List of Personalized Medicine Companies in Singapore - 5

4baseCare, an Illumina-backed Company* headquartered in Singapore, is engaged in developing cutting-edge Precision Oncology Solutions using Advanced Genomics and Next-Gen digital health technology. Taking into consideration that the clinical outcome could significantly vary across different populations, we have developed a unique set of indigenous comprehensive cancer gene panels that enables oncologists to choose the optimal precision therapies for their patients. Our coveted 🧬genomic testing portfolio assesses the tumour genomic alterations by NGS from Tissue or Liquid biopsy for Somatic Mutation Analysis and Germline Mutation Testing for Hereditary and Familial Cancer from peripheral blood to personalize patient care in Oncology. 4baseCare is backed by a highly experienced Advisory board who are leaders in genomics and technology. Among them is Lip Bu Tan, Chairman of Walden International and advisor to Yali Capital, which has invested in 4baseCare. Also on the board is Francis deSouza, a Silicon Valley tech veteran and former CEO of Illumina, who brings over 30 years of expertise in genomics, technology, and healthcare. Milestones - 4baseCare’s journey has been marked by significant milestones in both funding and growth. The company has raised $6 Million in Series A funding led by Yali Capital with participation from Mathew Cyriac. In March 2021, 4baseCare had raised $2 Million in led by Mount Judi Ventures, growX ventures, Season Two Ventures, First In Ventures, and other angel investors. 4baseCare’s test has made a significant impact in Southeast Asia, with over 10,000 cancer patients taking the test. 4baseCare has collaborations with more than 300 oncologists in India. This growing network with oncologists and leading hospitals in India ensures that more patients are able to opt for personalized cancer care.

Entrepreneur led and science backed, 𝐈𝐍𝐄𝐗 𝐈𝐧𝐧𝐨𝐯𝐚𝐭𝐞 is one of Asia’s fastest growing molecular diagnostics developers and medical laboratory operators. Founded by veteran maternal fetal medicine specialists, INEX is uniquely positioned to identify and address clinically unmet needs within the fetal health and women’s oncology landscape, with a broad commercial portfolio of validated tests and 49 key patents. Through our wholly owned subsidiary iGene Laboratory Pte Ltd, INEX operates a state of the art Next Generation Sequencing Laboratory that provides diagnostic testing, clinical research (CRO) and infectious testing services. The company has been recognised globally with a number of accolades and awards including from Frost & Sullivan, the World Intellectual Property Organisation (WIPO), The Straits Times – Singapore’s Fastest Growing Companies, the Financial Times ranking of 500 of Asia Pacific’s Fastest Growing Companies and the Business Times KPMG Enterprise 50 award, recognising the 50 most enterprising Singapore companies. For more information please visit: www.inex.sg

Invitrocue Limited is a biotechnology company based in Singapore, founded in 2012. The company specializes in advanced 3D cell-based models and personalized oncology solutions, operating globally with a presence in Australia, China, Hong Kong, and Germany. Invitrocue offers a range of services, including the Onco Patient-Derived Organoid (PDO) Test, which uses patient-derived tumor cells to tailor cancer treatments. Their 3D CelluSponge Technology provides a scaffold-based system for drug metabolism studies, toxicology assessments, and infectious disease modeling. Additionally, they offer customized services for disease modeling and assays, focusing on respiratory diseases and liver infections, as well as digital pathology and medical imaging to support drug testing and organoid analysis. The company collaborates with industry networks to develop preclinical models, enhancing drug discovery and therapeutic outcomes.

Multidimensional Health Intelligence Platform for digital powered care delivery Mesh Bio is a fast growing digital health startup focused on addressing the growing challenges in care delivery. Mesh Bio develops AI powered clinical decision support, analytics and automation solutions for healthcare providers to transform healthcare delivery with digital solutions. At Mesh Bio, we actively build an environment for personal excellence and career growth. We encourage diversity of experiences/backgrounds and want team members to thrive in their domain of professional expertise.

Mirxes is a Singapore-headquartered biotechnology company whose mission is to save lives through early, actionable, and personalized diagnoses across the care continuum. We are Asia-centered, starting with Southeast Asia, and have global ambitions. We have research, development, manufacturing, and clinical diagnostic operations in Singapore, USA, Japan, and China. We have sales and distribution networks worldwide. Our flagship product is GASTROClear, the world’s first molecular blood test for early detection of gastric cancer, able to detect around 90% of patients with Stage I and II cancers. We continue to build a comprehensive cancer portfolio with early detection tests for lung and thyroid cancer (2022), colorectal and breast cancer (2023), liver and ovarian cancer (2024). We are concurrently building a precision oncology portfolio to provide clinical insights for the complete patient journey. MiRXES was spun off from A*STAR’s Bioprocessing Technology Institute in 2014 to commercialize an industry-leading qPCR-based technology for microRNA detection. Our ID3EAL discovery tool and workflow has been adopted by top academic and industry partners globally and is backed by the world’s first industry standard for microRNA-base diagnostics. Our versatile platform technology and capabilities have broad applications in the discovery of biomarkers and diagnosis of diseases. We are starting with early cancer detection, but we will also be addressing unmet clinical needs in cardiovascular, metabolic, and infectious diseases. We responded to COVID-19 by leveraging our capabilities to mass produce and distribute over 5 million units of the Fortitude COVID-19 RT-PCR test. This made-in-Singapore diagnostic test, developed by A*STAR and Tan Tock Seng Hospital, has been deployed in 13 Singapore hospitals and clinical labs and exported to over 45 countries worldwide. Post-COVID, we will leverage this network to commercialize multi-cancer early detection tests.