List of Surgical Devices Companies in Minnesota - 14

Aria CV, Inc: Improving the lives of patients suffering from the disease of pulmonary hypertension.

Francis Medical is developing minimally invasive treatment solutions for prostate, kidney, and bladder cancer through the use of convective thermal water vapor. Currently, the company is in clinical trials for ablating cancerous prostate tissue. Founded in 2018, Francis Medical is located in Maple Grove, Minnesota. Francis Medical, Inc., formerly named NxPhase Medical, Inc., is a company that was created after Boston Scientific (BSC) acquired NxThera, Inc. in April of 2018. As a part of the BSC/NxThera transaction, a separate and independent entity, NxPHASE Medical, Inc. (“NxPHASE”), was established, and shares of NxPHASE were distributed to the shareholders of BSC/NxThera. In addition, BSC/NxThera granted NxPHASE a license to utilize BSC/NxThera’s convective vapor ablation technology to develop, evaluate, and commercialize certain devices to treat prostate, kidney and bladder cancer (“NxPHASE Field of Use”), while BSC/NxThera remains focused on the treatment of benign prostatic hyperplasia. Late in 2018, NxPhase Medical, Inc. went through a rebranding process and selected Francis Medical, Inc. as its new brand and identity. The name and foundation of the company are a tribute to and legacy of Michael Hoey’s (founder/inventor) father, Francis Hoey, whose life was ended by prostate cancer with treatments that had harsh implications on his normal daily living.

Lifecore Biomedical is a full-service contract development and manufacturing organization (CDMO) that partners with pharmaceutical and biotech companies to develop and deliver vital and complex injectable therapies. We're also a manufacturer of premium sodium hyaluronate. From formulation to commercialization, we have everything it takes to move your project to the next level, making progress possible for our partners, people and most importantly, patients. Working from state-of-the-art facilities, our people are subject matter experts, our capabilities customized, our processes and systems qualified and our infrastructure optimized to meet your most sophisticated requirements regardless of scale. Our expertise is in drug products that are challenging and difficult to formulate, sterile filter, and aseptically fill. We've been the global leader in pharmaceutical-grade sodium hyaluronate (NaHy) for nearly 40 years. Leveraging this experience alongside deep expertise and capabilities in highly viscous solutions, we create tailored solutions that solve your drug development challenges across the entire development and manufacturing lifecycle. Our capabilities: Sterile Injectable Development - Formulation Development - Sterilization Development - Process Development - Analytical Services & Stability - Engineering Services - Validation Services Sterile Injectable Manufacturing - Sterilization - Aseptic Filling - Packaging - Analytical Services & Stability

Medtronic plc is an Irish medical device company. The company's operational and executive headquarters are in Minneapolis, Minnesota, and its legal headquarters are in Dublin, Ireland. Medtronic operates in more than 140 countries and employs over 90,000 people worldwide. The company is the world's largest standalone medical technology development company.

Headquartered in Minneapolis, Minnesota, Metavention, Inc. is a privately held medical device company developing novel treatments for metabolic diseases

Since 1996, Minnetronix Medical has accelerated medical device breakthroughs as a design, development and manufacturing partner to leading device companies around the world. Today, through life-cycle efficiency, opportunity realization, and increased utility, the organization is creating value in key technology segments, including RF energy, fluid and gas management, optical systems, and stimulation and active wearables. From design and manufacturing services to whole product solutions, Minnetronix brings expansive industry insight and intentional technical acumen, delivering better medical devices to market, faster. Minnetronix is based in St. Paul, Minnesota. ​

Monteris is a private equity backed neurosurgical company focused solely on diseases of the brain. The company was founded in Winnipeg, Canada in 1999 to create neurosurgical technology that, when used by neurosurgeons, would allow them to ablate brain tumors and lesions that may be difficult to approach via traditional methods. The NeuroBlate® System is a minimally invasive robotically controlled laser thermal therapy that uses MRI-guided laser light to ablate (destroy) unwanted tissue in the brain where a lesion, or abnormal tissue, originates. Monteris has offices in Minnetonka, Minnesota, USA and Winnipeg, Manitoba, Canada.

NeoChord is a privately held medical technology company leading the advancement of beating heart mitral valve repair in patients suffering from mitral valve regurgitation. The company's flagship product, the NeoChord Artificial Chordae Delivery System, received CE market clearance in December 2012.

ABOUT SONEX HEALTH "Refined simplicity" is the guiding principle behind Sonex Health, Inc., to drive efforts and innovations that result in elegant, effective solutions to some of the healthcare system's most pressing needs. Mayo Clinic physicians Darryl Barnes, MD and Jay Smith, MD and business operations expert Aaron Keenan founded Sonex Health in 2014. Sonex Health has developed UltraGuideCTR™ with Meerkat Technology™ to treat carpal tunnel syndrome through a less invasive approach while using real-time ultrasound guidance. Carpal Tunnel Release with UltraGuideCTR and real-time ultrasound guidance allows a procedure that once took place in an operating room to be safely and effectively performed in a surgery center or office setting, resulting in rapid patient recovery, improved cosmesis, and reduced costs. ABOUT UltraGuideCTR The low profile UltraGuideCTR™ with Meerkat Technology™ enables physicians to perform Carpal Tunnel Release surgery through a small wrist incision under real-time ultrasound guidance. CTR with ultrasound guidance relieves the symptoms of carpal tunnel syndrome while minimizing recovery time. Most patients can return to work and the activities in 3-6 days while enjoying immediate motion so they can focus on getting back to their lives and the activities they love. ABOUT UltraGuideTFR Performing trigger finger release with UltraGuideTFR and real-time ultrasound guidance allows for concurrent visualization of the internal structures of the palm and fingers. The ability to identify key anatomical landmarks via ultrasound supports a safe and successful transection of the pulley through a single small incision.

Spineology's OptiMesh is the only conforming, patient specific lumbar expandable implant on the market. OptiMesh is delivered through the smallest insertion profile, dynamically conforms to a patient’s unique endplate morphology, and powerfully expands to one of the largest implant footprints available. Spineology’s OptiMesh features our unique Conform and Expand™ technology, enabling a custom anatomical fit for lumbar fusion surgical patients. OptiMesh is designed to overcome the challenges of static and mechanically expandable implants.

Surmodics is the global leader in surface modification technologies for intravascular medical devices and a leading provider of chemical components for in vitro diagnostic (IVD) immunoassay tests and microarrays. Surmodics is pursuing highly differentiated medical devices that are designed to address unmet clinical needs and engineered to the most demanding requirements.

CAUTION -– Investigational device. Limited by Federal (or United States) law to investigational use. SynerFuse is long-term pain management without the use of addictive opioids. SynerFuse combines two FDA-approved technologies and synergistically fuses both in order to attack the problem of long-term, post-surgery, lower back pain, with a preemptive, drug-free pain management system.

Founded in 2015, Visura is a medical device company dedicated to delivering state-of-art visualization solutions to improve the quality of transesophageal echocardiogram probe intubations. Visura has developed the TEECAD System, the world's first, FDA-cleared, disposable camera that seamlessly connects to a TEE probe, providing physicians real-time visualization for more efficient and effective probe placement.

GOAL: DISPRUPT AND TAKE OVER AN OLD AND OVERLOOKED $150 MILLION/YR. MARKET BY LEVERAGING OUR SUPERIOR AND CLINICALLY PROVEN DEVICE DESIGN WHY IS IT POSSIBLE? Current oral airways have been continually proven to be defective and studies have proven that these common airways are not adequate to maintain the oropharynx airway. Further, they are not designed to control the ever-problematic tongue. Even more, our studies showed that current oral airways possess no proportional dimensional standards in relation to how it would impact the oropharyngeal area. THE PROBLEM The biggest impediment, after placement of an oral airway, is the relaxation of the soft tissue structures in the hypopharynx. These structures are inclined to collapse, thus obstructing airflow, while occurring from both front-to-back and side-to-side, thus greatly decreasing the size of the oral opening. In relation, literally every patient before and after anesthesia, CPR, or sedation, is provided with a manual jaw-thrust to prevent the tongue from falling back and obstructing the airway. Furthermore, almost every patient intubated is provided with an airway to prevent biting of the soft endotracheal tube. Both of these procedures involve manually protracting the lower jaw by pulling it forward relative to the upper jaw. SOLUTION Studies have proven that mandibular advancement increases the oropharynx opening under anesthesia, but nobody designed that embodiment into an oral airway, or thought to design an airway to also control the tongue…until now. INTRODUCING OUR LOWER-JAW THRUST (LJT) ORAL AIRWAYS WHICH ARE ENGINEERED TO INCREASE THE OPENING OF THE OROPHARYNX AIRWAY & CONTROL THE TONGUE