List of Personalized Medicine Companies in France - 17

Acobiom is specialized in the identification of new Biomarkers and in the development of innovative Diagnostics in Translational Research and Precision Medicine. The company provides also customized services in genomics, transcriptomics, bioinformatics and biostatistics (data science), thanks to its technology platform and its scientific expertise. For more information about Acobiom, please contact the company by email: busdev@acobiom.com, or visit its website: www.acobiom.com.

At Aton, we're building a team of expert companies dedicated to accelerating the progress of tomorrow's therapies. To help deliver the right treatment, to the right patient, at the right time. Aton's Ecosystem – Lifescience platforms united to transform therapies Our platforms are driving a fundamental shift in how medicines are developed. Toward products and services adapted to the patient's biology. Complimentary cutting-edge businesses, with unique technologies and diverse teams of experts. One goal. To accelerate discoveries for the good of patients, medicine, and society. Aton's platforms guide and support life-science businesses to achieve their goals with greater efficiency. Our Strategy We're driven by our ambition to develop tomorrow's therapies. We invest in, guide, support, and develop lifesciences companies with unique technologies. Our strategic investments focus on advancing personalized medicine. We collaborate with the brightest entrepreneurs, to provide flexible and longterm support. To ensure they reach their full potential — to help advance today's and tomorrow's medicines. To transform patient outcomes for good. Many specialists, working as one team, we're constantly moving forward, to take our place at the cutting-edge of medical advancements. We see the future of health. It's safer, targeted and more effective. We understand what it takes to deliver to health and regulatory requirements. Helping make this future a reality.

Bioptimus is a developer of a universal AI foundation model designed to drive advancements in scientific research and biotechnological innovations. Their mission is to build the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovations in biomedicine.

Bio-Xtal is historically a provider of structural biology services. Since twelve years, our know-how in structural biology allowed us to perform projects ranging from domain definition to the structure resolution of protein/ligand or protein/protein interactions by Xray crystallography and NMR. We put an emphasis on monitoring the activity of our targets to ensure the relevance of the structural data we deliver. Our policy is to systematically develop home designed activity assays during our structural biology projects. Mastering eukaryotic and prokaryotic expression systems allows us to supply high quality protein for the needs of your compound screening as well as for structural studies of the selected compound’s complexes, guarantying the coherence of the results obtained on both sides A new key service from of Bio-Xtal is the cytosoluble single chain antibody fragment selection (Cytobody™). These can be raised against any antigen within a very short delay (4 weeks) and are very well expressed in either mammalian or bacteria cells. This allows their expression in Coli for large scale production and expression within mammalian cells for cellular biology applications. The applications of the Cytobodies ranges from the discovery of new druggable sites in multi-domain proteins to immuno-detection, cell imaging, protein purification, and protein stabilisation.

CellProthera, a biotechnological company, has developed a unique therapeutic technique which enables the structural and functional regeneration of severe post-infarctus cardiac lesions. After European and national (FR/GB) authorization was obtained , CellProthera has started its I/IIB clinical trial in Humans.

Corteria Pharmaceuticals - FOCUSED ON THE DEVELOPMENT OF TRANSFORMATIVE THERAPIES FOR THE TREATMENT OF WORSENING AND ACUTE DECOMPENSATED HEART FAILURE Founded in 2021, Corteria Pharmaceuticals is a privately held company developing first-in-class drugs for indications of high unmet medical need, such as heart failure, sarcopenia and obesity subpopulations. Our strategy implies innovative patient stratification and target selection based on human evidence and a better understanding of the disease biology in patients. We are using cutting-edge methods to stratify the patients and identify those who will benefit the most from our treatments. Our focus is on worsening and acute heart failure, right heart failure, sarcopenia (including age-related sarcopenia and obesity-related sarcopenia) and obesity with established complications.

DNA Script was created to revolutionize DNA synthesis with enzymes. Our core R&D efforts have produced innovations in enzyme engineering, surface and nucleotide chemistries, and instrumentation. The integration of these innovations has resulted in SYNTAX™️, the world’s first benchtop DNA printer powered by enzymatic technology. With continued advancement and innovation, we believe DNA Script’s enzymatic DNA synthesis technology is poised to become the engine of genomics research and personalized medicine.

Epigene Labs is creating the intelligence-augmenting solution for precision oncology research and drug development. Designed by cancer scientists for cancer scientists, the company's mCUBE platform accelerates data-driven drug discovery, biomarker identification, and patient selection -- to bring better treatments to patients faster. Based in Paris and Boston, Epigene Labs was initially incubated at the Harvard Innovation Labs and launched in France with the support of prominent European investors. Epigene Labs has partnerships with world-class cancer research institutes and biopharmaceutical companies.

HalioDx utilizes a proprietary set of Immune biomarkers, advanced image analysis technologies and a unique know-how to develop, manufacture and commercialize immune-based diagnostics services and products.

Odimma is a French biotech company with a unique approach in active personalized cancer immunotherapy. Immunotherapy has revolutionized the treatment of many advanced cancers. Despite this amazing achievement, significant clinical benefits are still limited to 10 to 30% of patients. Odimma believes in the future of precision medicine, and leverages recent advances in the field of immuno-oncology to amplify the efficacy of current therapies, improving lives and making each patient unique. By harnessing the ability of the patient’s own immune system to specifically recognize non-self-targets displayed by the tumor, also called neoantigens, Odimma has designed a next-generation personalized immunization platform that brings a sustainable therapeutic solution to fight the most hard-to-treat cancers. Carried by a team of experts and a supportive environment, we are now preparing our upcoming entry in the clinic

AI in the service of precision medicine. We don't perform miracles, just create the tools that enable them. At Okeiro, we develop medical AI solutions that transform the monitoring of transplant patients and those with chronic conditions. Our predictive algorithms, scientifically validated digital biomarkers, convert complex medical data into information directly usable by healthcare teams. This technology allows us to: - Detect early signals of complications or graft rejection - Personalize each treatment for truly proactive care - Intervene before critical symptoms appear Our goal is clear: to tangibly improve patients' lives by equipping healthcare professionals with innovative tools that make a daily difference. In close collaboration with healthcare professionals and pharmaceutical companies, we accelerate the clinical validation of therapeutic innovations to make new treatments more quickly accessible to the patients who need them!

We integrate standard assays on chip (eg. CRISPR, T-cell, cytotoxicity) to accelerate drug discovery from target to validation, and advance preclinical predictivity

One Biosciences leverages the power of single-cell analysis to unlock a new wave of targets and precision medicines for a broad range of difficult-to-treat conditions. One Biosciences is an integrated discovery engine combining a multi-disciplinary team with in-house computational capabilities. One Biosciences is backed by Institut Curie and Home Biosciences.

Orakl Oncology leverages a unique collection of patient tumor avatars that combines biology and clinical data to fuel the therapeutic arsenal to fight cancer. With our platform we partner with oncology players to identify relevant targets and deliver new drugs, faster.

Scipio bioscience had to cease its operations on 18/09/2024. At Scipio bioscience we were passionate about empowering every researcher to discover the molecular mechanisms of life for better health and a sustainable world. Enabling deeper insights into disease understanding, Scipio wanted to boost the access to and increases the pace of discoveries with its Asteria benchtop kit for easy scRNA-seq sample preparation and its Cytonaut intuitive cloud-based data analysis software for biologists and bioinformaticians alike. Scipio provided all researchers with empowered autonomy to embrace the next step in single-cell, working with unaltered transcriptomic data for the highest-quality results and true biological information. Scipio bioscience was housed in the Paris Santé Cochin incubator, located in the celebrated Parisian Cochin Hospital.

Founded in 2017, SeqOne Genomics headquartered in Montpellier, France, is a fast-growing deep-tech company focused on turning genomic data into medically actionable insights in oncology, rare and inherited diseases. SeqOne clinical genomic analysis platform, powered by explainable AI, provides genomic labs and healthcare professionals with best-in-class accuracy, usability, and automation seamlessly across lab technologies. By streamlining complex multi-omics analysis workflows, we pave the way for a new era of personalized healthcare at scale, where genetic testing becomes as routine as traditional blood work, radically enhancing health outcomes for all. The company has won numerous awards, including the iLab award and the ARC Cancer Foundation’s Hélène Stark prize. It has been nominated twice for the prestigious Prix Galien award. Investors include Elaia, IRDI Capital Investissement, Merieux Equity Partners, Omnes, and Software Club.

Pioneer and expert in blood and tissue microbiota, Vaiomer carries out microbiota studies, in the fields of human and animal health, for preclinical and clinical research, CROs, dermocosmetics, nutraceuticals and pharmaceutical / biotech companies. We perform microbiota studies from a very wide variety of biological samples (blood, adipose tissue, biopsies, tumors, and more classically skin, saliva, faeces, etc.): DNA extraction, quantification by qPCR, sequencing metagenomics, Bioinformatics, Biostatistics. Upstream and downstream of the studies: support for the experimental design and the drafting of study protocols, then for the interpretation and valuation of the results. The role of tissue and blood microbiomes in systemic inflammation is studied in a wide variety of pathologies: https://vaiomer.com/microbiome-applications/ Microbiota can interact with compounds. The study of the action of a compound on the microbiota makes it possible to characterize the modulating, protective or toxic effects of the microbiota on the compound, or of the compound on the microbiota. Taking into account variations in the microbiota also makes it possible to derisk the translation from the animal model to humans: it is a new source of biomarkers of the therapeutic response (responders / non-responders). We are an expert multidisciplinary team (Scientific / Microbiota, Molecular Biology, Bioinformatics and Biostatistics), have a unique technology for samples of low bacterial biomass and a molecular biology laboratory that can process samples from infected subjects (COVID , HIV...)