Matchstick Technologies specializes in advanced sample preparation solutions, particularly through their flagship product, PIXUL®. This innovative multi-sample sonicator is designed to streamline the processing of chromatin, DNA, RNA, and proteins from various sample types, including purified samples, cells, and tissues. PIXUL® allows for the simultaneous processing of 1 to 96 samples, significantly reducing bottlenecks commonly encountered in next-generation sequencing (NGS) applications. The device can accommodate up to 12 unique sonication conditions on a single 96-well plate, enabling rapid optimization for challenging samples. Its ultrasound-based technology generates microbubbles that collapse to create high shear stresses, effectively fragmenting samples into desired size ranges while maintaining cost efficiency through inexpensive consumables.

The PIXUL® system is designed for ease of use, providing consistent and reproducible results without the complexities often associated with traditional sample preparation methods. It eliminates the need for lengthy water degassing processes through a quick 15-minute coupling fluid circulation. The technology is particularly beneficial for chromatin immunoprecipitation (ChIP) workflows, where precise chromatin shearing is critical for successful analysis of DNA-binding proteins. By integrating PIXUL® into their protocols, researchers can achieve high-quality results in a fraction of the time, making it a valuable tool for laboratories focused on epigenetics and proteomics.

United States

Matchstick’s premier product, PIXUL (forPIXelatedULtrasound), is a tool that processes each and every well of a 96-well microplate consistently and quickly.

Matchstick Technologies

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