List of Biologics Companies in Wisconsin - 19

Proprietary products for the prevention and treatment of multi-drug resistant Gram negative bacterial infections.

BrainXell focuses on neural cells for therapeutic development. Founded in 2015 by Prof. Su-Chun Zhang with help from the Discovery to Product (D2P) program of University of Wisconsin Madison, it is based on the proprietary technology of directed differentiation of human stem cells (including induced pluripotent stem cells) to highly enriched subclasses of neurons. BrainXell is developing drug discovery / toxicology testing platforms using patient-derived or genetically modified stem cells and provides large-scale production of highly enriched, functionally specialized neural cells to the pharmaceutical and biotechnology industry.

Cultured Decadence is a Wisconsin-based cellular agriculture company using cell culture and tissue engineeringtechnologies to make lobster meat directly from the animal's cells.

Our company specializes in the development and performance of tissue-based testing, focused on histopathology and protein expression, to improve the understanding and pace of treatment development for genetic diseases.

Endsulin is a pre-clinical stage gene therapy company whose mission is to end insulin dependence for good and free people from being defined by diabetes. Our approach employs a widely studied and proven viral vector to deliver our patented genetic factor to the liver and restore the body’s own ability to produce and regulate insulin. With a single administration, Endsulin’s revolutionary genetic therapy for T1DM delivers a patented genetic factor that will “switch on” new insulin-producing cells to confer years – and perhaps a lifetime – of freedom from injecting artificial insulin, realizing the goal that has eluded researchers since the discovery of insulin. Founded by an award-winning transplant surgeon and world leader in diabetes care and supported by a team of experts in gene therapy, endocrinology, diabetes science, and pharmaceutical development, Endsulin has the scientific, medical, and commercial expertise to develop its innovative therapy quickly, filling an enormous unmet need and bringing us one step closer to ending insulin dependence for good — and for the good of everyone with T1DM.

FluGen, Inc. is a clinical-stage vaccine company transforming vaccine efficacy in respiratory diseases.

Fujifilm Cellular Dynamics, Inc. develops and manufactures biologically relevant human cells derived from induced pluripotent stem (iPS) cells. Our iCell® and donor-specific MyCell® Products are highly pure, highly reproducible, and available in industrial quantity to enable drug discovery, toxicity testing, stem cell banking, and cell therapy development.

Invenra offers flexible partnering options to meet diverse antibody discovery needs, from rapid, focused bispecific antibody discovery to comprehensive, collaborative development partnerships. Our new rapid bispecific discovery service, powered by the B-Body® Bispecific Platform, identifies bispecific lead panels within four months through functional screening of over 250 bispecific combinations, using mAbs derived from 90 parallel discovery screens. For those seeking a strategic, partnered approach, Invenra provides tailored support across all stages of discovery, from custom antigen design and assay development to in-depth biological analysis. This dual offering allows us to address a broad spectrum of objectives, from expedited project timelines for focused discovery services to fully integrated solutions for collaborative development partnerships.

JangoBio is developing regenerative therapies to reverse hormone imbalances associated with aging and thereby mitigate the risk of developing a wide range of age-related diseases. Pharmaceutical treatments, such as hormone supplementation, do not address the underlying loss of function, and can have significant side effects.

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Morgridge Institute for Research is a scientific research institution that focuses on biomedical research and innovation.

NeoClone produces high-quality monoclonal antibody products for the biotechnology and research markets. In addition to generating monoclonals through the traditional fusion technology NeoClone holds exclusive license to the ABL-MYC retroviral transformation system, a technique that produces monoclonal antibodies -- "NeoClone®"-brand or "NeoAb®" antibodies -- in an accelerated time and with cost savings. This allows NeoClone to provide custom antibodies faster and more cost effective.

Nimble Therapeutics is a biotechnology company dedicated to delivering on the promise of oral peptide therapeutics. Leveraging a paradigm-shifting peptide drug discovery and development engine, Nimble is advancing its internal pipeline and continues to support several partnered programs. The Nimble platform combines massively parallel solid-phase synthesis, unrivaled chemical and structural diversity, sophisticated assays, and powerful machine learning and computational methods.

Opsis Therapeutics is a company focused on advancing the pipeline of cell replacement therapies targeting ocular diseases. Leveraging innovations in induced pluripotent cell (iPSC) generation, retinal cell differentiation, and functional biomaterials, Opsis Therapeutics is developing cell therapies for patients with dry age-related macular degeneration (AMD), inherited macular degenerations (IMDs) and inherited retinal diseases (IRDs). Founded in 2016, Opsis Therapeutics is a joint venture of FUJIFILM Cellular Dynamics and David Gamm, M.D., Ph.D., and is headquartered in Madison, Wisconsin.

Vascugen is dedicated to revolutionizing the standard of care for millions of patients suffering from severe conditions caused by restricted blood flow, particularly for those patients at high risk for amputation and death for whom few to no treatment options remain. The company’s lead product is an allogeneic vasculogenic cell – a cell with the potential to forge new blood vessels in oxygen-starved tissues. The vasculogenic cell product is manufactured from induced pluripotent stem cells (iPSCs), which provide a limitless source from which to produce off-the-shelf, cryopreserved doses at scale.

As a recognized world leader in pluripotent stem cell banking and characterization, WiCell provides the stem cell community with high-quality cell lines as well as accurate and reliable cell characterization and cytogenetic testing services. We offer both cGMP and research grade services and cell lines to fit your lab's needs. In addition, WiCell offers affordable and reliable long-term LN2 storage through our WiCellSAFE program to safeguard and protect your research investment.

We partner with companies to create innovative solutions, driving the advancement of revolutionary medicine. Our primary goal is for patients to receive therapies more efficiently, while keeping safety and quality at the absolute forefront. We specialize in producing cutting-edge equipment for downstream processing, particularly in the critical stages of fill and finish. Additionally, we have expertise in designing tailor-made equipment for cell and gene therapy.