List of Software Companies in Massachusetts - 40

4G Clinical’s suite of innovative RTSM and clinical supply optimization software provides the right-sized support for any phase or trial complexity. At 4G Clinical, all studies are supported by a team of RTSM experts to advise trial teams on the best path forward. Our operations team distinguishes itself through their extensive industry expertise and deep understanding of trial designs and mid-study adjustments. 4G Clinical is committed to helping sponsors and CROs follow the science, wherever it may lead, as quickly and as safely as we can. While we will not discover the next novel compound in the lab, we are doing our part by leveraging our extensive experience and technological innovations to bring speed and agility to clinical trials. As a critical partner throughout clinical development, we can help you seamlessly transition and scale your trials through both protocol and supply complexities to help bring crucial medicines to those who need them, faster. To learn more about how we are tackling the bottlenecks in clinical trials through our innovative solutions, Prancer RTSM® and 4C Supply®, visit us at www.4gclinical.com.

At Activ Surgical, our mission is for every surgical imaging system to deliver intelligent information that reduces surgical complication rates, ushering in a new standard of patient care and safety. Having completed the world’s first autonomous robotic surgery of soft tissue in 2018, the company is focused on enhanced, real-time visualization capabilities for surgeons that combine advanced augmented reality (AR), artificial intelligence (AI), and machine learning (ML) technology. Our vision is to transform the collective surgical experience by leveraging emerging technologies and data into insights that make world-class surgery accessible for all.

Admetsys is a biomedical technology company specializing in critical care automation. The company's flagship PrecisionOne system is the first fully automated glycemic control system and continuous blood diagnostics platform for hospital care. The company was founded to commercialize the next generation of medical automation technology: continuous real-time biosensing, robotics, artificial intelligence and learning algorithms, intelligent therapeutic delivery, and advanced data telemetry.

Boston-based AI Proteins is a biotech company on a mission to re-imagine protein therapeutics with a novel approach for designing entirely new proteins. Using AI-based design and a high-throughput drug discovery platform, AI Proteins creates de novo proteins optimized for specific therapeutic applications. The AI Proteins platform enables the development of inexpensive, durable, highly specific proteins that have the potential for oral delivery. Additionally, the AI Proteins platform can dramatically accelerate the development of lead therapeutic candidates ready for IND enabling studies.

Arxspan provides cloud-based solutions to meet the scientific data management needs of leading life sciences, chemicals, and scientific companies globally. Arxspan offers ArxLab®, a suite of web-based scientific informatics applications, allowing scientists to record, manage, and share their research data​: * Notebook - Intuitive electronic laboratory notebook (ELN) optimized for collaborative models in current research environments * BioReg/ChemReg Registration - Configurable repository for registering unique chemical/biological entities and subsequent batches * Assay - Flexible system for registering assay protocol and result data * Inventory - Comprehensive tool for defining and managing chemical and biological compounds, reagents, equipment, and other items * Search - Robust decision support platform for querying, visualizing, and reporting data * Workflow - ArxLab Workflow allows users to create new work requests and to assign them to users and/or groups. The workflow management tool enables scientists to manage and prioritize all scientific projects, as well as to make procedure requests to internal colleagues and external partners. For more information, please visit our website at www.arxspan.com

Asimov's mission is to advance humanity's ability to design living systems, enabling biotechnologies with outsized societal benefit. The company is developing a synthetic biology platform from cells to software to design and manufacture next-generation therapeutics, including cell & gene therapies, through a combination of products, services, & collaborations. Founded by bioengineers from MIT and Boston University and headquartered in Boston, the company has raised over $200 million.

BostonGene is pioneering the use of biomedical software for advanced patient analysis and personalized therapy decision making in the fight against cancer.

Catalog is developingtechnology to store digital information in DNA molecules.

Centaur Labs is the modern data labeling solution for AI innovators across the healthcare landscape. With an expert crowd of 50k+ labelers and a gamified app to incentivize and quality-control them, our scaleable labeling methodology ensures high-quality labels in as little as 24 hours.

Cytel is the world's leading data-science CRO, driving advancements in human health through robust analytics and innovative clinical trial software. For nearly four decades, we have set the standard in adaptive trial design, leveraging extensive data insights to inform strategy throughout every phase of drug development and commercialization. Our mission is clear: accelerate drug development, enhance success rates, and deliver better patient outcomes. With a comprehensive suite of services from innovative trial design to end-to-end biometrics and real-world evidence, our specialized, multidisciplinary team ensures optimal strategies for preclinical research, trial execution, market access, and reimbursement. Headquartered in Cambridge, Massachusetts, Cytel has a global presence with over 2,000 employees across North America, Europe, and Asia. Learn more about how Cytel is harnessing the power of data to advance human health at www.cytel.com.

CytoTronics is commercializing technology emerging from the Harvard University labs to bring unique insights to drug discovery. A revolutionary approach to studying cell biology, powered by microchips.

Echosens is a healthcare technology company that specializes in non-invasive diagnostic tools for assessing liver health.

Elucid is a Boston-based medical technology company using histology-validated software to provide physicians with a cost-effective means to optimize treatment decisions for patients with cardiovascular disease. Advanced clinical insight from Elucid's CTA analysis equips physicians with critical information designed to enable precision medicine. Elucid is the first non-invasive software to quantify atherosclerotic plaque characteristics compared to histopathology, including Lipid Rich Necrotic Core. The company has published studies for its derivation of fractional flow reserve (FFRct) based on the vasodilative capacity of the vessel wall. Elucid's unique information informs improved treatment decisions by physicians leading to better patient outcomes, improved quality of care, and reduced healthcare costs.

Endpoint Clinical is an interactive response technology (IRT®) systems and solutions provider that supports the life sciences industry. For the past decade, our customer-obsessed team of professionals has continuously evolved our suite of technologies to help Sponsors achieve clinical trial success. Our dynamic IRT solution, PULSE ®, for patient randomization and management, site management, and drug supply management, and our leading-edge clinical supplies management tool, DRIVE, have proven to maximize the supply chain, minimize operational costs, and ensure timely and accurate patient dosing. Endpoint is headquartered in the Boston area, with offices across the US, EU, and Asia.

GI Windows Surgical is a clinical-stage company engineering less invasive solutions for surgeons and patients.

Growth Curve Bio is a company that provides the newest generation of efficient and reliable Bioscreen systems for automated growth curve analysis.

Haemonetics (NYSE: HAE) is a global healthcare company dedicated to providing a suite of innovative medical products and solutions for customers, to help them improve patient care and reduce the cost of healthcare. Our technology addresses important medical markets: blood and plasma component collection, the surgical suite, and hospital transfusion services. To learn more about Haemonetics, visit www.haemonetics.com.

Invicro is a company in the medical imaging and biotechnology industry that specializes in imaging services for pharmaceutical and life sciences companies.

Lattice Automation provides complete solutions to fundamentally change the way that biological designs are conceived, designed, physically created, and managed. Our technology builds upon state-of-the-art techniques in computer science, electrical engineering, and bioengineering. We're hiring!

Layer Health is a healthcare AI company spun out of MIT and backed by GV (Google Ventures), General Catalyst, MultiCare Health System and Froedtert Health. We are solving the information problem in healthcare.

Matrix Science develops and markets software products which integrate mass spectrometry into bioinformatics. Our interests extend to all aspects of mass spectrometry in the life sciences. Please contact us to discuss: * Developing new applications * Consultancy in mass spectrometry and bioinformatics * Systems analysis and integration Mascot: The trusted reference standard for protein identification by mass spectrometry for 25 years

myBiometry is a platform to remotely monitor and manage patients with chronic conditions using software and biomarker data generated from proprietary sensors. Our initial focus is asthma.

Myolex is disrupting how to measure muscle wasting (and treatment), caused by obesity drugs, aging, and sport injuries. Myolex® EIM is a patented device technology and SaaS data analytics platform that is built to disrupt skeletal muscle measurement by becoming the clinical and wellness standard to aid in the diagnosis and treatment of obesity drug and age-related muscle wasting. Myolex has developed the 1st quantitative, sensitive, painless, portable for home use muscle quality assessment device that is specifically designed to non-invasively, comprehensibly, and precisely detect and monitor single muscle wasting.

While our healthcare system has increasingly embraced virtual health in many areas to accelerate access to care, in-person care for patients with cognitive conditions remains the status quo - but Neuroglee Health is making virtual cognitive care a reality. We partner with medical groups to serve as your practice's virtual cognitive care extension – enabling you to provide immediate access to evidence-based care for patients with cognitive disorders and highly coordinated, guided support for the caregivers they rely on. Through our virtual care model, which we developed in collaboration with Mayo Clinic, Neuroglee Health is leaning in to disrupt the status quo. Our partners gain timely access to our team of expert multidisciplinary specialists and powerful, award-winning digital tools: a patient app, care partner app, and clinician dashboard, which optimize patient and caregiver engagement, deliver actionable data-driven insights, and enable coordination across the patient's extended care team. When combined, Neuroglee Health helps patients improve cognition, enhance quality of life, and prolong patient independence, while reducing provider and caregiver burnout. We are on a mission to improve the lives of individuals with cognitive conditions and their loved ones. Join us at www.neuroglee.com.

OmniGuide's corporate culture has grown from the roots of an innovative idea from MIT to a global company that has successfully adapted to changes in the market. INSPIRATION Our purpose is to help reduce complications, every day. We achieve this with our creative energy and enthusiasm for fresh ideas. Our motivation is to continually remind ourselves that when we get up in the morning, patients who need our therapies are counting on us. EXCELLENCE The pursuit of excellence lies at the heart of everything we do. We are builders, redefining what it means to support great outcomes. We have the courage to think different and will ensure that OmniGuide remains committed to ideas that benefit patients and their outcomes.

Ovation is a leading provider of genomic data for the life sciences industry. We are dedicated to supporting the advancement of precision medicine and offer access to a wide range of high-quality, consented genomic data linked to diverse, longitudinal phenotypic data at scale. Our data allows researchers to identify and validate biomarkers, discover new targets and understand resistance mechanisms in various populations. Our cloud-based LIMS system allows clinical labs to easily adopt innovative molecular tests, while also transforming samples into valuable research-grade data across various disease areas. Learn more at www.ovation.io.

Paradigm4 is a pharmaceutical and biotechnology company that offers the REVEAL analytical solutions platform for finding druggable targets quickly, validated by global pharmas and biotechs.

Rapid Reliable Results COVID testing has shined a light on a major bottleneck in the laboratory workflow for accessioning samples, decapping of the samples, and movement of the samples into high throughput assay workflows. Rhinostics offers a simple and elegant solution that can remove time and significant labor, allowing laboratories to move larger number of samples through their laboratories at a lower cost, lower error rates, and with time savings. Rhinostics is revolutionizing sample collection with comfortable, automatable, rapid solutions that concentrate samples that save time, costs, and improve assay sensitivity. The polypropylene anterior nares (nostril) collection device is comfortable and easy for self-collection or in the clinic. It is connected to a threaded cap that can be automatically decapped using the Hamilton Lab Elite instrument. The samples can be shipped dry (RT-PCR does not require live virus so viral transport media (VTM) is not required. The entire 96 well plate of vials can be simultaneously scanned through a 2D barcode on the bottom of the collection vial and the automated decapper robot can be connected to other liquid handling systems and linked into the high throughput assay workflow.

SCARLETRED is the worldwide leader in standardized skin imaging and AI powered objective skin analysis. We develop and deliver cutting edge software products and services to biopharma-, biotech- , cosmetics companies, clinical research organisations and health care experts. Our certified, ICH-GCP and EU-GDPR compliant mobile medical device software Scarletred® Vision is the first digital solution solving the problem of lacking standardization and subjective visual skin assessment in pre-clinical, clinical, and post-marketing studies. The highly scalable software platform works infrastructure as well as location independent and enables on-site and home-based monitoring of dermatologic disease as well as digital analysis of skin drug related effects. It it easy to use and reduces development time and opportunity cost in clinical RnD projects. Our digital Products and Services are delivered worldwide from our offices in Europe and USA via flexible Software as a Service (SaaS) agreements.

Scilligence is a leading innovator of cross-platform, mobile cheminformatics and bioinformatics software solutions. Its informatics tools have been widely adopted by pharmaceutical, biotech, and chemical industries, universities, research institutes, and government agencies. Scilligence's proprietary technologies address three main areas of R&D informatics needs: knowledge management and collaboration; project, workflow and material management; and knowledge mining of unstructured data. What makes the Scilligence platform different: -Powerful integration components for internal and external collaborations -A single platform supporting both small molecules and macromolecules -Truly designed for any device, browser, and platform -Absolutely no Java dependency -Fully supports HELM (Hierarchical Editing Language for Macromolecules) notation (Scilligence developed the JavaScript HELM Editor for Pistoia Alliance) -Developed completely by Scilligence allowing complete configuration and customization unique to each company, organization, or institution -Flexible workflow engine to enable process control and ease system integration -Cost effective in deployment and maintenance -Collaboration, workflow, and Project Management Platform -Connection to Equipment and Devices, Barcode Scan. Products: Scilligence ELN: Cross-Platform Electronic Lab Notebook for Chemistry and Biology RegMol: Cross-Platform Registration & Assay Database for Biologics, Small Molecules, and conjugates such as ADCs Scilligence Inventory: Cross-Platform Inventory System for Life Science R&D Scilligence PMF: Project, Workflow and Customer-Relationship Management System for Life Science R&D Scilligence SDMS: Cross-Platform Scientific Data Management System Scilligence CSM: Clinical Sample Management LIMS: Laboratory Information Management System Focus: Data Analytics and Ideation QMS: Quality Management System TouchMol4Office: Enables Cheminformatics and Bioinformatics in Microsoft Office

Scitara is a global provider of laboratory-specific, cloud-based software solutions for the life sciences and other science-based industries. Our solutions are powering the digital transformation of scientific laboratories by enabling them with modern lab data connectivity infrastructure and tools to accelerate science.​ Scitara DLX allows plug-and-play connectivity between any device, instrument, application, informatics system, web service or lab resource, using our connector technology, automation of workflows, task notifications, and bi-directional data exchange through our powerful and easy-to-use orchestration engine, compliant transformation of data in-flight using our transformation tools and libraries, and capture, monitoring, and analysis of all data transactions using our monitoring capabilities​. Scitara's lab informatics services are rooted in our deep laboratory domain experience, technology skills, and a global delivery model – allowing us to deliver services such as Scitara DLX platform deployment, validation, lab computing and cloud integration services to the highest standards of quality, capability and compliance. Scitara is Hiring! Please see our website for more information.

SpectraWAVE, located in Bedford, Mass., is a privately held medical device company founded in 2017 to provide unrivaled optical and computational insights to improve the treatment and outcomes for patients with coronary artery disease (CAD). CAD, the buildup of plaque in the wall of the arteries that supply blood to the heart, affects 18.2 million adults age 20 and older. In CAD patients that undergo percutaneous stent placement, it is estimated that one in five patients experience adverse events within two years. SpectraWAVE’s state of the art HyperVue™ Imaging System combines next generation DeepOCT™ images and near infrared spectroscopy (NIRS) with workflows optimized for the cardiac catheterization lab. The HyperVue Imaging System is intended for the imaging of coronary arteries and is indicated in patients who are candidates for transluminal interventional procedures. The NIRS capability of the system is intended for the identification of patients and plaques at increased risk of major adverse cardiac events. For more information and complete indications for use, please visit www.spectrawave.com.

Founded in 2022 and headquartered in Boston, Stellaromics is revolutionizing biomedical research with its proprietary technology, unraveling complex 3D transcription and translation patterns within native biological tissue. At the forefront of their innovation is STARmap (Spatially-resolved Transcript Amplicon Readout mapping), their flagship product. STARmap empowers researchers to uncover gene expression patterns within intact tissue, facilitating the pinpointing of treatment targets and bolstering biomedical investigations. Stellaromics is currently in the advanced stages of developing its Plexa™ suite of products, meticulously crafted to empower researchers and clinicians in the creation of intricate cellular maps, thereby amplifying our comprehension of various diseases. For comprehensive details, we invite you to explore our website at stellaromics.com. Join us in shaping the future of biomedical research.

Sunflower Therapeutics is a unique biotechnology start-up focused on dramatically reducing the time and cost to develop and manufacture biologics for patients around the world. With a genetically-optimized host, data-driven process development, and a novel, ‘right-sized’ manufacturing unit, the experienced Sunflower team is creating an efficient, patient-centered, end-to-end drug production platform that we plan to deploy worldwide.

Syncell is a life science tools company revolutionizing proteome and biomarker discovery. Imagine that you have a subcellular “pickable” microscope to let you isolate and identify proteins at a specific location you like under the microscope. Syncell’s groundbreaking Microscoop platform enables hypothesis-free subcellular spatial proteomics with high sensitivity and specificity. Researchers are able to use Syncell Microscoop to discover proteins novel at specific locations of interest from cell and tissue samples. This pioneering technology revolutionizes how novel molecular mechanisms can be identified and how novel biomarkers can be revealed for diseases.

TriNetX is a global network of healthcare organizations and life sciences companies driving real-world research to accelerate the development of new therapies. Through its self-service, HIPAA, GDPR, and LGPD-compliant platform of federated EHR, datasets, and consulting partnerships, TriNetX puts the power of real-world data into the hands of its worldwide community to improve protocol design, streamline trial operations, refine safety signals, and enrich real-world evidence generation.

Valo is a technology company built to transform drug discovery and development using large-scale data and AI-powered computation. Valo aims to ful­ly inte­grate human-cen­tric data across the entire drug devel­op­ment life cycle into a sin­gle uni­fied archi­tec­ture, there­by accel­er­at­ing the dis­cov­ery and devel­op­ment of life-chang­ing drugs while simul­ta­ne­ous­ly reduc­ing costs, time, and fail­ure rates. The company’s Opal Com­pu­ta­tion­al Plat­form™ is an end-to-end drug dis­cov­ery and devel­op­ment plat­form with a uni­fied archi­tec­ture designed to trans­form data into valu­able insights that may accel­er­ate dis­cov­er­ies and enable Valo to advance a robust pipeline of pro­grams, ini­tial­ly focused on car­dio­vas­cu­lar meta­bol­ic renal, oncol­o­gy, and neu­rode­gen­er­a­tive dis­ease.

VideaHealth is on mission to transform dentistry through artificial intelligence. Rooted in AI research conducted at Harvard and MIT, VideaHealth’s FDA-cleared dental AI platform is proven to increase diagnostic accuracy, grow treatment plan values, and improve case acceptance rates. With the largest and most diverse data set in the market, VideaHealth is the partner of choice for the nation's leading DSOs - and is trusted by dentists, hygienists and patients. Backed by leading venture capital firms Spark Capital, Zetta Venture Partners and Pillar VC, VideaHealth is headquartered in Boston.