List of Small Molecule Pharmaceuticals Companies in Michigan - 16

At Ambient Biosciences, we are dedicated to being a true partner in your success. We bring the same spirit of versatility, transparency, and innovation to our customer relationships as we do to our technology. Our approach is to take the mystery out of biomolecule stabilization, making it an accessible and collaborative process that empowers you to feel confident about your products and assays.

Arbor Assays is the first employee-owned life sciences company and is dedicated to advancing scientific discovery by providing innovative and reliable assay solutions. Our mission is to equip researchers and scientists worldwide with high-quality scientific tools and support their objectives with unparalleled customer service. Arbor Assays strives to be a trusted partner to our customers through our commitment to quality, integrity, and collaboration. As employee-owners, we are driven not by investor demand, but rather by a shared sense of responsibility to each other, our customers, our community, and our planet.

Bryllan is a contract manufacturing company that specializes in producing potent and cytotoxic compounds meeting US FDA and global regulatory standards.

Corium is a commercial-stage biopharmaceutical company that is leading the development and commercialization of central nervous system (CNS) healthcare therapies that provide clinicians with important treatment options for patients, their families, and their caregivers. Collaborating with some of the world's largest pharmaceutical and consumer product companies, we have a track record and depth of experience in taking products from concept, through development, to manufacturing and final commercialization.

Official LinkedIn page for Esperion. At Esperion, we discover, develop, and commercialize innovative medicines to help improve outcomes for patients with or at risk for cardiovascular and cardiometabolic diseases. The status quo is not meeting the health needs of millions of people with high cholesterol – that is why our team of passionate industry leaders is breaking through the barriers that prevent patients from reaching their goals. Providers are moving toward reducing LDL-cholesterol levels as low as possible, as soon as possible; we provide the next steps to help get patients there. Because when it comes to high cholesterol, getting to goal is not optional. It is our life’s work. For more information, visit esperion.com and esperionscience.com and follow us on X at twitter.com/EsperionInc. Community guidelines: https://bit.ly/3vLCGdO Certified Great Place To Work®

Small Molecules, Contract Manufacturing

Impact Analytical is a compliance services company that specializes in analytical testing for medical devices, including material composition analysis and contaminant investigation.

Developing novel serpin-based therapies for the treatment of fibrosis and fibroproliferative disorders.

ONL Therapeutics (ONL) is a clinical-stage biopharmaceutical company committed to helping patients see the future. Our mission is to develop innovative therapeutics to protect and improve the vision of patients with a range of retinal disease and conditions. By advancing a breakthrough technology designed to prevent the death of key retinal cells caused by the activation of the natural Fas pathway, ONL is pioneering an entirely new approach to preserve sight. It is the first and only company focused on preventing Fas-mediated death of key retinal cells, which is a root cause of vision loss, a leading cause of blindness and an unaddressed medical need. ONL’s lead therapeutic candidate, ONL1204, is a first-in-class small peptide Fas inhibitor designed to protect retinal cells from both death and inflammatory signaling pathways. ONL1204 Ophthalmic Solution is being developed for the treatment of retinal detachment, an acute condition for which the company has been granted orphan drug designation by the FDA. In addition, the company is currently developing ONL1204 in geographic atrophy associated with age-related macular degeneration, glaucoma, and other acute and chronic indications.

Penrose TherapeuTx is a U.S.-based pharmaceutical company focused on developing innovative small-molecule therapies for the treatment of advanced cancers. The company also develops small-molecule therapies to treat cancer and has prominent researchers and leaders in the field as part of its scientific advisory board and executive team.

Rockwell Medical is a fully-integrated biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD) with innovative products and services for the treatment of iron replacement, secondary hyperparathyroidism and hemodialysis. Rockwell’s new innovative therapy Triferic is the only FDA approved drug indicated to replace iron and maintain hemoglobin in hemodialysis patients suffering from anemia. Via dialysate during each dialysis treatment, Triferic replaces the 5-7 mg iron loss that occurs in all patients, maintaining their iron balance. Unlike IV iron products, Triferic binds iron immediately and completely to transferrin (carrier of iron in the body) upon entering the blood and is then transported directly to the bone marrow to be incorporated into hemoglobin, with no increase in ferritin (stored iron and inflammation) and no anaphylaxis, addressing a significant unmet need in overcoming Functional Iron Deficiency (FID) in ESRD patients. Visit www.triferic.com to view the Triferic mode-of-action (MOA) video and for more information. Rockwell’s FDA approved generic drug Calcitriol is for treating secondary hyperparathyroidism in dialysis patients. Calcitriol (active vitamin D) injection is indicated in the management of hypocalcemia in patients undergoing chronic renal dialysis. Rockwell is also an established manufacturer and leader in delivering high-quality hemodialysis concentrates/dialysates to dialysis providers and distributors in the U.S. and abroad, with three manufacturing/distribution facilities located in the U.S. Rockwell’s products are used to maintain human life by removing toxins and replacing critical nutrients in the dialysis patient’s bloodstream. Rockwell’s exclusive renal drug therapies support disease management initiatives to improve quality of life and care of dialysis patients and are intended to deliver safe and effective therapy, while decreasing costs and improving patient convenience.

SciTech Development is a Specialty Pharmaceutical Company dedicated to advancing cancer treatment through safer drug delivery. They are based in Michigan, USA and are known for their innovative drug delivery platform SDP that engineers new therapeutics for better & broader clinical applications.

We are a clinical-stage biopharmaceutical company developing an oral small molecule for the treatment of thyroid eye disease (TED). Our team consists of highly experienced drug developers, supplemented by global experts through our Scientific Advisory Board.

ADVANCING HEALTHCARE WITH HEART CREATE YOUR FUTURE, AND OURS Here you grow your own way, you create to innovate, and learn as you go, alongside like minds who share the same commitment to the future of healthcare. We are proud to have launched global development programs to help our associates shape their careers alongside the future of healthcare. ENJOY A REWARDING AND MEANINGFUL CAREER As a team, we make a real difference to the health and wellbeing of our patients today, and leave a lasting legacy for tomorrow. Your time is dedicated to innovation, problem solving, teamwork and lifelong learning, as an integral part of our ever-curious, always committed, continually collaborative environment. We foster a growth mindset culture, embracing mistakes as an opportunity to learn, and celebrating the small wins along the way, so we can all grow together. FOR TERUMO, FOR EVERYONE, EVERYWHERE Whatever you do – marketing, engineering, sales or manufacturing – our teams look out for one another, respect and support each other in achieving our goals, and we value diversity and inclusion, empowering everyone to bring their authentic self to work. If you’re ready to advance healthcare with heart, we look forward to hearing from you.

Tetra Therapeutics is a clinical stage biotechnology company developing a portfolio of therapeutic products. Tetra designs drugs to treat memory loss and cognitive impairment by improving how the brain processes and stores information. The company is focused on treating cognitive impairment and memory loss by improving brain function.

Vestaron Crop Protection is an ag technology company dedicated to providing our customers with the powerful solutions they need to meet the growing challenges of modern agriculture. Founded in 2005 and headquartered in Durham, NC (USA), we are producing a pipeline of powerful insecticides with new modes of action based on peptides modified from the venom of spiders and other venomous animals. Naturally soft on pollinators, beneficials, and local biodiversity, our innovations have earned recognition from the Crop Science Awards and the EPA’s Green Chemistry Challenge. In 2024, we became the first agriculture and food company inducted into the Global CleanTech 100 Hall of Fame. Our first product, SPEAR® LEP, is proven on more than 650,000+ acres and continues to gain market share in North America. Recently, SPEAR LEP has been approved for Emergency Use Authorization in several EU countries as a desperately needed solution to help farmers combat the destructive impact of tomato leafminer (Tuta absoluta) infestations which cause substantial yield and economic losses for farmers across the Mediterranean region of Europe. In 2024 the Environmental Protection Agency (EPA) approved our second novel-acting insecticide, BASIN®. Vestaron Crop Protection: Unconventional, by nature.