List of Personalized Medicine Companies in Maryland - 4

BioMarker Strategies has developed the proprietary SnapPath® Cancer Diagnostics System for predictive tests to guide targeted drug development and treatment selection for patients with solid tumor malignancies. Our mission is to make personalized medicine more of a reality for these patients. SnapPath® is unique in automating and standardizing functional ex vivo profiling to capture the dynamic and predictive signaling information available only from live solid tumor cells. Our PathMAP® Functional Signaling Profiles, created using the SnapPath® system, represent a new class of biomarker tests that are highly predictive of individual response to targeted treatments for solid tumors, because they are based on information available only from live cells. Our business development efforts are directed toward entering into funded collaborations with companies developing targeted therapies for patients with solid tumors. The capabilities of SnapPath® and the Functional Profiles it enables are available for Research Use in preclinical studies in tumorgraft and other model systems, and in early clinical studies to assess pharmacodynamic changes in the solid tumors of individual patients.

CHCFbrain.org is a non-profit organization and advocacy group, centered around neuro-development with focus on long-term solutions. The long-term goals, which are the focus of CHCF , are to promote research to 1) identify the root cause(s) of serious learning disabilities and neuro-developmental delays and disorders with mental health manifestations; 2) develop objective unbiased "blood based" diagnostics; 3) develop curative therapies based on these not yet identified or characterized genetic and epigenetic markers. Hypothesis: A common set of gene(s) are involved in diseases of brain including Alzheimer's, Parkinson's, Autism, learning disabilities & neurodevelopmental delays and serious mental health conditions. Mission Statement: To accelerate research in biomarkers for early diagnosis of high risk conditions that affect brain function and to develop novel targeted curative therapies based on molecular causes of these conditions discovered through epigenetic and genetic research. To provide parents and health care professionals objective tools to support development of children very early on as infants and toddlers based on objective behavioral and psychological assessments. We are born with inherent characteristics that define our personality and who we are. Some of us learn to thrive and some of us struggle to master and learn how to cope with our environment. For the majority of us this is not because we have mental health conditions but it is because we are not equipped to thrive in the environment we live in. We at CHCF believe that each person is very unique. We also believe that in order for our children to thrive emotionally we must have objective diagnostic tools that could identify 1) the optimal thriving environment for each child early on and; 2) how each child can learn critical skill sets to cope with inevitable adverse events in the existing global environment. To do so this requires a new approach in understanding who we are. Please join us!

We develop first-in-class RNA-based therapies, with lead programs in Head & Neck Squamous Cell Carcinoma (HNSCC) and Facioscalpulohumeral Muscular Dystrophy (FSHD). Our approach to drug design revolves around using genomic patient data to create highly tailored therapeutics – the right drug for the right patient. Our proprietary DREAmiR™ platform utilizes genomic and outcome data from thousands of patients to identify underlying genetic changes that cause their disease, and then creates a novel RNA therapeutic that can directly target and fix that genetic abnormality.

Psomagen, Inc., formerly Macrogen Corp, delivers genomic sequencing services to the clinical, academic, and consumer markets. Psomagen's labs are US-based and CLIA and CAP certified. Not only is the company accredited to perform the highest quality Sanger sequencing, Next-Generation Sequencing and Microarray Gene Analysis, it is also networked with Macrogen's worldwide headquarters, stretching its capabilities and capacity across a diverse set of labs around the world. Learn more at psomagen.com.