List of Next-Gen Sequencing Companies in China - 12

Amoy Diagnostics (AmoyDx) is a visionary diagnostic company dedicated to transforming the landscape of cancer care. 'Breaking Barriers to Precision Oncology' reflects our commitment to revolutionizing cancer diagnosis and treatment. We are driven by four fundamental values: Innovation in Care, Accessibility and Equity, Collaboration and Partnership, and Integrity and Trust. These values guide our pursuit of developing groundbreaking diagnostic tools and fostering a more equitable, collaborative, and trustworthy approach to oncology. Join us as we pave the way to a future where precision cancer care is a reality for every patient, everywhere.

About Burning Rock Burning Rock Biotech Limited (NASDAQ: BNR), whose mission is to guard life via science, focuses on the application of next generation sequencing (NGS) technology in the field of precision oncology. Its business consists of： 1) NGS-based therapy selection testing for late-stage cancer patients, with the leading market share in China and over 273,000 tissue and liquid-based tests completed cumulatively. 2) cancer early detection, which has moved beyond proof-of-concept R&D into the clinical validation stage. In July 2018, Burning Rock received the first approval for a tumor NGS kit by the National Medical Products Administration (NMPA), which is a significant milestone in the field of in vitro diagnosis in China. Burning Rock’s laboratory has obtained the technical certification of “High-throughput sequencing laboratory” issued by Guangdong Center for Clinical Laboratory, and the CLIA and CAP laboratory quality system certification. The company continues to be committed to the development of innovative and reliable NGS testing products and promoting the development of precision medicine in oncology. 燃石医学（纳斯达克代码：BNR）成立于2014年，公司使命为“用科学守护生命之光”，专注于为肿瘤精准医疗提供具有临床价值的二代基因测序（NGS）。公司业务及研发方向主要覆盖： 1）基于NGS的肿瘤患病人群检测，累计检测样本超过27万例，在中国拥有领先的市场份额； 2）基于NGS的癌症早检，目前已经进入临床验证阶段。 燃石医学于2018年7月获国家药品监督管理局（NMPA）颁发的中国肿瘤NGS检测试剂盒第一证，在体外诊断领域具有里程碑式意义。位于中国广州的实验室通过广东省临检中心颁发的“高通量测序实验室”技术审核，获得美国CLIA和CAP实验室质量体系资质认证；位于美国加利福尼亚州的实验室也已获得CLIA和CAP实验室质量体系资质认证。公司将继续致力于开发创新可靠的NGS检测产品，推动肿瘤精准医疗领域的发展。

Genetron Holdings Limited ("Genetron Health" or the "Company") is a leading precision oncology platform company in China that specializes in cancer molecular profiling and harnesses advanced technologies in molecular biology and data science to transform cancer treatment. The Company has developed a comprehensive product and service portfolio that cover the full-cycle of cancer care from early screening, to diagnosis and treatment recommendations, to continuous monitoring and continuous care.

3/28/24- the completion of its merger (the “Merger”) with Genetron New Co Limited (“Merger Sub”), pursuant to the previously announced agreement and plan of merger, dated as of October 11, 2023 (the “Merger Agreement”), among the Company, New Genetron Holding Limited (“Parent”) and Merger Sub. As a result of the Merger, the Company has become a wholly owned subsidiary of Parent and will cease to be a publicly traded company. Genetron Holdings Limited (“Genetron Health” or the “Company”) is a leading precision oncology platform company in China that specializes in cancer molecular profiling and harnesses advanced technologies in molecular biology and data science to transform cancer treatment. The Company has developed a comprehensive product and service portfolio that cover the full-cycle of cancer care from early screening, to diagnosis and treatment recommendations, to continuous monitoring and continuous care.

GrandOmics focuses on the application of long-read sequencing technology；we developed sequencing solutions for different biology research fields by integrating the advantages of multiple sequencing platforms, including NGS and Long-read Sequencing. GrandOmics also actively engaged in the independent development of bioinformatics software and explore the application of long-read sequencing technology in clinical medicine. In response to the data processing problems of the long read sequencing technology in the application fields of animal and plant genome research, pathogenic microorganism detection, and clinical testing, we have developed NextDenovo, NextPolish, GrandBox, GrandPathogen and other bio-information algorithms and platforms to analysis genomic data. Contact us now at inquiry@grandomics.com. We are so glad to assist your genomics research – we’d love to hear from you!

Founded in 2014, HaploX aims to integrate liquid biopsy technology, gene sequencing, artificial intelligence, big data, and other technologies to improve the management of cancer patients. HaploX's technologies include tools for capturing circulating tumor DNA; extracting and amplifying ultra-low concentrations of DNA from liquid samples; performing tagged sequencing; and managing and analyzing the resulting data. Presently, HaploX's polycentric global distribution include: Shenzhen R & D Headquarter, Third-party Medical Laboratory, GMP Factory, US R & D center and ShangRao International Precision Medical Health Industrial Park. HaploX obtained a certificate of participation from EMQN(The European Molecular Genetics Quality Network) in 2017 and achieved both satisfactory results in two external quality assessment schemes: Lung Cancer(NSCLC)2 and Oncogene panel testing. HaploX possesses the most advanced platforms in the world: Illumina's NextSeqs, HiSeq X Tens, NovaSeq 6000 series and digital PCR. HaploX's throughput is now the second in the world rankings. In December 28th, 2017, HaploX Biotechnology raised $32 million in series A+ round. At the same time, NIVIDA accepted HaploX as a member in Inception program(a program started by NIVIDA in order to support startups that are revolutionizing industries with advances in artificial Intelligence and data science). The firm will continue to develop its sequencing technology, which is capable of detecting circulating tumor DNA for personalized cancer therapy.

SHENTEK is a premier brand dedicated to providing high-quality QC solutions to the biopharmaceutical industry. Our standardized and customized quality control (QC) products cater to various cell species and manufacturing processes. We have successfully supported thousands of customers from R&D stage to product release, including pre-IND, IND and BLA filing. Whether you require ready-made products or tailored solutions, SHENTEK is your trusted partner for your quality control needs.

IASO Bio is a clinical-stage biopharmaceutical company engaged in the discovery and development of novel cell therapies for oncology and autoimmune diseases. Leveraging its proprietary fully human antibody discovery platform (IMARS), high-throughput CAR-T drug priority platform, and proprietary manufacturing processes, IASO Bio is developing a rich clinical-stage pipeline of multiple autologous and allogeneic CAR-T and biologics product candidates. This includes a diversified portfolio of 8 novel pipeline products, as well as IASO’s leading asset, CT103A, an innovative anti-BCMA CAR-T cell therapy under pivotal study for relapsed/refractory (R/R) multiple myeloma (RRMM), which was granted Breakthrough Therapeutic Designation by China’s National Medical Products Administration (NMPA) in February 2021. In addition. The company’s in-house developed fully human CD19/CD22 dual-targeted chimeric antigen receptor (CAR)-T cell therapy, has received two IND clearances from NMPA for the treatment of CD19/CD22-positive relapsed/refractory B-cell non-Hodgkin's lymphoma (r/r B-NHL) and relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) in July 2021.

Founded in 2016, MGI has more than 900 employees, nearly half of whom are R&D personnel. MGI operates in 26 countries and regions and has established multiple research and production bases around the world. MGI develops DNA sequencingand related instrumentation.

Founded in Shenzhen, Salus Biomed specializes in developing high-throughput genetic sequencing platforms and is a world leader in super-resolution spatial omics research platforms, serving both research and clinical applications. With a proven track record and over 100 clients worldwide, Salus Biomed is dedicated to providing a range of cutting-edge instruments and solutions to the sequencing and life sciences industry. This empowers users across various industry and academic research applications.

Innovent Biologics Co is a biopharmaceutical company that focuses on developing innovative biotechnology solutions in the healthcare and pharmaceuticals industry.