Revalesio is a clinical-stage pharmaceutical company focused on developing innovative treatments for neurodegenerative diseases, particularly through its lead drug candidate, RNS60. This proprietary technology utilizes nanotechnology to activate intracellular signaling pathways that have anti-inflammatory effects and promote mitochondrial biogenesis, cell survival, and differentiation. RNS60 is designed to protect neurons and oligodendrocytes in the central nervous system while modulating immune cell activity to restore cellular balance without the common side effects associated with many existing medications. The drug is currently being evaluated in clinical trials for conditions such as amyotrophic lateral sclerosis (ALS) and ischemic stroke, having received FDA Orphan Drug and Fast Track designations for ALS.

The company’s research highlights the significant role of mitochondrial dysfunction and neuro-inflammation in the progression of ALS, a condition affecting thousands in the U.S. RNS60 has shown promise in preclinical studies by providing bioenergetic support to motor neurons and reducing inflammation, which are critical factors in managing ALS. Additionally, Revalesio is exploring RNS60's potential benefits in treating ischemic stroke, a leading cause of mortality and disability. The ongoing clinical trials aim to establish the safety and efficacy of RNS60, with encouraging results reported in previous studies, indicating its potential to enhance recovery and improve the quality of life for patients suffering from these debilitating neurological conditions.

United States

Revalesio is a clinical-stage pharmaceutical company committed to creating treatments for neurological diseases and conditions that lack adequate therapeutic options.

Our therapies address cellular imbalances related to mitochondrial dysfunction and thereby modulate the immune response. They have been shown to protect neurons in models of chronic neurological diseases and improve recovery in acute neurological injury. We are partnering with internationally renowned scientists in biomedical research in a concerted effort to improve the lives of millions.

Revalesio

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