List of Regenerative Medicine Companies in Pennsylvania - 12

Accelerated Biosciences Corp. is commercializing human trophoblast stem cells isolated from the trophectoderm of embryos from women with ectopic pregnancies. hTSCs are ethically sourced and have immune-privileged characteristics. It is an abundant and dynamic pluripotent stem cell platform for basic research, disease modeling, toxicology, drug discovery, and cell therapy.

Allevi Develops 3D printers fof bioinks. Bioinks are materials that mimic an extracellular matrix environment to support the adhesion, proliferation, and differentiation of living cells. From GelMA to Collagen and from Hyperelastic Bone to Graphene, Allevi offers the widest range of material capabilities.

Aposcience AG aspires to improve the health of patients in need of regenerative medicine by commercially exploiting the therapeutic potential of secretomes derived from white blood cells (PBMCs) isolated from peripheral blood. PBMCs are currently a waste product of all blood transfusion units.

Cook MyoSite is on a mission to make regenerative medicine a part of everyday medicine. As an industry leader in muscle cell technology, we’re establishing new paradigms for muscle-related disorders. Established in 2002, Cook MyoSite was created to guide the Cook Group organization into the expanding world of cellular technologies. We’re proud to be a part of the vibrant medical community in Pittsburgh, Pennsylvania.

Advancing regenerative medicine through the development of a natural biomaterial that restores mother nature’s template to treat disease and injury. ECM scaffolds, in solid form, have been successfully used in more than 10 million human patients to repair a variety of body systems such as musculoskeletal tissues, cardiovascular structures, and non-healing skin wounds, among others. These products have all received FDA clearance. ECM Therapeutics'​ patented ECM hydrogel technology allows for expanded, less invasive applications in multiple disease areas. The first clinical product, EsophaGel, treats Barrett’s esophagus, a precancerous condition that currently has no effective therapy.

Advancing the Science of exosomes and precision Growth Factors, Exocel Bio strives to be the leader in the regenerative aesthetic industry by leveraging our nanoparticle technology platform, and is dedicated to the pursuit of making anti-aging a reality. EXOVEX is a skin post Laser or Microneedling treatment packed with exosomes and precision growth factors that have been formulated to accelerate recovery and enhance efficacy by improving the appearance of hair, fine lines, wrinkles, skin tone and texture.

Imagine Pharma is a biotechnology company focused on three distinctive platforms: oral delivery, regenerative and therapeutics. Each platform has first-in-class programs that address multiple disease states in large underserved markets.

LyGenesis is a biotechnology company with an organ regeneration technology platform enabling a patient’s lymph nodes to be used as bioreactors to regrow functioning ectopic organs. LyGenesis’ lead preclinical program is focused on liver regeneration for patients with end stage liver disease. Other therapeutic targets for organ regeneration include the thymus, pancreas, and kidney. Privately held, LyGenesis is headquartered in Pittsburgh, Pennsylvania.

Prolifagen Therapeutics is a biotech startup dedicated to the prevention of heart failure in patients with large myocardial infarcts. The company is focused on cardiac regeneration based on microRNA technology.

Swan NeuroTech is a Pittsburgh-based startup developing biodegradable implants for peripheral nerve injuries.

INNOVATIVE BONE GRAFTS BASED ON IMPROVED BIOACTIVE GLASS Synergy has identified an optimal bioactive glass particle with a spherical shape and a biomodal size range that has been shown to significantly improve bone healing. Synergy's BioSphere® particles have been engineered to maximize the bone healing potential of bioactive glass. Synergy Biomedical is a privately-held medical device company focused on bringing biomaterial based products to the orthopedic and spinal surgery markets. Synergy's BIOSPHERE Technology represents an innovative approach to advancing bone graft technology, and improving bone healing and patient outcomes. Synergy Biomedical welcomes inquiries from independent sales distributors with an understanding of orthopaedic and spinal surgery. We are looking for distributors with a proven track record who are willing to grow our bone graft market. Please visit our website for more information: www.synergybiomedical.com

XyloCor Therapeutics is a development-stage, biotechnology company dedicated to developing first-in-class gene therapies for patients with unmet medical need in cardiovascular disease.