List of Surgical Devices Companies in Pennsylvania - 8

Actuated Medical has quickly emerged as a leader in the design and development of medical devices and components. Using proprietary actuation technologies, our innovations address a wide variety of medical challenges ranging from clearing occlusions to easing tissue penetration to enabling MRI assisted procedures. From start to finish, our team designs, develops and manufactures under an ISO-certified quality control system. In addition, we continually seek feedback from domain experts to ensure our products not only solve real problems but also are readily accepted by clinicians. With a proven track record of receiving federal grants to support research and development, the company has built a successful business model that takes medical devices from conception to regulatory approval to market.

At Best nomos we design products and solutions that help medical professionals treat a variety of cancers. We are best known for our innovations in IMRT and IGRT. As one of the newest members of the Best family of companies, our aim is to expand our product selection beyond imaging technology to become the Single Source Oncology Solutions provider of choice for our customers.

Escalon, operates in the healthcare market, develop, manufacture, marketing, and distribution of medical devices for use in ophthalmology.

H.B. Fuller | Adhezion Biomedical, LLC is a medical device company focused on the development and commercialization of highly differentiated cyanoacrylate based surgical, wound management and infection prevention technologies. Founded in 2001, the company is based in Wyomissing, Pennsylvania. The vision of the Adhezion team is to redefine the way cyanoacrylate based surgical adhesives and sealants are used in medicine. Our mission is to provide technologies that achieve optimal patient outcomes. Adhezion currently is developing and commercializing cyanoacrylate‐based adhesives and sealants for use in both professional and consumer healthcare settings.

Neuraptive Therapeutics is a medical technology company that specializes in bringing novel therapeutic technology for the acute surgical repair of injured peripheral nerves.

Orchestra BioMed biomedical innovation company focused on developing transformative therapeutic products for large unmet clinical needs in procedure-based medicine.

INNOVATIVE BONE GRAFTS BASED ON IMPROVED BIOACTIVE GLASS Synergy has identified an optimal bioactive glass particle with a spherical shape and a biomodal size range that has been shown to significantly improve bone healing. Synergy's BioSphere® particles have been engineered to maximize the bone healing potential of bioactive glass. Synergy Biomedical is a privately-held medical device company focused on bringing biomaterial based products to the orthopedic and spinal surgery markets. Synergy's BIOSPHERE Technology represents an innovative approach to advancing bone graft technology, and improving bone healing and patient outcomes. Synergy Biomedical welcomes inquiries from independent sales distributors with an understanding of orthopaedic and spinal surgery. We are looking for distributors with a proven track record who are willing to grow our bone graft market. Please visit our website for more information: www.synergybiomedical.com

Thrombolex is engaged in the design, development, and distribution of innovative endovascular catheters used in interventional procedures, particularly in pharmaco-mechanical catheter-directed thrombolysis (PM-CDT) in patients who suffer from arterial and venous thromboembolic (A&VTE) conditions. The Company is currently marketing seven (7) different FDA-cleared devices that are all based on the BASHIR™ Endovascular Catheter platform technology.