List of Small Molecule Pharmaceuticals Companies in Minnesota - 14

ANI Pharmaceuticals, Inc. (Nasdaq: ANIP) is a diversified biopharmaceutical company serving patients in need by developing, manufacturing, and marketing high quality branded and generic prescription pharmaceutical products, including for diseases with high unmet medical need. Our team is focused on delivering sustainable growth by scaling up our Rare Disease business through the successful launch of our lead asset, Purified Cortrophin® Gel, strengthening our generics business with enhanced research and development capability, innovation in established brands and leveraging our U.S. manufacturing capabilities. For more information, please visit our website www.anipharmaceuticals.com.

Birchwood is a healthcare company that offers incontinence and wound care products to healthcare professionals and patients.

Celcuity is a clinical stage biotechnology company that discovers previously undetectable cancer drivers and develops drugs to treat them.

Courante Oncology is a full-service clinical research provider specializing in oncology product development. We offer a wide range of clinical trial management and support services to the pharmaceutical and medical device industries, including project management, clinical site monitoring, quality assurance, and medical writing servies. We believe the challenges of oncology clinical trials require a research team that is uniquely experienced and trained. Our strength lies in our collective experience and our ability to adapt to and meet our clients' specific research needs.

Humanetics is a privately held, clinical stage pharmaceutical company located in the Minneapolis metropolitan area. Our lead candidate, BIO 300 is being developed for multiple clinical uses with a primary focus on improving treatment of solid tumor cancers. BIO 300 is being developed as an agent to both sensitize tumor cells to enhance radiation treatment efficacy and to protect normal tissues from harm. Thus, reducing common treatment related side effects such as radiation induced pneumonitis, erectile dysfunction, mucositis and xerostomia. BIO 300 is also under development for inflammatory lung diseases with an immediate focus on mitigation of pulmonary injury due to COVID-19. A recent contract from NIAID will fund a phase 2 study on BIO 300 in recovering COVID patients in an effort to stem progressive long-term lung complications, such as fibrosis. BIO 300 was licensed from the US Department of Defense, where it was originally developed to prevent injuries associated with ionizing radiation. This program is still underway with a focus on prevention of acute radiation syndrome as well as lung injury. For more information about Humanetics, please visit our corporate website at www.humaneticscorp.com.

IGF Oncology, LLC Our Mission: IGF Oncology is developing novel cancer drugs that have better efficacy and lower side effects than existing cancer chemotherapy drugs.

InSitu Biologics is an emerging biotech company focused on development of a multi-phase prolonged release drug delivery platform for localized treatment of pain, cancer, and infection. We use disruptive technology to address unmet needs in the pain management and drug delivery markets.

Lifecore Biomedical is a full-service contract development and manufacturing organization (CDMO) that partners with pharmaceutical and biotech companies to develop and deliver vital and complex injectable therapies. We're also a manufacturer of premium sodium hyaluronate. From formulation to commercialization, we have everything it takes to move your project to the next level, making progress possible for our partners, people and most importantly, patients. Working from state-of-the-art facilities, our people are subject matter experts, our capabilities customized, our processes and systems qualified and our infrastructure optimized to meet your most sophisticated requirements regardless of scale. Our expertise is in drug products that are challenging and difficult to formulate, sterile filter, and aseptically fill. We've been the global leader in pharmaceutical-grade sodium hyaluronate (NaHy) for nearly 40 years. Leveraging this experience alongside deep expertise and capabilities in highly viscous solutions, we create tailored solutions that solve your drug development challenges across the entire development and manufacturing lifecycle. Our capabilities: Sterile Injectable Development - Formulation Development - Sterilization Development - Process Development - Analytical Services & Stability - Engineering Services - Validation Services Sterile Injectable Manufacturing - Sterilization - Aseptic Filling - Packaging - Analytical Services & Stability

Panbela Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing disruptive therapeutics for urgent unmet medical needs. The company's current focus is on the treatment of urgent unmet medical needs.

Peytant Solutions, Inc. (PSI) is a medical device company, incorporating Regenerative Human Biomaterial   with  absorbable and alloy implant technologies. Our percutaneous, biologic AmnioStent...

Our mission at Predictive Oncology is to change the landscape of oncology drug discovery and enable the development of more effective therapies in the treatment of cancer. By harnessing the power of machine learning, scientific rigor and biologics, we can improve the probability of success and advance drug compounds with a higher degree of confidence. We invite you to follow us to stay up-to-date about our latest developments.

Since 1989 ProMed has been recognized as a leading Contract Manufacturer of complex, intricately designed molded silicone and plastic components and assemblies for highly regulated industries. ProMed's expertise lies in applications for short-term and long-term implantable devices, drug-releasing combination devices, and specialized manufacturing for aerospace, defense, and automotive applications. We collaboratively work with our customers from prototype through production, providing over 30 years of experience related to design for manufacturability, material selection, tooling/fixturing, process development, manufacturing, and other value-added services that result in cost-effective solutions with superior quality. With four facilities spanning more than 134,000 sq/ft of office, laboratory, and Class 7 Manufacturing space, ProMed's in-house services include tooling design and manufacturing, quick turn prototyping, injection and transfer molding of components, micro molding of tightly tolerance components, insert over molding, advanced material blending of specialty additives, automated assembly, testing support for drug delivery and combination devices, as well as customized packaging services.

Rion is a clinical-stage regenerative medicine company focused on developing innovative exosome therapeutics that are clinically impactful, accessible, and practical for any patient, anywhere. Rion has developed Purified Exosome Product (PEP), an innovative biologic platform that optimizes the therapeutic power of exosomes for regenerative medicine.

SpineThera designs and develops sustained-release, injectable drugs to meet the unique safety requirements for administration in and near the spine. Our proprietary drugs offer patients and physicians new treatment options that reduce risk, improve outcomes, and manage overall treatment costs in markets with few or no approved drugs.