List of Vaccines Companies in India - 10

Bharat Biotech International Limited is a multidimensional biotechnology company specializing in product-oriented research and development leading to the manufacture of vaccines and bio-therapeutics in Hyderabad, India. Bharat Biotech was established in the year 1996 by Dr. Krishna M. Ella and Mrs. Suchitra K. Ella. Bharat Biotech is a pioneering biotechnology company known for its world-class R&D and manufacturing capabilities. Our mission is to deliver affordable, safe and high-quality vaccines and bio-therapeutics that help people prevail over diseases. We seek to lead innovation in biotechnology in order to lead the fight against disease with a focus on emerging markets. Our significant R&D investments have yielded several breakthroughs including the world’s 1st Eco-friendly recombinant Hepatitis-B vaccine (free of cesium chloride and Thiomersal).Rotavirus vaccine from a naturally attenuated strain,Typhoid Conjugate vaccine. Transparency and openness are central to our DNA. An uncompromising commitment to integrity differentiates us. Our clinical trials are known for their rigor and breadth. We also adopt the most comprehensive data integrity procedures to ensure that we capture, store and report data accurately. We are committed to provide affordable and innovative vaccines for healthier lives. Bharat Biotech launched India’s first recombinant Epidermal Growth Factor (REGEN-D®) to combat diabetic foot ulcers, burns. Typbar TCV® is the world’s first clinically proven conjugate Typhoid vaccine and received WHO-Prequalification in January 2018. ROTAVAC® was India’s first and largest efficacy clinical trial on vaccines and Rotavac® received WHO-Prequalification in January 2018. Bharat Biotech Launches ROTAVAC 5D®- Lowest dose volume Rotavirus vaccine - ROTAVAC in the world launched in December 2019. COVAXIN, India's indigenous COVID-19 vaccine by Bharat Biotech.

Bharat Serums And Vaccines Limited (BSV) is one of the fastest growing biopharmaceutical companies in India. For 50 years now, BSV has used its scientific resources to develop a range of biological, biotech and pharmaceutical products. Today, as we influence patient outcomes in the therapeutic areas of Women’s health and Critical Care and IUI-IVF, we have the privilege of being a partner of choice. BSV's product portfolio includes plasma derivatives, monoclonals, fertility hormones, antifungals, anaesthetics, cardiovascular drugs, and equine immunoglobulin /antitoxins. In addition, BSV offers products in the areas of gynaecology, assisted reproductive technology, critical care, emergency medicine, neurology, nephrology, haematology, and urology. The company provides its products to retail outlets and hospitals through distributors primarily in India, as well as in the Asia Pacific, the Russian Federation, CIS countries, Latin America, Africa. BSV is amongst the top 10 Biotech companies in India. The Company has in its portfolio over 145 brands. The company has over 1000 employees selling its products across the country. Our brands are marketed all over India and exported to over 70 countries across the world We have an open and entrepreneurial culture, with each of our employees taking on significant responsibility in each activity of our value chain, be it in terms of research & development, manufacturing, quality, sales & marketing, distribution, business development or organisation building. Advent International, a global private equity firm has endorsed its faith in our commitment towards bringing life to life

Biocon: Enhancing Global Healthcare Biocon Limited, publicly listed in 2004, is India's largest and fully-integrated, innovation-led biopharmaceutical company. It is an emerging global biopharmaceutical enterprise serving customers in over 120 countries. Driven by a vision to enhance global healthcare through innovative and affordable biopharmaceuticals, we have enabled access to advanced therapies for diseases that are chronic, where medical needs are largely unmet and treatment costs are high. The early anticipation of the increasing dominance of biologics in global development pipelines helped us to be ahead of the curve in crafting a differentiated product portfolio based on fermentation and recombinant technologies, which straddles fermentation-derived small molecules and biologics, both novel as well as biosimilars. The significant brand equity that we have built worldwide for our small molecule APIs across statins, immunosuppresants and other specialty products has made us a leading global supplier of these products. We have also built one of the largest and most diverse biosimilar pipelines, spanning insulins, monoclonal antibodies and other recombinant proteins that address critical chronic diseases such as diabetes, cancer and autoimmune disorders. Ranked among the Top 3 biosimilar players globally for rh-insulin and insulin glargine in volume terms, we are the first Indian company to launch a biosimilar in Japan with Insulin Glargine, which also has been approved for sale in EU and Australia. Our insulin products have made a difference to the lives of millions of people with diabetes across the globe. We now aim to provide our insulin products to ‘one in five’ people with diabetes in need of insulin-based therapy anywhere in the world within the next 10 years. We are also making a huge impact in the area of cancer care. Our biosimilar Trastuzumab, which was the first to be approved anywhere in the world and launched in India in 2014, has helped treat several thousand HER2-positive metastatic breast cancer patients. We are also the first company from India to get its biosimilar approved by the USFDA; Ogivri™, co-developed by Biocon and Mylan, is the first biosimilar Trastuzumab to be approved in the US. In addition to Trastuzumab, several of our biosimilar assets are on track for anticipated regulatory approvals in developed markets. We are also developing a pipeline of patented biologics to address global unmet medical needs. We have successfully launched a couple of novel biologics in India: Nimotuzumab for the treatment of head and neck cancer and Itolizumab to tackle psoriasis. Besides these, we have a basket of novel assets are under various stages of clinical development, including a high potential oral insulin. Through our subsidiary, Syngene, we offer a suite of integrated, end-to-end discovery and development services for novel molecular entities (NMEs) to the global life sciences sector. Ranked by the prestigious Science magazine among the Top 10 Best employers in the biotech industry, Biocon is passionately pursuing a mission to rationalize healthcare spends, enhance access to life-saving therapies and make a significant impact to global healthcare through ‘blockbuster’ drugs with the potential to benefit a billion patients.

Epygen Biotech private limited is a Biotechnology organization promoted by the founders of Epygen Labs, bringing along decades of precious experience in Biotech research and successful business. With offices, labs and manufacturing facilities in Dubai, India and USA, Epygen Biotech exhibits unique capabilities in the Biotechnology field, where it has developed a strong pipeline of therapeutic proteins for Cardiovascular, Oncology and Immune disorders. With focus on Biosimilars and Novel Biologic Entities, Epygen utilizes its skills in molecular biology, fermentation and protein engineering to produce Biologics in an affordable way, meeting global regulatory standards.

Gennova Biopharmaceuticals Ltd. is a biotechnology company based in Pune, Maharashtra, India. The company specializes in the research, development, production, and commercialization of biotherapeutics and vaccines aimed at treating life-threatening diseases in areas such as cardiovascular, neurology, nephrology, and oncology. Gennova employs advanced recombinant DNA technologies and innovative bio-manufacturing practices to create effective biotherapeutic solutions. The company utilizes various expression platforms, including bacterial, mammalian, and yeast-based systems, to produce its recombinant products. Gennova has successfully commercialized seven products, including Tenectase, a biosimilar for treating Acute Ischemic Stroke, and HAMSYL, a treatment for acute lymphoblastic lymphoma offered at a lower price point for better accessibility. With a strong focus on research and development, Gennova is recognized as a preferred partner in the vaccine sector for research and cGMP manufacturing. The company employs around 598 people and has reported a revenue of $2.8 million, positioning itself as a notable player in the Indian biotechnology landscape.

Indian Immunologicals Ltd (IIL) is the market leader in veterinary and human biologicals in India. It manufactures over 150+ products. IIL operates one of the largest plants in the world for veterinary vaccines. IIL has adequate infrastructure and cold chain distribution capability to reach out to various parts of India and world market. This flexibility in logistics has ensured many products of IIL occupy top slots in the market. IIL is a major player in the human vaccine market in India, focusing on the pediatric and rabies vaccine segments. IIL is also a major supplier of pediatric vaccines to India’s large Universal Immunization Programme. Brief History of IIL: Indian Immunologicals was established by the National Dairy Development Board (NDDB) in 1982, as its unit, with the objective of making vaccines available to farmers at an affordable price. The unit was incorporated as Indian Immunologicals Limited in the year 1999. IIL started manufacturing human vaccines in 1998 on a specific request by the Government of India. IIL is the second company in the world and first in India to launch purified vero cell rabies vaccine (PVRV) and markets it under the brand – Abhayrab. This led to the discontinuation of use of older and unsafe sheep brain derived vaccine (also termed Nerve Tissue Vaccine – NTV) in the country. IIL has also been exporting Animal Health vaccines,formulations & Human Health vaccines, to more than 50 countries. IIL not only provides products and services to enhance the quality of livestock in the country, but also utilizes its technological capabilities for the benefit of the people.

Mynvax is a developer of novel recombinant vaccines to fight the human influenza virus and COVID19. The company is focused on developing next-generation vaccines for influenza and other respiratory viruses. Mynvax has raised a total funding of $7.22M over 3 rounds from various investors. It is a clinical stage vaccine biotechnology company with a vision to create efficacious vaccines for respiratory viruses.

Panacea Biotec is a research-based health management company involved in research, manufacturing and marketing of high-quality, affordable pharmaceutical, vaccines and herbal products. The product portfolio includes highly innovative prescription products in important therapeutic areas like pain management, diabetes, cardiovascular, renal disease management, osteoporosis, gastro-intestinal care products and vaccines. Panacea Biotec is committed towards disease prevention by introducing Innovative Vaccines that helps to reduce child mortality. Our portfolio consists of worlds first fully liquid Hexavalent vaccine i.e. EasySix (DTwP-Hib-HepB-IPV), the world’s first fully-liquid Pentavalent vaccine i.e. Easyfive-TT (DTwP-Hib-HepB), Oral Polio vaccines (like bOPV, tOPV, mOPV), etc. We have a high-impact pipeline of vaccines including Pneumococcal conjugate vaccines (PCV), tetravalent dengue vaccine, etc. We have supplied 10+ billion immunizations of Polio vaccines in last 20 years, 150+ million immunizations of Novel Innovative fully liquid wP-based vaccines like the wP-Hexavalent vaccine (DTwP-Hib-HepB-IPV). And are a trusted partner for WHO, GAVI and UN Agencies with track-record of sustainable supplies for UNICEF, PAHO, and National Immunization Programs. In Pharmaceuticals, we have discovered and commercialised a NCE, Sitcom – that helps in Haemorrhoids and Piles. It is the leading brand in its segment in India and many other countries. We also have built leading brands like Pangraf, Mycept, Glizid, Livoluk, and PacliAll across transplantation, diabetes, constipation, and oncology. Our facilities are WHO Prequalified, US FDA approved and cGMP compliant. Our products are available across more than 145 countries including US, Germany, among other markets.

PopVax is an Indian biotechnology company based in Hyderabad building a novel thermostable, low-cost, and safe second-generation mRNA platform for rationally-designed broadly-protective multi-epitope vaccines. We're starting with an open-source 4-8 °C refrigerator-stable booster candidate that is intended to protect against the entire sarbecovirus sub-family, including current and future strains of SARS-CoV-2 (the virus which causes COVID-19), and some other beta-coronaviruses such as MERS-CoV. PopVax's work has been funded primarily via collaboration with the Bill & Melinda Gates Foundation (India) and Vitalik Buterin's Balvi. Our India-based team of 30 researchers and senior manufacturing leaders includes experts in antigen design, mRNA sequence optimization and synthesis, and nucleic acid delivery from top Indian and North American research institutions, including CCMB, CDFD, IIT Delhi, IAVI, Harvard, Scripps, and UBC, as well as vaccine & biologics production veterans from companies including Sanofi, Biocon, Panacea Biotec and Biological E. The smaller scientific team for our US-based subsidiary, PopVax North America, is led by Moderna's first Director of Chemistry, and includes several leading practitioners of de novo computationally-driven rational protein design for novel vaccine immunogens.

Premas is developing transformational technologies and partnering with pharmaceutical companies around the world to expedite their drug discovery programs by cutting down significantly both on costs & time to clinics. Axtex-4D, a three-dimensional cell culture platform, engineered to produce high-throughput screens for targeted immuno-oncology drug candidates, is compelling scientists to relook at their tumor-targeting strategies. The ex-vivo culture systematically mirrors the in-vivo tumor microenvironment and is poised to revolutionize both drug discovery & combinatorial therapies. D-Crypt, a platform for 'difficult-to-express' proteins, is designed to considerably reduce time, cost, and risks associated with producing high-quality recombinant proteins. D-Crypt combines a yeast expression host with over 20 custom-made expression vectors. C-Qwence, our naive India-based Antibody Library is harnessing the power of a genetic pool that is more diverse than any other region and has exposures to infectious diseases and changes in an environment not seen in Europe or America. C-Qwence captures a wealth of novel genetics and protective immune responses, demonstrated in the unique profiles of individual antibodies isolated from the libraries. Combining our breakthrough technologies with state-of-the-art Gene to IND biologics development capabilities, Premas is seeking new partnerships with pharmaceutical companies to help accelerate the delivery of new medicines to patients.