List of Repurposed/505(b)(2) Drugs Companies in Israel - 3

Concenter BioPharma - a patented, unique, proven, novel platform of drugs with 3 modes of action. We are advancing a pipeline of products that demonstrate vast potential in addressing multi­billion markets for treating a range of diseases (that require common MoA’s – our Platform). We will become a global specialty biopharmaceutical company focused on people and providing innovative therapies for them. Our Platform will enable us to jump quickly from one product to another without having to rediscover and recreate an underlying technology for each product. we are committed to developing and delivering therapies that work harmoniously with the human body and advance the treatment landscape for people living with life-threatening diseases.

NurExone Biologic is developing a revolutionary biological exosome based technology drug platform to treat damage in the Central Nerve System. The breakthrough exosome-based technology was proven in preclinical studies to have the potential to treat spinal cord injuries.

SciSparc Ltd. (NASDAQ: SPRC) is a specialty clinical-stage pharmaceutical company led by an experienced team of senior executives and scientists. Our focus is on creating and enhancing a portfolio of technologies and assets based on cannabinoid pharmaceuticals. With this focus, the Company is currently engaged in the following drug development programs based on THC and/or non-psychoactive cannabidiol (CBD): SCI-110 (formerly THX-110) for the treatment of Tourette syndrome and for the treatment of obstructive sleep apnea; SCI-160 (formerly THX-160) for the treatment of pain; and SCI-210 (formerly THX-210) for the treatment of autism spectrum disorder and epilepsy.