discovery and development of novel therapeutics to treat pain, inflammation, ocular and dermatological disease. Algomedix has successfully identified novel small molecules that target human TRPA1 with both high potency and specificity, and have been optimized to have excellent drug-like properties. Thus, the Algomedix compounds represent a major advance in next-generation pain killers which have no opioid related, NSAID related, or gabapentanoid adverse effects, and have been rationally designed to have no addiction or abuse liabilities. These advantages are further enhanced by a primary peripheral mechanism of action, blocking pain at its source. Algomedix possesses near-term clinical development opportunities combined with novel approaches to developing its first-in-class novel therapeutics addressing a critical unmet medical need. Algomedix's most advanced patented compound is in late-stage preclinical development and prepared to advance to clinical trials. This compound has demonstrated potent analgesic activity activity in multiple established pain models, which are recognized as the gold standards in the areas of osteoarthritis pain (OA), neuropathic pain, and chemotherapeutic-induced peripheral neuropathy. Due to the critical and fundamental role of TRPA1 in mediating the initial steps of pain signaling throughout the body, there are multiple therapeutic applications for treating chronic and acute pain in patients. In addition, Algomedix is pursuing programs developing a pipeline of novel, first-in-class molecules for other indications, which include chronic kidney disease and cardiac hypertrophy

Allen Institute

Allen Institute

615 Westlake Ave N, Seattle, Washington 98109, US

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science. Founded by philanthropist and visionary Paul G. Allen, the Allen Institute is a recognized leader in large-scale, open science research. Its research institutes include the Allen Institute for Brain Science, Allen Institute for Cell Science, Allen Institute for Immunology and The Paul G. Allen Frontiers Group. The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for our open positions.

Alli Connect

Alli Connect

Seattle, Washington, United States

Alli Connect is a mental health care service for first responders that proactively promotes wellness and positive change in public safety.

Allysta Pharmaceuticals

Allysta Pharmaceuticals

Bellevue, WA

Allysta Pharmaceuticals is a private venture-backed clinical stage biopharmaceutical focused on rare diseases with high unmet needs. We are developing first-in-class therapeutic peptides with multiple biological actions, including anti-fibrotic, anti-inflammatory, cell regenerative, and beneficial metabolic effects that provides development opportunities across multiple diseases. Our lead drug, ALY688ER, an extended release formulation designed for extended delivery of ALY688 throughout the body, is a potent and specific activator of adiponectin signaling pathways. Adiponectin is a beneficial cytokine produced mainly by adipose cells and which protects against obesity-associated diseases. ALY688 is the first adiponectin receptor agonist to enter human testing. Our lead indication is Duchenne muscular dystrophy (DMD), a serious rare genetic disease of boys in which muscle tissue damage due to muscle cell injury, inflammation and replacement of muscle by fibrotic tissue results in progressive loss of skeletal muscle function. In relevant animal DMD models, ALY688 reduced muscle cell death, enhanced muscle regeneration, and reduced inflammation and fibrosis, resulting in preservation of muscle strength and endurance. In addition, ALY688 has shown similar benefits across a range of other inflammatory and fibrotic conditions potentially expanding its use in additional indications.

Altius

Altius

Seattle, Washington, United States

Altius Institute for Biomedical Sciences is an independent, nonprofit research organization created to pursue discovery at the leading edge of modern biomedicine. Enabled by a visionary founding investment from GlaxoSmithKline, Altius is creating a new paradigm to catalyze ground-breaking biological innovation, integrate molecular and computational science and engineering, and empower fundamental technology development to radically accelerate the leap from basic to medical breakthroughs. Altius is pioneering a new framework for conceiving, executing and sharing rapidly-moving science by replacing traditional hierarchies and silos with a networked organization that maximizes discovery through synergy. We are now expanding our team of talented computational scientists with experience in machine learning, data visualization and information design. In addition, we are looking for outstanding postdoctoral researchers with - computational and/or experimental - experience in genomics research. These Altius Fellows will be provided with exceptional resources, operational and salary support, and mentorship to pursue groundbreaking interdisciplinary research at the leading edge of genome biology.

AltPep

AltPep

Seattle, Washington

AltPep develops early disease-modifying treatments and detection tools for amyloid diseases by targeting one of the earliest molecular triggers – toxic soluble oligomers. These oligomers are associated with many diseases, including neurodegenerative diseases and type 2 diabetes. Decades of scientific research by the Daggett Research Group culminated in the discovery of a novel protein structure, alpha-sheet, the foundation of our innovative approach. Our lead program aims to identify Alzheimer’s Disease long before symptoms occur and then neutralize the toxic soluble oligomers associated with the disease.

Aptevo Therapeutics

Aptevo Therapeutics

Seattle, Washington, United States of America

Aptevo Therapeutics is a biotech company primarily focused on bringing novel oncology and hematology therapeutics to market. We leverage the innovative ADAPTIR™ platform technology, a unique approach to cancer immunotherapy, to improve outcomes for cancer patients. Based in Seattle, Washington, the company is proud of its empowering work environment, entrepreneurial culture, and proprietary platform technology. As a result, Aptevo has been able to attract some of the most innovative minds in the field. Many of our team members have notable experience with other pioneering biotech companies including Trubion, ZymoGenetics, Immunex, Dendreon, and VLST.

Arbele

Arbele

Bellevue, Washington, United States

Arbele is a locally grown pharmaceutical biotech focused on immunotherapy of cancers, immune disorders and neurological diseases. The company founding team has a strong combination of business development and pharmaceutical R&D, with an accumulation of >30 year experience in multinational drug companies. Our motto is to excel patient healthcare through innovation and breakthrough. Our mission is to deliver innovative and cost-effective therapeutics to treat diseases of unmet needs. We focus on antibody-based therapeutic platforms, including chimeric antigen receptor (CAR)-T and Bi-specific antibody technology, while leveraging new technology on CRISPR genome editing. Our culture ingredients are “integrity and social values”.

Archon Biosciences

Archon Biosciences

Seattle, WA

Archon is a biotechnology company developing computationally designed proteins to unlock powerful therapeutic targets that lie beyond the reach of existing modalities and to better treat disease. We directly apply generative protein design to create a new biologic class, Antibody Cages (AbCs), that integrates the industry-proven affinity and specificity of antibodies into self-assembling nanostructures. Precise control over AbC structure provides the ability to tune both how they distribute in the body and engage their cellular targets with high specificity and potency to establish a new gold-standard for biologic medicines.

Athira Pharma

Athira Pharma

Bothell, Washington, United States of America

At Athira, we aim to restore neuronal health for those suffering from neurological diseases, including Alzheimer’s, so that patients can regain their memories, lives, and family relationships.

Atossa Therapeutics

Atossa Therapeutics

Seattle, Washington, United States of America

Atossa Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines in the areas of oncology and infectious diseases. The company’s lead program is Endoxifen, an active metabolite of tamoxifen, which is in Phase II clinical trials to treat and prevent breast cancer. It is also developing AT-301, a proprietary drug candidate for nasal administration in patients diagnosed with COVID-19; AT-H201, a drug candidate to improve lung function in COVID-19 patients; and immunotherapy/chimeric antigen receptor therapy programs for the treatment of breast cancer. Atossa Therapeutics, Inc. has a research agreement with Dana-Farber Cancer Institute, Inc. to support research of cytokine-coated nanoparticles for the potential treatment of breast cancer. The company was formerly known as Atossa Genetics Inc. and changed its name to Atossa Therapeutics, Inc. in January 2020. Atossa Therapeutics, Inc. was founded in 2008 and is headquartered in Seattle, Washington.

Aurion Biotechnologies

Aurion Biotechnologies

Seattle, Washington, United States

Aurion Biotech is a clinical stage biotech company, developing a transformational platform of advanced therapies to cure blindness. Our first candidate is for the treatment of corneal endothelial disease, and one of the first clinically validated cell therapies for corneal care.

Avalyn Pharma

Avalyn Pharma

Seattle, Washington, United States

Avalyn is a clinical-stage biopharmaceutical company developing inhaled therapies to treat rare respiratory diseases, including idiopathic pulmonary fibrosis and other interstitial lung diseases. Our lead candidate, AP01, is a Phase 2b-ready inhaled formulation of pirfenidone in development for the treatment of pulmonary fibrosis

AVM Biotechnology

AVM Biotechnology

Seattle, Washington, United States

AVM is a clinical-stage biotech company located in Seattle WA led by Dr. Theresa Deisher, a biotech veteran with a productive history including 47 patents and 4 discoveries in clinical trials. The company's lead drug AVM0703, an innovative formulation of dexamethasone, when given at suprapharmacologic doses has a novel mechanism of action to mobilize the body's own natural supercharged immune cells. AVM0703 triggers the production and release of endogenous gamma delta+ Natural Killer T cells and could be the first choice for no-option cancer, autoimmunity, and infectious disease. AVM Biotechnology has a Scientific Advisory Board including well-respected leaders in cancer and immunology. The company is committed to developing products that improve outcomes without additional suffering because side effects from treatments should never be worse than the diseases themselves.

BioViva USA Inc

BioViva USA Inc

Bainbridge Island, Washington, United States

BioViva USA is dedicated to improving healthy human longevity through bioinformatics. The Biovault bioinformatics platform is contributing to health predictions and recommendations, precision medicine, and the discovery of novel biomarkers by applying state of the art computational methods on vastcollections of biological data.BioViva is partnered with Integrated Health Systems (IHS). IHS is an innovative company specializing in cell and gene therapy, aprivate care company supporting health professionals working with groundbreaking treatments and therapeutics to support healthy longevity. Theywork exclusively with regenerative medicine specialists targeting the aging process.BioViva is committed to:Bridging stakeholders with biotechnologyFacilitating the development of treatments and therapeutics through the BioViva platform, designed to be readily browsable by longevity researchers.Accelerating the path to human trials for life-saving gene therapies.Providing biotechnology companies, medical researchers, and patients access to one another, expediting research and development.The Biovault will continuously update user profiles, including changes in relevant biomarkers. BioViva is utilizing the latest machine learning algorithms to formulate hypotheses and validate findings, thereby paving the way for optimal combinatorial regimens addressing the root causes of the aging process.

Blaze Bioscience

Blaze Bioscience

Seattle, Washington, United States

Blaze Bioscience, Inc. is a privately held biotechnology company dedicated to improving the lives of cancer patients, starting with kids undergoing brain cancer surgery. By leveraging our Tumor Paint technology®, including the CANVAS Imaging system® and our CDP Discovery Platform, our goal is to make the detection, removal, and treatment of all cancers sensitive, reliable, and accessible, especially early-stage cancers where cure may still be possible.

Bloodworks Northwest

Bloodworks Northwest

921 Terry Avenue, Seattle, Washington 98104, US

Bloodworks Northwest is an independent, community-based nonprofit organization with a tradition blending volunteerism, medical science, education and research to advance transfusion medicine and improve patient care. A recognized leader in transfusion medicine, Bloodworks serves patients in nearly 90 hospitals and clinics in the Pacific Northwest and provides tissue and transplantation support to 185 hospitals across the Northwest. Patients with leukemia, cancer, burns, hemophilia and traumatic injuries also depend on Bloodworks research. With your help, we're bettering our community drop by drop.

Bonum Therapeutics

Bonum Therapeutics

Seattle, Washington, United States

Bonum Therapeutics is focused on a proven technology that utilizes allosteric regulation to create targeted, highly active, and less toxic medicines.

BrainChild Bio

BrainChild Bio

1920 terry avenue, seattle, wa, united states

We are a kids-first, clinical-stage biotechnology company focused on harnessing the power of CAR-T cell technology for tumors n the central nervous system (CNS), prioritizing pediatrics with plans to expand our technology to adult indications. We are building a platform to optimize the application of CAR-T technology in CNS tumors-- prioritizing diffuse intrinsic pontine glioma (DIPG) with plans to expand to other pediatric and adult brain tumors, including brain metastases.

Cadence Neuroscience Inc.

Cadence Neuroscience Inc.

8201 164th Ave NE, Suite 330, Redmond, WA 98052, US

Cadence Neuroscience is developing a fundamentally new approach to neuromodulation, starting with a therapy to treate severe epilepsy.

Callio Therapeutics

Callio Therapeutics

Seattle, US

Cancer Targeted Technology

Cancer Targeted Technology

Woodinville, Washington, United States

CancerTargetedTechnology develops innovative agents for cancer that accurately detect early and advanced disease, monitor treatment efficacy

Capsigen

Capsigen

Vancouver, Washington, United States

Capsigen is a leader in the engineering of AAV capsids for use in gene therapies, opening the path to permanent cures for patients suffering from intractable illness. Capsigen is enabling a new era of genetic medicines based on a disease-first approach. Powered by our TRADE™ and data science platforms, we engineer vectors with the highest possible potency and cell-type specificity. Developing genetic medicines that are tailored to the unique biology involved in the disease ensures that the therapy can bring the maximum benefit to patients. Our team is driven in its pursuit to deliver on this promise to the millions of people depending on the advancement of science to discover new cures.

Cascadia Drug Development Group

Cascadia Drug Development Group

Seattle, Washington, United States

The Cascadia Drug Development Group was founded by seasoned industry experts who are passionate about immunology and drug development. CDDG provides strategic advisory support, including indication prioritization and investment opportunity diligence, as well as planning and tactical oversight of therapeutic development activities. Importantly, we help integrate quality decisions into programs early and focus on efficiently bridging the gap between discovery, lead generation and initial clinical proof of concept. By offering a flexible and virtual structure and leveraging an externalized research model, we easily adapt to client and project needs to reduce overall costs. Our aspiration is to provide the highest quality approach to drug development that maximizes the value of excellent therapeutic opportunities around the globe.

Cerevast Medical, Inc.

Cerevast Medical, Inc.

Bothell, Washington, United States

Founded in 2015, Cerevast Medical, Inc. is a clinical-stage medical device company based in Bothell, Washington, USA. Leveraging our core expertise in the fields of ultrasound and microsphere technologies, we are committed to developing novel, first-in-class therapeutic solutions to restore health and improve the quality of life for patients that suffer from major diseases.

Cisthera

Cisthera

Redmond, WA

CisThera Inc. is a privately owned biopharmaceutical company in the Seattle area. CisThera’s mission is to develop innovative therapeutics to treat cancer, autoimmune diseases, as well as chronic kidney and liver diseases. CisThera is taking a novel approach to identify drugs with greater efficacy that broadly inhibit validated contributors to disease pathogenesis.

Cocrystal Pharma

Cocrystal Pharma

Bothell, Washington, United States of America

Cocrystal Pharma, Inc. is a clinical stage biotechnology company seeking to discover and develop novel antiviral therapeutics as treatments for serious and/or chronic viral diseases. We employ unique structure-based technologies and Nobel Prize winning expertise to create first- and best-in-class antiviral drugs. These technologies are designed to efficiently deliver small molecule therapeutics that are safe, effective, and convenient to administer. We have identified promising preclinical and early clinical stage antiviral therapeutics that target the replication process of influenza virus, SARS-CoV-2 virus, hepatitis C virus, and norovirus.

Compliment Corporation

Compliment Corporation

Seattle, Washington, United States

Compliment Corporationis a start-up biotechnology company developing revolutionary therapeutics in oncology. Ourmission is to improve cancer treatment by dramatically increasing the effectiveness of cancer drugs and by reducing the toxicities associated with standard chemotherapy treatment.

Conjustar

Conjustar

901 Fifth Avenue, Suite 1200, Seattle, WA 98164

Tianjin Conjustar Biotechnology Co., Ltd. is a researcher and developer of peptide-drug conjugate intended for oncology treatments. The company was established in early 2022 and is located in Tianjin Airport Free Trade Zone. It was founded by Fosun Health Capital and focuses on cooperative development and independent research.

Curevo Vaccine

Curevo Vaccine

Bothell, Washington, United States

Curevo will combine excellence in protein science and adjuvant technology to speed safe and highly effective vaccines from the bench through clinical development. Curevo will focus on vaccine-preventable illnesses that are common in both the Asian and US markets and for which current vaccine products are not available. Cuervo's goal is to rapidly advance innovative new vaccine candidates from the research laboratory to the clinic by joining forces with the South Korean Mogam Institute for Biomedical Research, GC Pharma, and the Infectious Disease Research Institute based in Seattle, Washington.

CytoDyn Inc

CytoDyn Inc

Vancouver, Washington, United States of America

CytoDyn Inc., a late-stage biotechnology company, focuses on the clinical development and commercialization of humanized monoclonal antibodies to treat human immunodeficiency virus (HIV) infection. Its lead product is PRO 140, a therapeutic anti-viral agent, which is in Phase IIb extension study for HIV as monotherapy, rollover study for HIV as a combination therapy, Phase IIb/III investigative trial for HIV, Phase Ib/II trial for triple-negative breast cancer, and Phase II trial for graft-versus-host disease. CytoDyn Inc. has strategic agreement with Samsung BioLogics Co. Ltd. for the clinical and commercial manufacturing of leronlimab. The company was formerly known as RexRay Corporation. CytoDyn Inc. was incorporated in 2002 and is based in Vancouver, Washington.

Deverra Therapeutics

Deverra Therapeutics

Seattle, Washington, United States

Deverra Therapeutics is a clinical stage biotechnology company dedicated to the development of allogeneic, off-the-shelf cellular immunotherapies for on-demand treatment of patients with cancer and infectious diseases. The company has an exclusive license to a proprietary stem cell expansion and directed-differentiation platform from the Fred Hutchinson Cancer Research Center based on more than 20 years of federally funded research and data from 5 clinical trials. This platform can be used to generate a range of unmodified and modified immune cells to treat patients with cancer and infectious diseases.

Eliem Therapeutics

Eliem Therapeutics

Bellevue, Washington, United States of America

Eliem Therapeutics, Inc. is a clinical stage biotechnology company focused on developing therapies for neuronal excitability disorders with the goal of restoring balance in both the peripheral and central nervous systems to help patients live on their own terms. Eliem channels its experience, energy, and passion for improving patients’ quality of life by developing life-changing novel therapies for disorders such as chronic pain, depression, epilepsy, focal onset seizures, and anxiety – conditions that make simple daily activities challenging for impacted patients.

EMulate Therapeutics

EMulate Therapeutics

Seattle, Washington, United States

Founded in 2002 and headquartered in Seattle, WA, EMulate Therapeutics is a clinical-stage therapeutic device company. EMulate Therapeutics has invented and patented a groundbreaking technology that utilizes precisely targeted, ultra-low radio frequency energy (ulRFE®) to specifically regulate signaling and metabolic pathways on the molecular and genetic levels – without chemicals, radiation or drugs – delivered via a simple-to-use non-invasive device called EMulate Therapeutics Voyager. The company's goal is to transform disease treatment on a global scale with ulRFE®. The proprietary technology has the potential to be applied to a wide range of conditions as well as veterinary medicine and non-medical applications. EMulate Therapeutics' initial focus is on the treatment of patients with brain cancer who are not well served by conventional standard of care therapies, which often result in poor outcomes and devastating side effects. Additional pre-clinical work is focused on exploring new applications in oncology and pain treatment.

Faraday Pharmaceuticals

Faraday Pharmaceuticals

Seattle, Washington, United States

At Faraday Pharmaceuticals, Inc., our mission is to improve quality of life for patients after acute critical illness by minimizing damage to cardiac and skeletal muscle.

FenoLogica Biosciences

FenoLogica Biosciences

Seattle, Washington, United States

FenoLogicahelpsscientists gain insight into complex cellular interactions, creating a deeper understanding of human disease to improve patient outcomes. Our combined instrumentation and Cloud-based quantitative biology tools expedite the understanding of disease susceptibility and causation, leading to optimized therapeutic solutions.

Fred Hutch

Fred Hutch

Seattle, Washington, United States

Fred Hutch is an independent, nonprofit organization that also serves as the cancer program for UW Medicine. Together we provide the specialized focus of a top-ranked cancer center and the comprehensive services of a leading integrated health system.

Geneva Foundation

Geneva Foundation

Tacoma, Washington, United States

The Geneva Foundation is a 501(c)3 nonprofit established in 1993 with the purpose to ensure optimal health for service members and the communities they serve. This purpose is accomplished through our mission to advance military medicine through research, development, and education. Geneva has 30 years of experience in delivering full spectrum scientific, technical, and program management expertise in the areas of federal grants, federal contracts, industry sponsored clinical trials, and educational services.

Halo-Bio RNAi Therapeutics, Inc.

Halo-Bio RNAi Therapeutics, Inc.

Seattle, Washington, United States

Multivalent RNAi Platform, Delivery

HDT Bio

HDT Bio

Seattle, Washington, United States

HDT Bio is a vaccine and immunotherapy Biotechnology company developing drugs for immunotherapy of cancers and infectious diseases with next-generation approaches designed to enable the body’s immune system to prevent and cure disease. We have engineered our technologies to Access, Activate, and Amplify the immune system’s natural ability to create antibodies and T-cells that fight cancer and infectious diseases such as SARS-CoV-2. We are developing multiple product candidates from our proprietary discovery platforms, including LION™, which has the potential to provide health benefits to a broad patient population. Our products are designed to be cost-effective solutions to unmet medical needs and complementary to existing, cutting-edge immunotherapies. HDT Bio offers a comprehensive compensation plan which includes health insurance for employees and dependents (inclusive of multiple plants to choose from, including a $0 premium plan with HSA and company contribution), generous PTO (11 observed holidays and week long year-end closure), stock options with Carta Tax Advisory for equity and tax support, flexible spending accounts (FSAs), commuting benefits (ORCA or paid parking), and retirement benefits with company match. HDT Bio Corp. is an equal opportunity employer committed to a diverse and inclusive workforce. This environment is encouraged by HDT's culture, which supports women in science through our Women+ group, creates inclusive events to highlight the diverse cultures represented by our staff, and with the adoption of an open office environment for all.

Helix BioMedix

Helix BioMedix

Bothell, WA

Helix BioMedix develops bioactive peptides based on specific natural cellular sequences for targeted topical efficacy. Our extensive library of proprietary peptide sequences can be used to treat a growing range of dermatological conditions including acne, rosacea, fungus and MRSA. Our mission is to enrich clinical practice and patient/consumer well being by developing topically-applied products which offer the health, beauty and safety benefits of our advanced bioactive small molecule peptide technology.

Histone Therapeutics

Histone Therapeutics

Seattle, WA 98118, US

Histone Therapeutics is a biotechnology company at the forefront of precision epigenetic reprogramming that is focused on enhancing cell function and treating disease by controlling gene regulation. Our team shares the conviction that new drug modalities based on protein modifiers of chromatin remodeling could provide new options for treating disease and enhancing the human condition.

Ice Bear Therapeutics

Ice Bear Therapeutics

Seattle, Washington, United States

Ice Bear Therapeutics SPC is a social purpose company based in Seattle, WA, founded 2021, with the mission of bringing affordable insulin to patients with type 1 or type 2 diabetes.

Immusoft

Immusoft

Seattle, Washington, United States

Immusoft is a cell therapy company focused on developing novel therapies for rare diseases using sustained delivery of therapeutic proteins from a patient’s own cells. The company is developing a technology platform called Immune System Programming (ISP™), which modifies a patient’s B cells and instructs them to produce gene-encoded medicines. The B cells that are reprogrammed using ISP become miniature drug factories that are expected to survive in patients and provide therapeutic benefit for many years. The company is based in Seattle, WA.

Impel Pharmaceuticals

Impel Pharmaceuticals

Seattle, Washington, United States

Impel NeuroPharma, Inc., a late-stage pharmaceutical company, focuses on the development and commercialization of therapies for patients suffering from central nervous system disease in the United States. Its lead product candidate is TRUDHESA, an upper nasal formulation of dihydroergotamine for the acute treatment of migraine. The company is also developing INP105, an upper nasal formulation of olanzapine for the acute treatment of agitation and aggression in autism spectrum disorder; and INP107, an upper nasal formulation of carbidopa/levodopa for the treatment of OFF episodes in Parkinson’s disease. Impel NeuroPharma, Inc. was incorporated in 2008 and is headquartered in Seattle, Washington.

InduPro

InduPro

Seattle, Washington

InduPro is a biotechnology company that brings proteins on the cell surface closer together, manipulating their interactions and opening new possibilities for treating various conditions.

Inipharm

Inipharm

Bellevue, Washington, United States

Inipharm is a biopharmaceutical company focused on discovering and developing therapies for severe liver diseases. Inipharm's lead program is focused on the highly validated, genetically-defined target, HSD17B13. There is extensive, consistent evidence that genetic variants in expression of HSD17B13 are associated with significantly lower rates and severity of multiple liver diseases. Building on these novel insights into the biologic activity of HSD17B13, Inipharm is advancing a pipeline of small-molecule therapies that target the activity of this protein.

Inmedix

Inmedix

Normandy Park, Washington, United States

Inmedixfocuses on autonomic nervous system (ANS) control of stress responses within the brain. In the setting of an autoimmune disease, ANS stress can significantly intensify an autoimmune disease. Inmedixcall’sit Immuno-autonomics. Theyseek to understand and block this process to allow current autoimmune disease therapies to work much better.

Institute for Disease Modeling (IDM)

Institute for Disease Modeling (IDM)

Bellevue, Washington, United States

The Institute for Disease Modeling (IDM) is part of the Bill & Melinda Gates Foundation's Global Health Division. IDM's goal is to support global efforts to eradicate infectious diseases and achieve permanent improvements in health by developing, using, and sharing computational modeling tools and promoting quantitative decision-making. Improving the health of all people, especially those in the most vulnerable populations, is a pressing and complex problem that engages diverse contributors, from health workers on the ground to funding agencies that provide resources and support. Data-driven approaches, including the development of dynamic models, statistical analysis, and the development and application of innovative algorithms, make fundamental contributions that inform primary research programs, intervention strategies, resource allocation, and other avenues of health care delivery.

Intrinsic Medicine

Intrinsic Medicine

Seattle, Washington, United States

Intrinsic Medicine is a preclinical-stage therapeutics company leveraging human-identical molecules as new medicines. Their initial drug candidates are based on bioactive oligosaccharides naturally produced in human milk, or HMOs, which directly modulate the immune system and other human cells as well as the gut microbiome

Inventprise

Inventprise

Redmond, Washington

By developing novel and affordable vaccines for all populations worldwide we're addressing health inequalities and empowering people to live healthy lives Inventprise is a mission driven vaccine manufacturing company developing vaccines that have shown a more robust and broader spectrum of protection than currently marketed conjugated vaccines. Our lead vaccine candidate is a 25-valent pneumococcal conjugate vaccine (PCV) funded by the Bill and Melinda Gates Foundation (>$100M) and aimed at large-scale supply to Low-Middle Income Countries. Additionally, we have a robust pipeline of vaccines and vaccine technologies, that have both viral and bacterial applications. Inventprise was founded in 2012, and is led by founder and Executive Chairman, Subhash Kapre PhD, former SVP and Corporate Officer of Serum Institute of India and Chief Executive Officer, Yves Leurquin, former general manager of Takeda Vaccines, Europe. Inventprise is based in Redmond, Washington, we have over 100,000 square feet of recently built, state-of-the-art facilities that have the capacity for large scale volume (>150M annual doses). With over 100 employees mostly exceptionally qualified industry scientists, and manufacturing professionals, Inventprise has created a large and dynamic presence in the Washington State Life Sciences environment.

Just - Evotec Biologics

Just - Evotec Biologics

Seattle, Washington, United States

Just – Evotec Biologics, wholly owned by Evotec SE, is a first-to-industry biologics platform that leverages AI/ML technologies and world-leading molecular design, cell line development, process intensification and continuous manufacturing strategies to advance biotherapeutics from discovery through clinical stages to commercial launch. The Just – Evotec Biologics team combines deep industry experience in the fields of data, protein, process, and manufacturing sciences including automation with highly integrated and flexible capabilities to break through the scientific and economic barriers associated with the development of protein therapeutics. Our focus is to accelerate and expand access to biotherapeutics through scientific and technological innovation for our proprietary projects and on behalf of our partners.

Kestra Medical Technologies

Kestra Medical Technologies

3933 Lake Washington Blvd NE, Suite 200, Kirkland, WA 98033, US

At Kestra, we stand for patients at-risk and the people who care for them. Together we work to protect, support, and empower them with wearable technologies, tools, and better answers as they navigate life's most challenging medical events. Cardiovascular disease is the number one cause of death globally. We're taking a fresh approach to cardiac monitoring and delivery of definitive therapy with wearable products and applications. We aim to make the entire recovery process easier for patients by bringing comfort and assurance to them—along with advanced clinical insights and tools to their medical care teams. Kestra is a privately held, Bain Capital portfolio company, headquartered in Kirkland, Washington USA. Visit us at www.kestramedical.com

Kinea Bio

Kinea Bio

3000 Western Avenue, Seattle, WA 98121

Kinea Bio is a patient-focused biotechnology company striving to accelerate the development of next-generation AAV-based gene therapies to treat various diseases. The company is located in Seattle, Washington and is dedicated to developing innovations to fight genetic diseases.

Kineta

Kineta

Seattle, WA

Kineta is a clinical stage biotechnology company with a mission to develop next-generation immunotherapies that transform patients’ lives.

Komo Biosciences

Komo Biosciences

Seattle, Washington, United States

Komo Biosciences is a revolutionary gene editing startup that has emerged with breakthrough integrase technology from the University of Hawaii. The company has launched from stealth upon publication of groundbreaking precision genome engineering discovery.

Küleon Bioscience

Küleon Bioscience

SEATTLE, Washington

Küleon is a drug discovery company leveraging proprietary, AI-based technology to identify novel serotonergic drugs for the targeted treatment of various neuropsychiatric diseases and disorders. We’ve created a proprietary portfolio of serotonin receptor ligands designed to target neurocircuit abnormalities in the brain that are responsible for difficult-to-treat disorders such as schizophrenia and depression. We have successfully identified several preclinical leads that have significantly improved agonism characteristics such as low-to-no hallucinogenic or cardiotoxic liability, as well as modified PK/PD profiles when compared to other known atypical antipsychotics and serotonergic drugs. Serotonergic drugs have the potential to address multiple indications affecting large population groups that make up extremely sizable markets. This is because many of the current SSRIs and non-selective serotonin receptor agonists were not designed with an eye towards functional selectivity. Our novel compounds are designed for functional selectivity via biased signalling mechanisms, potentially enhancing their therapeutic effect and reducing unwanted side effects. Our proprietary molecular scaffolds and compounds are novel and patentable, providing us with a tremendous strategic foothold in the market as companies continue to explore novel mechanisms of action for targeting neuropsychiatric diseases and disorders. We are collaborating with some of the world’s leading academic researchers and key opinion leaders in the serotonergic and atypical antipsychotic drug development space. Please reach out if you would like learn more about the work we are doing with our collaborators!

Link Immunotherapeutics

Link Immunotherapeutics

Seattle, Washington, United States

Link selects validated cancer targets and novel target combinations to build on existing knowledge in creating better molecules. Our strength as a leadership team comes from decades of previous experience and collaboration in both academic and industry environments. At Link, we know that our goal is elusive and that the work we do is not easy, but we are focused and determined to create better therapeutics. We are not alone. Our mission is supported by an outstanding Board of Directors and collaboration with industry-leading partners.

Lumen Bioscience

Lumen Bioscience

Seattle, Washington, United States

Lumen Bio is a clinical-stage biotechnology company developing topically and mucosally delivered biologic drugs to treat and prevent highly prevalent diseases.

MalarVX

MalarVX

Seattle, Washington, United States

MalarVx is a bio-pharmaceutical company located in theCenter for Infectious Disease Researchfacility in Seattle, Washington.MalarVxwas founded to address the myriad challenges of creating a safe, affordable, effective malaria vaccine using innovative new technologies discovered through research.They are focused on the development of in vitro culture systems for the malaria parasite which will lead to the development of an effective whole-parasite vaccine. Theycollaborate with researchers in non-profit institutions, university infectious disease programs, foundations committed to solving diseases of the third world, and for-profit pharmaceutical and medical devices companies.

Matchstick Technologies

Matchstick Technologies

Seattle, Washington, United States

Matchstick’s premier product, PIXUL (forPIXelatedULtrasound), is a tool that processes each and every well of a 96-well microplate consistently and quickly.

MicrobiomX

MicrobiomX

Seattle, Washington, United States

Fecal microbiota transplant (FMT) has been gaining traction among healthcare providers, researchers, and patients, with hundreds of clinical trials underway and compelling data on FMT benefits for a variety of medical conditions, far beyond its initial application for Clostridium difficile. However, existing FMT treatment methods are time consuming, costly, and sometimes invasive. The team at MicrobiomX recognized the opportunity to develop a scalable, safe, rapid FMT solution.

Mozart Therapeutics

Mozart Therapeutics

500 Fairview Ave N., Suite 600, Seattle, WA 98109, US

Mozart is developing disease-modifying therapies for autoimmune and inflammatory diseases that work by targeting a novel regulatory immune pathway.

Myosana Therapeutics

Myosana Therapeutics

Seattle, Washington, United States

Myosana Therapeutics, Inc. is leading the efforts in developing new gene therapies that will slow skeletal muscle degeneration and heart failure.

NapaJen Pharma

NapaJen Pharma

Seattle, Washington, United States

A pioneer in immuno-modulation by cell specific delivery of oligonucleotide drugs to antigen presenting cells completing IND enabling studies for a groundbreaking anti-GVHD drug for hematopoietic stem cell transplantation in hematological cancers.

Oisin Biotechnologies

Oisin Biotechnologies

Seattle, WASHINGTON (WA)

Oisin Biotechnologies is a longevity therapeutics platform company focused on creating genetic medicines to combat a variety of age related diseases. When cells detect that they have been irreversibly damaged, they enter a non-dividing condition known as cell-cycle arrest, or senescence. It’s believed this occurs to prevent cells from going rogue and turning cancerous. Ideally, they should die by the process known as apoptosis, but as we age, more and more frequently they don’t. They become zombie cells – unable to kill themselves or resume normal function. Senescent cells secrete molecules that cause inflammation in an effort to attract immune cells that would usually clear them. But for reasons that are not fully known, as we age, persistently senescent cells accumulate, leading to a vast number of age-related diseases. Oisín Biotechnologies is developing a highly precise, DNA-targeted intervention to clear these cells. As a recent study has shown, clearing senescent cells both reduces negative effects of aging pathologies and also extends median lifespan and survival.

Omeros Corporation

Omeros Corporation

Seattle, Washington, United States of America

Omeros is a Seattle-based biopharmaceutical company committed to discovering, developing, and commercializing small-molecule and protein therapeutics for large-market as well as orphan indications targeting inflammation, coagulopathies, and disorders of the central nervous system.

OncoResponse

OncoResponse

Seattle, Washington, United States

OncoResponse is an immuno-oncology biotech company that is leveraging its proprietary human antibody platform to discover novel targets and identify fully human monoclonal antibodies as therapeutics for the treatment of cancers. It identifies genuine human antibodies to a variety of high-value targets linked with immunosuppressive myeloid biology.OncoResponse's antibody pipeline is expected to alleviate TME immunosuppression and boost immune activation, turning cold tumors hot.

OncoSenX

OncoSenX

Seattle, Washington, United States

OncoSenX is a developer of transient gene therapies designed for solid tumors. The company is headquartered in Seattle, Washington and is focused on developing tumor-killing therapeutics using genetic information.

Oncotherapy Solutions

Oncotherapy Solutions

Seattle, Washington, United States

Oncotherapy Solutions LLC currently has three preclinical programs and a lead drug conjugate for ovarian cancer and triple-negative breast cancer. The lead drug conjugate is also expected to be effective on cancers of the colon, pancreas, lung and brain. The second research program is on the development of new multi-kinase inhibitors for the treatment of a variety of hematological and solid tumors. This program is in early proof of concept preclinical phase. The third research program is on the development of novel vaccines and checkpoint inhibitors to activate the patient's own immune cells to recognize and destroy cancer cells. This program is on hold until appropriate funds are secured.

Ora Biomedical

Ora Biomedical

Seattle, Washington, United States

Ora Biomedical, Inc. is a new pharmaceutical company in the longevity biotechnology sector that identifies and characterizes healthy aging therapeutics for further clinical and commercial development. Ora Biomedical separates itself from other longevity biotech companies by building in large-scale drug discovery and validation at the core of our scientific operations. With robust preclinical discovery at the heart of our approach, we identify novel aging targets and new interventions for known targets. Most importantly, we will leverage large-scale operations to perform drug studies that combine known and novel healthy aging interventions to identify those that produce breakthrough increases in healthy lifespan and/or mitigate disease-mediated pathology.

Organomics

Organomics

Seattle, WA 98208, US

The future of preclinical drug discovery is engineered tissue. The founders of OrganOmics have developed cutting-edge, live human brain tissue models derived from stem cells. They have partnered with the neurosurgeons to source patient-derived cancer tissue to induce a realistic cancer pathology. Their patented microfluidic platform automates the assay, detailing drug responses of thousands of tissues generating high-content data. This vast, cellular response data is processed through artificial intelligence to predict the clinical outcomes of each candidate drug.

Oricula Therapeutics

Oricula Therapeutics

Seattle, Washington, United States

Working to develop drugs that reducing or eliminatehearing loss due to aminoglycoside therapy.

Outpace Bio

Outpace Bio

Seattle, Washington, United States

Outpace is creating cell therapies with curative potential through protein design and cellular engineering. With an initial focus on solid tumors, Outpace is developing technologies that overcome the barriers to efficacy and safety by programming cells to make the right decisions inside patients. Outpace’s suite of technologies drive persistent activity of the cell therapy (OutLast™), recruit a productive immune response in the tumor microenvironment (OutSmart™), and achieve the potency (OutSpacers™), specificity (Co-LOCKR™), and safety (EGFRopt™) necessary to unlock diverse cancer indications. Outpace’s internal and partnered pipeline approach is optimized for rapid clinical validation of its technologies across diverse cell types and manufacturing processes. At Outpace Bio, we believe that the highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse, and inclusive culture for all employees.

PAI LIFE SCIENCES INC

PAI LIFE SCIENCES INC

Seattle, Washington

PAI Life Sciences is a biotechnology company located in Seattle, WA, specialized in the developmental and translational research necessary to bring products from the laboratory to bedside. Its mission is to address neglected diseases throughout the world with the idea of “serving the underserved.” The company has developed novel protein biotherapeutics and has a pipeline of products ranging from infectious disease vaccines and adjuvants to therapeutics for cancer.

PharmaIN

PharmaIN

Bothell, Washington, United States

PharmaIN Corporation is a company dedicated to developing proprietary peptide drugs for in-home treatment of liver disease and cancer. PHIN-214 is an investigational drug therapy that has not been approved by the FDA or any other regulatory agency.

Plurexa

Plurexa

Seattle, Washington, United States

Cell models for human disease.

Prevencio

Prevencio

Kirkland, Washington, United States

Prevencio is Revolutionizing Blood Tests For Cardiovascular Disease || Powered by Artificial Intelligence (AI) || Preventative Medicine for Heart Health Prevencio's purpose is to prevent the preventable. 80% of cardiovascular disease, including heart disease and stroke, are preventable (CDC). Prevencio's personalized blood tests provide earlier detection and prevention which can diminish unnecessary procedures and related side effects, as well as improve patient outcomes. Published in top-tier cardiology journals and presented at leading cardiovascular meetings, Prevencio's patented, proprietary technology has been used to create seven life-saving cardiovascular tests, with more in development.   Prevencio utilizes Machine Learning (Artificial Intelligence) + Multi-Proteomic Biomarkers + Proprietary Algorithms to deliver cardiovascular diagnostic & prognostic tests that are significantly more accurate than standard-of-care stress tests, individual biomarkers, genetic markers and clinical risk scores. To learn more visit us at: www.prevenciomed.com

Proniras Corporation

Proniras Corporation

Seattle, Washington

Proniras Corporation is a clinical-stage biotechnology developing novel small-molecule therapeutics for the treatment of substance use and specialty central nervous system disorders. The Company’s lead program PRN-001-01 (tezampanel) is being clinical developed as a treatment option for opioid withdrawal and related disorders of addiction. Although effective treatments exist for opioid addiction, painful and difficult withdrawal is one of the primary reasons why current treatment fails, and relapse occurs. By alleviating the symptoms associated with opioid withdrawal, Proniras hopes to help patients successfully discontinue opioid usage and sustain an opioid-free life. Proniras was formed in 2017 by Accelerator Life Science Partners.

Proviva Therapeutics

Proviva Therapeutics

901 Fifth Avenue, Suite 1200, Seattle, WA 98164

Viva BioInnovator (VBI) is the specialized investment and incubation division of Viva Biotech Holdings. We focus on the initial creation and development of biotech startups across all indications and drug types. During the early stages of drug discovery, we can nurture and accelerate a startup's growth from idea to clinical program. VBI's unique investment and incubation model started out of necessity in 2014. Our roots are in drug discovery services, where we operate world-leading and proprietary drug discovery platforms. While serving big pharma customers from around the globe, we came to realize the huge demand from many entrepreneurs who have great ideas but cannot receive funding to advance their plan due to lack of data. We saw the value in many of these innovative ideas and provided our CRO drug discovery services, operational support, and monetary backing to help these creative scientists embark on the "0 to 1"​ transformation. This spark launched our "equity for service (EFS)"​ investment and incubation model. VBI is based in Shanghai, with an office in Boston and personnel in California. As of early 2019, VBI has invested in over 30 companies out of the hundreds of proposals submitted for review and we plan to invest at a rapid pace in the years to come. The majority of our current portfolio companies are US based, but we are open to proposals globally and are excited to see new ideas that fit our investment strategy. If you would like to learn more about us, please visit: www.vivabioinnovator.com Or send an email to innovation@vivabiotech.com If you would like to learn more about our parent company, Viva Biotech, please visit: www.vivabiotech.com

Revalesio

Revalesio

Tacoma, Washington, United States

Revalesio is a clinical-stage pharmaceutical company committed to creating treatments for neurological diseases and conditions that lack adequate therapeutic options. Our therapies address cellular imbalances related to mitochondrial dysfunction and thereby modulate the immune response. They have been shown to protect neurons in models of chronic neurological diseases and improve recovery in acute neurological injury. We are partnering with internationally renowned scientists in biomedical research in a concerted effort to improve the lives of millions.

RJS Biologics

RJS Biologics

Seattle, Washington, United States

Cancer Drug Delivery Technology - enhances drug delivery with small molecule affinity-tethering compounds

Sage Bionetworks

Sage Bionetworks

Seattle, Washington, United States

Sage Bionetworks is a trusted nonprofit leader in data sharing and reuse, enabling a rapid acceleration in biomedical discoveries and the transformation of medicine. Our mission is to drive a new age of discovery through truly open science and radical collaboration. Better Science Together.

Sana Biotechnology

Sana Biotechnology

Seattle, Washington, United States

Sana Biotechnology is focused on utilizing engineered cells as medicines for patients. The ability to modify genes and use cells as medicines will be one of the most important advances in healthcare over the next several decades. Sana is building differentiated capabilities across the spectrum of cell and gene therapy. Three aspirations drive Sana as we look to discover treatments for patients with poor outcomes or currently untreatable diseases. The first is the ability to repair and control the genes in any cell in the body. We are advancing novel delivery technologies with the goal of being able to deliver any payload to any cell in a specific, predictable, and repeatable manner, paving the way for next-generation in vivo gene therapy. Next is the ability to differentiate pluripotent stem cells ex vivo into immune-cloaked functional cells with the aspiration of being able to replace any missing or damaged cells in the body. Last is a belief we can enable broader access to our therapies through focusing on scalable manufacturing solutions, the cost of manufacturing, and aligning with key stakeholders. Sana launched in early 2019 and has over 350 employees in Seattle, Cambridge, and South San Francisco. Sana was founded with the long view – bringing together great people and the best technologies to deliver on the challenging promise of using engineered cells to meaningfully change the outcome of many human diseases.

Seagen

Seagen

Bothell, Washington, United States

Seagen Inc., a biotechnology company, develops and commercializes therapies for the treatment of cancer in the United States and internationally. The company offers ADCETRIS, an antibody-drug conjugate (ADC) for the treatment of patients with Hodgkin lymphoma or CD30-positive T-cell lymphomas; PADCEV, an ADC targeting Nectin-4 for the treatment of advanced or metastatic urothelial cancer; and TUKYSA, an oral small molecule tyrosine kinase inhibitor for the treatment of adult patients with advanced unresectable or metastatic HER2-positive breast cancer. It also develops TIVDAK for metastatic cervical cancer and other solid tumors; Ladiratuzumab Vedotin, an ADC targeting LIV-1 for metastatic breast cancer and solid tumors; Disitamab Vedotin, a novel HER2-targeted ADC; and SEA-CD40, SEA-TGT, SEA-BCMA, and SEA-CD70 for various cancer diseases. Seagen Inc. has collaboration agreements with Takeda Pharmaceutical Company Limited; Agensys, Inc.; Genmab A/S; Merck; and RemeGen, Co. Ltd. The company was formerly known as Seattle Genetics, Inc. and changed its name to Seagen Inc. in October 2020. Seagen Inc. was incorporated in 1997 and is headquartered in Bothell, Washington. On Dec. 14, 2023, Pfizer completed the acquisition of Seagen.

Seal Rock Therapeutics

Seal Rock Therapeutics

Seattle, Washington, United States

Seal Rock Therapeutics, Inc. is discovering and developing small molecule inhibitors of ASK1 (apoptosis signal-regulating kinase 1), a protein that mediates apoptosis, inflammation, and fibrosis. Seal Rock is currently focusing its efforts on hepatic indications including NASH (non-alcoholic steatohepatitis), a condition resulting from fatty liver disease, characterized by hepatic inflammation and cellular damage that lead to liver fibrosis. Additional opportunities with ASK1 inhibitors include cardiac, immunological and neurodegenerative indications.

Seattle Cancer Care Alliance

Seattle Cancer Care Alliance

Seattle, Washington, United States

Seattle Cancer Care Alliance offers a bold and innovative approach in the prevention, treatment, and cure of cancer.Combining the talents, expertise, and resources of three world-renowned institutions—Fred Hutch, Seattle Children's, andUW Medicine—SCCAisable to offerpatients unprecedented survival rates.

Shape Therapeutics

Shape Therapeutics

Seattle, Washington, United States

Shape Therapeutics is a biotechnology company that combines breakthroughs in AI, RNA technology, and synthetic biology to create safe, effective, and accessible medicines to help as many patients as possible. The company was founded with the mission to make programmable RNA medicines available for everyone. Shape Therapeutics is pioneering the field of programmable RNA Medicines.

Singletto

Singletto

Seattle, Washington, United States

Active Protection™ from Pathogens. Confidence to Live Well. Singletto's novel Oxafence® technology is being developed to meet the needs of healthcare, military, industry, and consumers - providing ongoing Active Protection from pathogens where it matters most.

Sound Biologics

Sound Biologics

Bothell, Washington, United States

Sound Biologics creates innovative technology to better serve patients through the development of treatments for cancer. We aspire to discover and progress therapies that will impact human health and reduce the cost of biotherapeutics.

SoundHealth

SoundHealth

6400 Southcenter Boulevard, First Floor, Tukwila , Washington 98188, US

SoundHealth is on a mission to help the world breathe free. As a startup, we specialize in AI-based, personalized, drug-free treatment designed to improve respiratory health. SoundHealth is founded by an experienced team of serial entrepreneurs in the technology and medical fields. SoundHealth's inaugural product, SONU, is the world's first FDA-authorized wearable device offering drug-free, spray-free, personalized relief from nasal congestion.

Sound Pharmaceuticals

Sound Pharmaceuticals

Seattle, Washington, United States

Sound Pharmaceuticals, Inc. (SPI) is developing therapeutics that will enable doctors and patients to prevent and treat various forms of hearing loss. Sensorineural hearing loss is the third largest disease in the industrialized world and affects 50 million Americans. Estimates from the NIH and the CDC place the total annual costs of hearing loss at approximately $50 billion per year in the U.S. alone.

St Phi Therapeutics

St Phi Therapeutics

Hangzhou, Zhejiang Province, China

The mission of the company is to develop innovative diagnostic reagents, cellular therapeutics technologies and engineered cell products to help

Syntrix Pharmaceuticals

Syntrix Pharmaceuticals

Auburn, WA

Syntrix has pioneered the development of new therapies for over 10 years. As a clinical-stage company, we are tackling some of medicine’s most high-value diseases. One thing has remained unchanged however, our shared commitment to improving the lives of patients.

Systimmune

Systimmune

Redmond, Washington, United States

Located in Redmond WA, founded in 2014, Systimmune Inc. is a bio-pharmaceutical company focused on the treatment of cancer through developing novel therapeutic bi-specific, and tri-specific antibodies, as well as antibody-drug conjugates (ADC's). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the tumor and/or to activate the immune system to attack the tumor. We are a group of highly experienced immuno-oncology scientists utilizing several technology platforms to develop world class advanced antibody-based drug therapies.

Talus Bio

Talus Bio

Seattle, Washington, United States

Talus Bioscience is a venture-backed early-stage biotechnology startup company working on drug development for gene regulators. Talus Bio spun out of two leading institutions in September 2020 (University of Washington and Altius Institute for Biomedical Sciences) and is located in Seattle, WA. We are building a data-enabled drug development platform that will focus primarily on small-molecule drug development in oncology. Talus Bio's platform measures a drug’s ability to disrupt a gene regulator within its natural, non-engineered cellular environment. Furthermore, a single experiment using the platform measures activity for about 1,000 gene regulators simultaneously, providing information on in-cell drug activity and specificity in a single experiment. To accomplish this, we combine innovative cell processing with high-sensitivity quantitative proteomics and advanced downstream analytics. As a company, Talus Bio focuses on two parallel efforts to prove that our technology can open up the world of gene regulation for drug discovery: - Developing internal programs against previously undruggable gene regulators in cancers with poor standard of care - Partnering with pharma, biotech, and academic labs to help progress their pipeline of gene regulator drugs

Tasso, Inc.

Tasso, Inc.

1631 15th Ave W, Suite 105, Seattle, Washington 98119, US

Tasso is a fast-growing Seattle-based startup focused on delivering at-home diagnostic testing to those who need it most. We are growing our footprint with leading health systems, clinical research organizations, academic medical centers, and more who are looking to deliver clinical-grade, convenient diagnostic tests to their patients. Tasso was originally founded to find a better way to collect blood instead of a painful fingerstick or time-consuming venous draw. Since then, our products have been used in pharmaceutical clinical trials, by Olympians as part of a new virtual anti-doping program, and broadly by hospital systems across the US.

Tern Therapeutics

Tern Therapeutics

Washington, DC

TERN THERAPEUTICS is a privately-held biotechnology company founded in 2023 with a new vision for speeding the development of transformative, one-time gene therapy medicines for rare diseases. Guided by a team of leading physicians, scientists, and business leaders and in collaboration with patient communities, we are driven to deliver transformative treatments with urgency to those living around the world with rare disease.

TRIA Bioscience

TRIA Bioscience

1616 EASTLAKE AVE. E., SUITE 260, SEATTLE, Washington 98102, US

TRIA’s core competencies encompass the discovery and research of immune-based therapeutics. Developing vaccines for influenza, nicotine, and more.

Umoja Biopharma

Umoja Biopharma

Seattle, Washington, United States

Umoja is developing a new approach to cancer therapy that retools a patient’s immune system in vivo, enhancing the body’s natural capacity to fight cancer. We envision a world where all patients with cancer have access to the most advanced immunotherapies and are free from the burdens of traditional cancer therapies.

Uptake Medical

Uptake Medical

formerly Seattle and Orange County, Seattle, WA 98101, US

Uptake Medical® developed innovative medical technologies for the treatment of lung diseases. Its first product, InterVapor®, was the first and only approach to endoscopic lung volume reduction for people with severe emphysema that uses the body's natural healing process without leaving any foreign materials in the lung. Uptake Medical was acquired in July 2016 by Uptake Medical Technology Inc, a subsidiary of Broncus Holding Corp.

Variant Bio

Variant Bio

Seattle, Washington, United States

Variant Bio is developing therapies that will improve global health by studying the genes of people who are outliers for medically relevant traits. They’re using cutting-edge sequencing technology, statistical genetics, and machine learning to identify entirely new therapeutic targets.

Vilya

Vilya

Seattle & South San Francisco

Vilya is a computational biotechnology company creating a novel class of medicines to precisely target disease biology. The company’s proprietary platform, powered by advanced machine learning, taps into uncharted chemical space to design de novo molecular structures with enhanced drug-like properties that range in size between small molecules and antibodies. Vilya is leveraging its platform to focus on previously difficult-to-drug therapeutic targets. Vilya was co-founded by a team of scientists from the Institute of Protein Design (IPD) led by David Baker, Ph.D., and ARCH Venture Partners. The company has operations in Seattle and South San Francisco.

Visus Therapeutics

Visus Therapeutics

Seattle, Washington, United States

Visus Therapeutics - With offices in Seattle, Wash., and Irvine, Calif., Visus Therapeutics is a clinical-stage pharmaceutical company focused on developing innovative ophthalmic therapies to improve vision for people around the world. The company is developing novel miotic formulations for a once-daily eye drop to correct the loss of near vision associated with presbyopia. In parallel, Visus Therapeutics is focused on advancing its pipeline of early-stage ophthalmic product candidates with applications in ocular surface disease, glaucoma and age-related macular degeneration. Additionally, Visus Therapeutics has entered into a worldwide exclusive licensing agreement with DelSiTech Ltd, a leader in advanced, biodegradable, silica-based, controlled-release materials, to develop novel drug delivery technology that can help optimize the clinical benefit of ophthalmic therapies.

Wayfinder Biosciences

Wayfinder Biosciences

4000 Mason Rd, Seattle, Washington 98195, US

We are developing a platform for discovery of RNA-targeting small molecules to treat genetic diseases, neurodegeneration and cancer. We combine a proprietary high-throughput screening platform with machine learning models and unique datasets to accelerate development of drugs for previously undruggable targets. https://wayfinderbio.com

ZipBio

ZipBio

seattle, washington, united states

ZipBio is a biotech startup revolutionizing AI drug discovery with our cutting-edge protein design and drug discovery platform. We specialize in compressing biology to accelerate therapeutic innovation.