Company

About

3Daughters

3Daughters

mansfield, massachusetts, united states

3Daughters is a clinical development company focused on enhancing women’s healthcare through innovative contraceptive solutions. The company aims to fill critical gaps in women's health by developing research-driven products that prioritize patient safety, efficacy, and accessibility. Their flagship products include 3D-001, a frameless, nonhormonal intrauterine device (IUD) designed to reduce insertion pain, and the Slider™ System, which features the i-Slider™ for insertion and the r-Slider™, a magnetic retriever for easy placement and removal. This technology leverages physics and geometry to improve comfort and minimize complications associated with traditional IUDs. 3Daughters targets women seeking reliable, long-acting contraception, particularly those who may be deterred by pain or hormonal side effects. The company has secured over $2 million in seed funding to advance its products through clinical trials, with a commitment to regulatory compliance and quality management. Their mission is to transform women’s healthcare by improving contraceptive accessibility and comfort.

Abiomed

Abiomed

Danvers, Massachusetts, United States

Based in Danvers, Massachusetts, USA, Abiomed, Inc., part of Johnson & Johnson MedTech, is a leading provider of medical technology that provides circulatory support and oxygenation. Our products are designed to enable the heart to rest and recover by improving blood flow and/or provide sufficient oxygenation to those in respiratory failure. For additional information, please visit www.abiomed.com. Important Safety Info: https://bit.ly/39kvb47

Access Vascular

Access Vascular

Billerica, Massachusetts, United States

Access Vascular is offering our suite of vascular access solutions designed to help clinicians address common catheter complications that afflict patients while helping save hospitals time and money.

Ace Vision Group

Ace Vision Group

Boston, Massachusetts, United States

Ace Vision Group, Inc. (AVG) is a privately held U.S. ophthalmic medical device company developing Laser Microporation Therapeutic technologies to address age-related eye dysfunction and address the eye's natural biomechanical performance. AVG's Laser Scleral Microporation (LSM) is a therapeutic eye laser treatment that aims to restore visual function naturally without sacrificing distance vision. AVG's brand promise is to provide the field of ophthalmology with innovative devices, Microporation Therapeutic procedures, and education for the treatment of age-related ocular dysfunction, disability, and disease.

Actipulse Neuroscience®

Actipulse Neuroscience®

210 Broadway, Cambridge, Massachusetts 02139, US

Actipulse Neuroscience® is a neurotechnology company focused on non-invasive brain stimulation therapies for neurological and psychiatric disorders. Founded in 2017, the company has offices in Cambridge, MA, and Paris, with a presence in Mexico. Actipulse aims to make neuromodulation treatments accessible by transitioning them from hospitals to home-based solutions, targeting conditions such as depression, Alzheimer’s, and Parkinson’s diseases. The company has developed a proprietary portable transcranial magnetic stimulation (TMS) device designed for home use. This device delivers high-frequency magnetic pulses to address issues like neuroinflammation and neuroplasticity loss. Actipulse is conducting clinical trials for major depressive disorder and exploring applications for neurodegenerative disorders. Their home-based treatment model allows for remote administration of TMS under clinical guidance, integrating with telemedicine platforms. Actipulse envisions establishing neuromodulation as a standard therapy alongside traditional pharmacological treatments.

Admetsys

Admetsys

21 dry dock avenue, boston, massachusetts, united states, 02210

Admetsys is a biomedical technology company specializing in critical care automation. The company's flagship PrecisionOne system is the first fully automated glycemic control system and continuous blood diagnostics platform for hospital care. The company was founded to commercialize the next generation of medical automation technology: continuous real-time biosensing, robotics, artificial intelligence and learning algorithms, intelligent therapeutic delivery, and advanced data telemetry.

Advanced Radiation Therapy

Advanced Radiation Therapy

1 Industrial Way, Unit 6, Tyngsboro, MA 01879, US

Advanced Radiation Therapy is the provider of AccuBoost. AccuBoost is the latest innovation in breast radiation therapy. The primary beneficiaries of the AccuBoost Technique are the breast cancer patients: who receive conformal radiation with better targeting, less toxicity, much less skin reaction, minimum exposure to the heart and lungs and a superior cosmetic result.

Alcresta Pharmaceuticals

Alcresta Pharmaceuticals

Newton, Massachusetts, United States

Alcresta Therapeutics is dedicated to developing and commercializing novel, enzyme-based products designed to address challenges faced by people living with gastrointestinal disorders and rare diseases. The company uses its proprietary technology platform to support a broad pipeline of products, with an initial focus on pancreatic insufficiency or fat malabsorption, which results in malabsorption common in cystic fibrosis, digestive cancers, preterm birth, and other serious diseases. The company’s lead product, RELiZORB®, is designed to reliably and efficiently deliver the optimal nutritional and caloric benefit from existing enteral feeding formulas by improving the breakdown and absorption of fats, in particular long-chain polyunsaturated fatty acids like omega-3 (including DHA, EPA). RELiZORB is indicated for use in pediatric patients (ages 5 years and above) and adult patients to hydrolyze fats in enteral formula. The company’s platform is supported by our extensive experience in pharmaceutical, medical device and nutritional product development. Based in Massachusetts, the company is backed by top-tier venture investors Athyrium Capital Management, Bessemer Venture Partners, Frazier Healthcare, and Third Rock Ventures.

Amplitude Vascular Systems

Amplitude Vascular Systems

451 D St, Boston, Massachusetts 02210, US

AVS is an early-stage medical device company focused on safely and effectively treating severely calcified arterial disease. It was founded in 2018 by Hitinder Gurm, M.D., Interventional Cardiologist and Chief Clinical Officer at University of Michigan, and Robert Chisena, Ph.D., Chief Technical Officer at AVS. We are redefining interventional therapy for severely calcified lesions with our Pulse IVL System, which uses a novel pulsatile mechanism of action to shatter calcium and expand narrowed vessels, all with a single device. To learn more about pulsatile intravascular lithotripsy, visit www.avspulse.com.

Axoft

Axoft

Cambridge, Massachusetts, United States

Developing seamless neural interfaces.

Beeken Biomedical

Beeken Biomedical

100 Carlson Ave, Building 11 Suite 206, Newton Centre, Massachusetts 02459, US

Beeken Biomedical is an medical device company focused on the development, licensing and commercialization of wound care products. Beeken Biomedical introduces innovative and cost-effective technologies that rapidly stop bleeding and help protect wounds from infection. Beeken Biomedical is committed to improve solutions in wound care for healthcare professionals and consumers.

Bluejay Diagnostics

Bluejay Diagnostics

Acton, Massachusetts, United States

Bluejay Diagnostics, Inc. is a medical diagnostics company focused on improving patient outcomes using its Symphony System, a cost-effective, rapid, near-patient product for triage and monitoring of disease progression.

Boston Medical Products, Inc.

Boston Medical Products, Inc.

70 Chestnut St., Shrewsbury, MA 01545, US

We are part of bess group (www.bessgroup.com), a group of dynamic and developing companies, headed by our holding company bess AG (Berlin, Germany). It is our vision to provide life sciences products of high value yet cost-effective, enabling us to become market leaders in as many of our medical fields as possible. Though much has changed at Boston Medical Products over the past 39 years, one thing remains constant: our commitment to deliver the world's finest specialty surgical products - products that clinicians rely on and patients can trust. Founded in 1980 by three physicians - including world-renowned ENT surgeon William W. Montgomery, M.D. - as a way to make Dr. Montgomery's original innovations widely available, Boston Medical Products continues to be driven by his life-long commitment to superior patient care. Over the years since our beginning, we have expanded our line of products with innovations from some of the world's leading physicians, health care innovators, and opinion leaders. Boston Medical Products today develops, manufactures and sells many different types of specialty products that meet the exacting needs of clinicians specializing in Otolaryngology, Pulmonary Medicine, Respiratory Therapy and Speech Pathology. In the established patient oriented tradition, Boston Medical Products has developed an educational website www.trachs.com as a service to provide patients with the very best products and resources for their laryngectomy and tracheostomy needs. It is a website where you can not only find the products you need for your care and comfort, but information and support that will help you make decisions and improve your quality of life.

Boston Scientific

Boston Scientific

Marlborough, Massachusetts, United States

Boston Scientific transforms lives through innovative medical technologies that improve the health of patients around the world. As a global medical technology leader for more than 40 years, we advance science for life by providing a broad range of high-performance solutions that address unmet patient needs and reduce the cost of health care. Our portfolio of devices and therapies helps physicians diagnose and treat complex cardiovascular, respiratory, digestive, oncological, neurological and urological diseases and conditions.

BrainsWay

BrainsWay

Burlington, Massachusetts, United States

BrainsWay is a global leader in advanced noninvasive neurostimulation treatments for mental health disorders. The Company is boldly advancing neuroscience with its proprietary Deep Transcranial Magnetic Stimulation (Deep TMS™) platform technology to improve health and transform lives. BrainsWay is the first and only TMS company to obtain three FDA-cleared indications backed by pivotal studies demonstrating clinically proven efficacy. Current indications include major depressive disorder (including reduction of anxiety symptoms, commonly referred to as anxious depression), obsessive-compulsive disorder, and smoking addiction. The Company is dedicated to leading through superior science and building on its unparalleled body of clinical evidence. Additional clinical trials of Deep TMS in various psychiatric, neurological, and addiction disorders are underway. Founded in 2003, with offices in Burlington, MA and Jerusalem, Israel, BrainsWay is committed to increasing global awareness of and broad access to Deep TMS.

Braintree Labs

Braintree Labs

Braintree, Massachusetts, United States

Sebela Pharmaceuticals is a U.S. pharmaceutical company with a market-leading position in Gastroenterology and a focus on innovation in Women's Health. Our Vision is to build the leading Gastroenterology company in the U.S., with a complementary focus on innovation in Women's Health, premised on our expertise in pharmaceutical development and commercialization. We value dedication, energy, and enthusiasm, and we focus on innovation and results while striving to achieve our corporate mission and vision. Sebela Pharmaceuticals is committed to cultivating an inclusive environment where all employees are treated with respect. We accomplish this by fostering a culture of diversity, equity and inclusion, which is essential to innovation and continuous improvement. Sebela operates from three locations with offices in Roswell, Georgia, Braintree, MA and headquarters in Dublin, Ireland.

Brixton Biosciences

Brixton Biosciences

1000 Massachusetts Avenue, Suite 101, Cambridge, MA 02138

Brixton Biosciences is a clinical-stage life sciences company developing novel therapies for chronic and acute pain. Their Neural Ice™ has the potential for long-lasting pain control from one injection, intended to eradicate the pain of pain.

CardioFocus

CardioFocus

500 Nickerson Rd, Marlborough, MA 01752, US

CardioFocus is a medical device innovator and manufacturer dedicated to advancing ablation treatment for cardiac disorders such as atrial fibrillation (AFib), the most common heart arrhythmia. The company's FDA-approved HeartLight Endoscopic Ablation System has successfully treated more than 10,000 patients in the United States, Europe and Japan. The HeartLight System is a revolutionary catheter ablation technology that along with direct visualization and titratable laser energy, represents a new standard for AFib ablation. CardioFocus is headquartered in Marlborough, MA. For more information, visit www.CardioFocus.com. Social Media Community Guidelines: bit.ly/2IDIBZR

Cogent Biosciences Inc

Cogent Biosciences Inc

Waltham, Massachusetts, United States of America

Cogent Biosciences, Inc., a biotechnology company, focuses on developing precision therapies to treat genetically defined diseases. Its lead product candidate includes CGT9486, a selective tyrosine kinase inhibitor designed to inhibit the KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. Cogent Biosciences, Inc. has a licensing agreement with Plexxikon Inc. for the research, development, and commercialization of CGT9486 and CGT0206 inhibitors. The company was formerly known as Unum Therapeutics Inc. and changed its name to Cogent Biosciences, Inc. in October 2020. Cogent Biosciences, Inc. was founded in 2014 and is headquartered in Cambridge, Massachusetts.

Cognito Therapeutics

Cognito Therapeutics

1218 Massachusetts Ave Ste 200

Cognito Therapeutics is a pioneer in non-invasive neuromodulation to treat neurodegenerative diseases and improve human cognitive performance. The company has completed multiple clinical studies demonstrating its investigational therapeutic has the potential to safely slow or stop cognitive decline and loss of brain volume in Alzheimer’s disease. Cognito has received FDA Breakthrough Device Designation for the treatment of Alzheimer’s disease and expects to start pivotal studies in 2022. The company’s technology was based on pioneering optogenetics research by scientific co-founders Professors Li-Huei Tsai and Ed Boyden at MIT.

Cognoptix_

Cognoptix_

Concord, Massachusetts, United States

Cognoptix is pioneering a new way to see Alzheimer's disease (AD): a low-cost, practical and non-invasive eye scan that detects beta-amyloid deposits in the lens. Amyloid is the earliest biomarker of AD, and our system can detect it years or decades before amyloid appears in the brain.

Corvia Medical

Corvia Medical

Tewksbury, Massachusetts, United States

Corvia Medical, Inc. is revolutionizing the treatment of heart failure with a novel transcatheter structural heart device. Founded in 2009 and headquartered in Tewksbury, MA, Corvia Medical is dedicated to transforming the standard of care for heart failure treatment, enabling patients to reclaim their lives. The Corvia® Atrial Shunt is the world’s first transcatheter device approved by the European Union to treat heart failure with preserved (HFpEF) or mid-range (HFmrEF) ejection fraction. Privately held, the company is backed by Third Rock Ventures, General Catalyst Partners, AccelMed, and Lumira Ventures, Edward Lifesciences and an undisclosed strategic investor. In the United States, the Corvia Atrial Shunt System is an investigational device and not available for commercial distribution or sale.

Cynosure

Cynosure

Westford, Massachusetts, United States

Cynosure is a leader in the medical devices industry specializing in aesthetic medicine and cosmetic procedures.

Cytrellis Biosystems, Inc.

Cytrellis Biosystems, Inc.

34 Commerce Way, Woburn, Massachusetts 01801, US

Cytrellis Biosystems, Inc. is a medical technology company located in Woburn, Massachusetts, founded in 2012. The company focuses on developing and commercializing innovative aesthetic devices aimed at dermatology and scar reduction. Its mission is to provide non-surgical solutions for sagging skin associated with aging, enhancing skin appearance and restoring youthful beauty. The primary product offered by Cytrellis is the ellacor System, which employs Micro-Coring Technology. This system is designed to treat moderate to severe wrinkles in adults aged 22 and older, specifically targeting the mid to lower face. The ellacor System enables aesthetic practitioners to effectively address age-related skin changes. Cytrellis Biosystems collaborates with leading physicians and partners to implement its aesthetic solutions. With a strong leadership team experienced in medical device development, the company is well-positioned in the beauty and personal care industry, competing with other notable players in the aesthetic and medical device sectors.

Diagnosys LLC

Diagnosys LLC

55 Technology Drive Suite 100, Lowell, Massachusetts, USA, 01851

We manufacture Vision electrophysiology testing equipment for detecting eye diseases and sold mainly to hospital and eye doctors. Based in the USA, we create the leading solutions for electrophysiology for all your needs in hospitals, research and drug trials

Dynocardia, Inc.

Dynocardia, Inc.

One Broadway, Cambridge, MA 02142, US

Dynocardia is a biomedical device development company committed to satisfying critical unmet needs to improve healthcare worldwide. ViTrack™, our lead diagnostic device, is powered our proprietary technology making it the only stand-alone, cuff-less device that allows for continuous, non-invasive blood pressure (cNIBP) measurement. Unlike conventional occlusive devices, ViTrack offers direct, beat-to-beat measurement of blood pressure that is wrist-wearable, mobile, and easy to use, with the accuracy of intra-arterial lines. ViTrack, with data-rich capability that includes heart rate, heart rhythm, and respiratory parameters in addition to blood pressure, enables early intervention prior to acute events.

Echosens

Echosens

Waltham, Massachusetts, United States

Echosens is a healthcare technology company that specializes in non-invasive diagnostic tools for assessing liver health.

Empatica

Empatica

45 Bromfield St, 901, Boston, Massachusetts 02108, US

Empatica is an affective computing company, focused on human data analytics. We develop groundbreaking wearable devices with medical quality sensing. Our technology comprises a set of wristband, software running on smartphone and desktop computing, plus real time syncing with a cloud computing service.

EnClear Therapies

EnClear Therapies

65 Park St, 3, Newburyport, Massachusetts 01950, US

At EnClear Therapies, we are combining Bioscience & Med-tech expertise to develop solutions that improve and extend the lives of patients with CNS disease. The team at EnClear is developing systems and medical interventions that Access, Recirculate & Modify CSF for: › Targeted removal of toxicity from CSF correlated to neurodegenerative disease progression. › Continuous localized delivery of therapeutics & monitoring of CSF to ensure effective and personalized therapy.

Encora Therapeutics

Encora Therapeutics

1 broadway, boston, massachusetts, united states

Encora Therapeutics is a healthcare technology company based in Boston, Massachusetts, founded in 2018. The company focuses on developing innovative, non-invasive wearable solutions for individuals with neurological movement disorders. Their mission is to enhance the quality of life for those affected by these conditions through advanced wearable technology and personalized treatments. The company specializes in wrist-worn vibratory stimulation devices that utilize artificial intelligence-powered vibration therapy. These wearables are designed to provide tremor relief and monitor disease progression, particularly for conditions like essential tremor. Clinical trials have shown significant reductions in tremor severity with their devices, which are user-friendly and well-tolerated. Encora Therapeutics employs advanced technologies such as signal processing and reinforcement learning to create effective solutions tailored to individual patient needs. Their clinical research has received recognition, including an "Abstract of Distinction" at the 2025 American Academy of Neurology Annual Meeting, underscoring the safety and efficacy of their products.

Epicore Biosystems

Epicore Biosystems

Cambridge, Massachusetts, United States

Epicore Biosystems is a digital health company developing advanced sweat-sensing wearables that provide real-time personalized health insights for hydration, stress, and wellness. Our clinically validated products are deployed globally and licensed by leading brands in the sports and fitness, occupational safety, and clinical trials industries.

Exergen

Exergen

Watertown, Massachusetts, United States

Exergen Corporation is the recognized world leader in industrial and medical non-invasive temperature technology. From providing temperature sensors for NASA and various industries to creating one of the world's most popular baby gifts, Exergen creates non-invasive temperature measurement devices providing lower cost, higher accuracy, less invasiveness, and greater reliability than ever previously possible. The creator of the first temporal artery thermometer—the Temporal Scanner™, the most efficacious, non-invasive thermometer ever created. Exergen holds over 100 U.S. and foreign patents, and is the only manufacturer of retail medical thermometers in the U.S. Presently, 30% of hospitals and pediatricians currently use the Exergen Temporal Scanner, and well over 1 million consumers use one at home. Founded by Harvard-research scientist Dr. Francesco Pompei over two decades ago, Exergen Corporation is based in Watertown, Massachusetts, USA.

Fractyl Health

Fractyl Health

Lexington, Massachusetts, United States

Fractyl Health is a leader in creating innovative therapies to address the root cause of type 2 diabetes. We were founded based on groundbreaking research and biological insights showing the key role of the intestine in metabolic control. Our therapies are uniquely designed to target and control this controller for the treatment of metabolic disease. Our lead program, Revita DMR, is a first-in-class procedural therapy that is now in late-stage clinical trials for the treatment of type 2 diabetes. Our team is made up of passionate innovators at the intersection of biology and technology, working to deliver better real-world outcomes for people with metabolic disease.

Freudenberg Medical

Freudenberg Medical

40 Sam Fonzo Drive, Beverly, Massachusetts 01915, US

Freudenberg Medical is a global partner for the design, development and manufacture of medical devices, components, and minimally invasive product solutions. Our comprehensive technical capabilities range from the design and manufacture of minimally invasive, catheter, and handheld technology to the development and production of medical components utilizing advanced materials and processes. We are an industry leader in the manufacture of high precision silicone and thermoplastic components and tubing as well as metal hypotubes and coating technology. Freudenberg Medical is part of the Freudenberg Group, a global technology group. As an organization, we ensure that every project is supported by our unmatched range of global resources, financial stability, and the flexibility to optimize for business performance. www.FreudenbergMedical.com Explore the possibilities with Freudenberg Medical, please call 877-308-0558 or email info@freudenbergmedical.com

GI Windows

GI Windows

381 University Ave, Westwood, Massachusetts 02090, US

GI Windows Surgical is a clinical-stage company engineering less invasive solutions for surgeons and patients.

HEMEDEX INC.

HEMEDEX INC.

Cambridge, Massachusetts, United States

HEMEDEX INC. was founded in 2000 to commercialize a proprietary platform technology conceived at the Massachusetts Institute of Technology (MIT) to quantify tissue perfusion (i.e., blood flow at the capillary level). This technology addresses the need for real-time, prognostic data in complex medical and surgical procedures. These complex procedures often involve compromised vasculature, delayed ischemia, or other serious pathophysiology, resulting in high rates of morbidity, delayed recuperation, poor patient outcome and higher overall costs. HEMEDEX's patented technology can provide an early warning of impending tissue ischemia, help target appropriate therapies, and rapidly assess the effect of interventions on cerebral blood flow (CBF), thus providing clinicians with a powerful tool to enhance patient care. HEMEDEX is ISO 13485:2012 certified.

Hyalex Orthopaedics Inc.

Hyalex Orthopaedics Inc.

99 hayden avenue, lexington, massachusetts, united states

Hyalex Orthopaedics is a venture backed Boston-based medical device start-up focused on developing and commercializing new products that feature HYALEX® materials technology. Unlike other polymers, synthetic HYALEX material has the unique capability of maintaining low friction and low wear under the high loads encountered in human joints. Hyalex Orthopaedics' products are in the development stage and have not been approved for use in humans by any regulatory agency.

HydroCision Inc.

HydroCision Inc.

267 Boston Road, Suite 28, Billerica, MA 01862, US

HydroCision, Inc. is a privately held medical device company focused on the development and commercialization of its proprietary fluidjet technology for sports medicine and spine applications. The tissue differentiating technology delivers a hair-thin, high velocity, nonthermal stream of saline to cut and simultaneously aspirate tissue without external suction. Application specific devices are designed to remove diseased tissue without harming surrounding healthy tissue in a minimally invasive manner. HydroCision technology is in commercial use through license agreements or direct commercialization in the fields of wound care, urology, spine, and sports medicine.

InfoBionic

InfoBionic

Lowell, Massachusetts, United States

InfoBionic.Ai's MoMe® ARC system empowers physicians with control to transform the efficiency with which they manage cardiac arrhythmia detection and monitoring processes for their patients. Leveraging a comprehensive, Cloud-based remote patient monitoring platform – the first and only of its kind – we deliver on-demand, actionable monitoring data and analytics directly to the physicians themselves. The MoMe® Kardia 3-in-1 device streams continuous ECG, respiration, and motion data to the Cloud for analysis, and delivers automated reporting to an iPad and or a web-based portal where physicians can access and interact with the data they need, in the detail they want – anytime, anywhere.

InfraReDx

InfraReDx

Burlington, Massachusetts, United States

There are still broad swaths of uncharted territories concerning the role lipid core plaques play in heart disease. Now, you can achieve unparalleled insights with the Infraredx Dualpro IVUS+NIRS catheter and its accompanying Makoto Intravascular Imaging System, FDA-cleared to identify patients and plaques at an increased risk of MACE. For more information about the Makoto Imaging System or Dualpro IVUS+NIRS Catheter visit www.infraredx.com. Infraredx, a Nipro Company is now proud to offer the OKAY II Y-Connector to the US market. The number one selling Y-Connector in Japan is now available. Visit www.infraredx.com/technology/nipro-okay-ii/ to learn how you can reduce blood loss with the OKAY II Y-Connector.

InnovHeart

InnovHeart

Newton, Massachusetts, United States

InnovHeart, with locations in Milan, Italy, and Boston, Massachusetts, develops transcatheter mitral valve replacement (TMVR) systems to treat patients suffering from mitral valve disease. The company is currently in clinical trials testing its novel TMVR Saturn Prosthesis, designed to be consistent with the anatomy of the mitral valve. Saturn is a low-profile prosthetic designed for both Trans-apical and Trans-septal delivery. Our company mission is to bring patients a novel therapeutic system suitable to replace incompetent Mitral Valves based on a safe, effective, and easy-to-use transcatheter technology. InnovHeart is committed to pursuing this goal with the highest level of quality.

INVO Bioscience

INVO Bioscience

Medford, Massachusetts, United States

At INVO bioscience, we are democratizing fertility. Our mission is to help people realize the dream of parenthood by increasing worldwide access to an efficient, effective, and connected experience in reproductive treatment. We are the manufacturers of INVOcell. The first and only FDA cleared, CE marked medical device used in intravaginal culture (IVC). INVOcell holds the gametes within the woman’s body during fertilization and early embryo development. A safe, intimate way for women to be connected right from the very beginning. With INVOcell, Life Begins Within™. We are looking for partners to help us bring treatment where it’s needed. We offer full-service partnerships including resources, training, clinical and lab support. Contact us to learn how you can join the movement to make advanced fertility care within reach.

LeMaitre Vascular

LeMaitre Vascular

Burlington, Massachusetts, United States

LeMaitre is a provider of devices, implants and services for the treatment of peripheral vascular disease, a condition that affects more than 200 million people worldwide. The Company develops, manufactures and markets disposable and implantable vascular devices to address the needs of its core customer, the vascular surgeon. The Company's diversified product portfolio consists of brand name devices used in arteries and veins outside of the heart. The company is listed on NASDAQ.

Leuko

Leuko

8 St Marys St, Boston, Massachusetts 02215, US

Leuko is developing the first non-invasive white blood cell device. White blood cell assessment is a first-line indicator for various medically-relevant situations, ranging from chemotherapy management to the detection of life threatening infections worldwide. This test is currently invasive and not readily accessible - it requires patient travel, blood draws and laboratory infrastructure. Based on MIT research, Leuko is re-imagining the way to perform these tests without extracting blood and in a portable device.

Lifeward

Lifeward

Marlborough, Massachusetts, United States

The ReWalk® Personal Exoskeleton offers patients with spinal cord injuries (SCI) a new level of independence with life-changing robotics. Use the ReWalk Personal Exoskeleton as part of a home-based functional ambulation program to elevate the health and quality of life for individuals with spinal cord injury. It is the only personal exoskeleton designed to keep up with users on stairs and curbs, enabling them to experience the benefits of walking again wherever life takes them. Learn more about the ReWalk Personal Exoskeleton and all of the products within the Lifeward portfolio here: golifeward.com/products Our mission is to fundamentally change the Quality of Life for individuals with lower limb disability through the creation and development of market leading robotic technologies. We currently offer solutions for stroke rehabilitation and spinal cord injury

Magellan Diagnostics

Magellan Diagnostics

North Billerica, Massachusetts, United States

Magellan Diagnostics is a medical device company that provides point-of-care systems, clinical laboratory instruments, and analytical laboratory services focused on lead testing.

Micro-Leads Medical

Micro-Leads Medical

255 Elm Street , Somerville, MA 02144, US

Micro-Leads is a medical device technology company developing injectable and laparoscopic, surgery-free devices for precision neurostimulation. Micro-Leads closed-loop platform reads the body's physiological response to stimulation and writes an adaptive stimulation therapy.

Micron Solutions

Micron Solutions

Fitchburg, Massachusetts, United States

Whether it is partnering with clients to help with design for manufacturing on new programs or to support existing applications, Micron Products, Inc. is prepared to commit all resources necessary to find a solution. As a Full Service Supplier, each member of our manufacturing, product design, research and quality teams stand ready to work in collaboration with clients to meet any challenge. Micron Products, Inc. has been supplying the medical industry with world class quality medical components since 1978. Micron Products, Inc. is a wholly owned subsidiary of Micron Solutions Inc. (NYSE: MKT: MICR)

myBiometry

myBiometry

Boston, MA

myBiometry is a platform to remotely monitor and manage patients with chronic conditions using software and biomarker data generated from proprietary sensors. Our initial focus is asthma.

Myolex

Myolex

beacon st, brookline, massachusetts, united states

Myolex is disrupting how to measure muscle wasting (and treatment), caused by obesity drugs, aging, and sport injuries. Myolex® EIM is a patented device technology and SaaS data analytics platform that is built to disrupt skeletal muscle measurement by becoming the clinical and wellness standard to aid in the diagnosis and treatment of obesity drug and age-related muscle wasting. Myolex has developed the 1st quantitative, sensitive, painless, portable for home use muscle quality assessment device that is specifically designed to non-invasively, comprehensibly, and precisely detect and monitor single muscle wasting.

Myomo

Myomo

Cambridge, Massachusetts, United States

Myomo is a healthcare technology company that specializes in assistive technology for rehabilitation and mobility solutions.

Navigation Sciences

Navigation Sciences

clinton rd, brookline, massachusetts, united states, 02445

Navigation Sciences™ is a clinical-stage company developing the NaviSci™ System for the tissue conserving removal of lung cancer and other soft tissue tumors. The system integrates Augmented Reality (AR) and advanced software with surgical instruments to guide precise surgical resection by enabling for the first time, real-time in-vivo margin measurement. The system aims to improve surgical outcomes with cutting-edge technologies that – reduce recurrence risk and conserve lung function – shorten hospital length of stay and enhance surgical workflow.

NeuroBionics

NeuroBionics

444 Somerville Ave, Somerville, Massachusetts 02143, US

NeuroBionics is pioneering the future of precision bioelectronic medicine by developing the next generation of implantable devices, designed to seamlessly interface with the human body. Our core technology lies in flexible, multifunctional fibers the size of a human hair, which can record and stimulate neural activity, deliver drugs, and ablate tissue. Using an endovascular approach, we will navigate our microscopic-sized flexible fiber implant through the intricate network of blood vessels to deliver precise therapeutic intervention to neural tissue. By making neural interfacing a minimally-invasive procedure, we will revolutionize deep brain stimulation and broaden access to this lifechanging therapy. By doing so, we aim to improve the lives of millions grappling with conditions like Parkinson's disease, essential tremor, epilepsy, and depression.

Neutron Therapeutics LLC

Neutron Therapeutics LLC

1 Industrial Dr, Danvers, Massachusetts 01923, US

Neutron Therapeutics LLC is a pioneer in Boron Neutron Capture Therapy (BNCT) using our nuBeam platform, the world's only neutron beam for BNCT that conforms to IAEA international standard for clinical use.

Nova Biomedical

Nova Biomedical

Billerica, Massachusetts, United States

Nova Biomedical is a company dedicated to using advanced technology to develop better blood testing analyzers for medical use. These products are called in vitro diagnostic devices (IVD). We use some of the same advanced technology to provide the biotechnology industry with innovative instruments for cell culture monitoring. Nova is the largest privately owned IVD company in the U.S. and the third largest in the world, with over 1,200 employees globally. Our eight percent compounded annual growth over nearly a decade is more than double the IVD market growth, making Nova one the fastest growing IVD companies in the world. Corporate Commitment to Quality Nova's size and rapid growth are the result of customers throughout the world responding to the exceptional quality and value of Nova's technology, products, and customer service. Our strong corporate commitment to these three areas has made Nova a world leader in clinical, veterinary, and biotechnology chemistry testing analyzers. A Leader in Medical Science Technology Maintaining leadership in any technology industry requires a long-term perspective and commitment to research and development. Nova Biomedical has consistently invested more than 10 percent of sales into research and development — more than double the industry average. Our investment in research and development provides a continuous product pipeline of new and better technology products for our customers. Working at Nova Biomedical We practice our core values of mutual respect, honesty, and integrity throughout Nova. With a strong sense of family in the workplace, we are proud that one third of all our employees have been with us for over 10 years.

NxStage

NxStage

Lawrence, Massachusetts, United States

NxStage is more than just a company; we are leading the renal revolution. By our own design, we’re at the leading edge of a movement to transform renal care. To make it simpler. To make it portable. To expand treatment options for clinicians by overcoming traditional barriers. To enhance patient freedom and fulfillment. With significant breakthroughs already behind us - and others in the pipeline - NxStage is finding itself at the forefront of dramatically improved renal care, thanks to innovative yet simple therapeutic solutions that benefit patients, caregivers, and society. Our approach – and success is inspiring patients and providers.

Organogenesis

Organogenesis

Canton, Massachusetts, United States

Organogenesis™ is a leading regenerative medicine company focused on the development, manufacture, and commercialization of solutions for the advanced wound care and surgical and sports medicine markets. Organogenesis offers a comprehensive portfolio of innovative regenerative products to address patient needs across the continuum of care.

OSSIO

OSSIO

Woburn, Massachusetts, United States

Ossio is an orthopedic medical device company founded in Israel in 2014 with the vision to completely transform the orthopedic experience for physicians, patients, and payors. Ossio's mission is to replace metal implants as the standard of care in the $10B+ orthopedic fixation market (screws, pins, plates) with an intelligent bone regeneration technology. OSSIOfiber™ represents a breakthrough material platform for orthopedic and podiatric surgeons who seek a more biologically friendly way to restore mobility with nothing permanent left behind. Our products have the mechanical strength needed for easy insertion and secure fixation while enabling the body to regrow bone, completely incorporating and replacing the implant without the adverse inflammation and weakness often seen in “bio-resorbables”.

PathMaker Neurosystems

PathMaker Neurosystems

Boston, Massachusetts, United States

PathMaker Neurosystems is a near-commercial stage neuromodulation company founded to commercialize recent advances in the development of non-invasive devices for the treatment of patients with serious neurological conditions. The company's technology is based on the premise that electrical fields can be used to stimulate the nervous system in a non-invasive manner, offering the potential to treat a wide range of neurological disorders.

Podimetrics

Podimetrics

Somerville, Massachusetts, United States

Podimetrics is the creator of the SmartMat™ and integrated clinical and patient support services that can help save the limbs and lives of patients living with complex diabetes. We provide high-risk patients our SmartMat™ through partnerships with payers and at-risk providers, including the Veterans Health Administration. After placing their feet on the mat for just 20 seconds a day, patients’ data are automatically sent to our care management team, which helps address any concerning findings. By combining cutting-edge technology with best-in-class care management, Podimetrics earns high engagement rates from patients and allows clinicians to achieve unparalleled outcomes — keeping vulnerable patients healthy at home and saving limbs, lives, and money. Founded in 2011 by a physician and engineers from MIT and Harvard, Podimetrics is headquartered in Somerville, M.A., and backed by Norwich Ventures, Scientific Health Development, Polaris Partners, and Rock Health. For more information, go to www.podimetrics.com or follow us on Twitter @podimetrics.

Ras Labs

Ras Labs

Quincy, Massachusetts, United States

Collaborative robots have reshaped automation by enabling a wide spectrum of new applications in different industries – but a significant dexterity gap still remains even with these robots. Manipulation of delicate, fragile, or brittle items is still out of reach for robots. Inspired by our human fingertips which provide unmatched dexterity, we have set out to reduce this gap by adding tactile sensing similar to the sensing in our fingertips to enable robotic manipulation of more delicate items. Introducing the Tactile Fingertip. Ras labs has combined material science innovation with data science and precision engineering to provide the first state of the art, Tactile Fingertip for robotic gripper fingers. Our sensor is based on our patented Electroactive Polymer which can be fabricated in many configurations. Both squishy and a level of firmness. Think our revolutionary technology could help your business? Send us a message. We'd love to chat!

Reprieve Cardiovascular

Reprieve Cardiovascular

Milford, Massachusetts, United States

Reprieve Cardiovascular, Inc. is developing innovative and groundbreaking therapies that aim to improve the lives of more than 25 million heart failure patients around the world. Reprieve is bringing intelligence to decongestion management to safely accelerate fluid removal for heart failure patients. In 2022, Reprieve initiated the FASTR Trial (pilot study) to compare decongestive therapy administered by the Reprieve Decongestion Management System to Optimal Diuretic Therapy in the treatment of patients diagnosed with acute decompensated heart failure. Reprieve is a privately held medical device company, headquartered in Milford, Massachusetts, USA.

RevBio, Inc.

RevBio, Inc.

600 Suffolk Street, Suite 250, Lowell, MA 01854, US

RevBio was started with one goal in mind—to end medicine's 50 year search for a biocompatible bone adhesive. Effective for bone-to-bone as well as bone-to-metal wet field applications, Tetranite® is a revolutionary biomaterial that promises to transform bone repair—for both patients and clinicians. Inspired by the marine animal the sandcastle worm, Tetranite is simple chemistry. Bioengineered from the worm's secreted protein, our synthetic adhesive is the only patented biomaterial which satisfies both the required and desired properties for a bone adhesive: wet field performance, multi-surface bonding, rapid mechanical stability, and controlled biodegradability. The properties of Tetranite™ include the ability to provide immediate fixation of bone to bone and bone to metal. This adhesive has been shown in multiple animal studies to be a non-toxic and effective way of repairing bone fractures and defects as well as securing implant devices. Existing data has also shown that Tetranite™ is reabsorbed and replaced with new bone during the natural process of bone remodeling by acting as a scaffold to facilitate bone growth over time.

Rhinostics

Rhinostics

Boston, Massachusetts, United States

Rapid Reliable Results COVID testing has shined a light on a major bottleneck in the laboratory workflow for accessioning samples, decapping of the samples, and movement of the samples into high throughput assay workflows. Rhinostics offers a simple and elegant solution that can remove time and significant labor, allowing laboratories to move larger number of samples through their laboratories at a lower cost, lower error rates, and with time savings. Rhinostics is revolutionizing sample collection with comfortable, automatable, rapid solutions that concentrate samples that save time, costs, and improve assay sensitivity. The polypropylene anterior nares (nostril) collection device is comfortable and easy for self-collection or in the clinic. It is connected to a threaded cap that can be automatically decapped using the Hamilton Lab Elite instrument. The samples can be shipped dry (RT-PCR does not require live virus so viral transport media (VTM) is not required. The entire 96 well plate of vials can be simultaneously scanned through a 2D barcode on the bottom of the collection vial and the automated decapper robot can be connected to other liquid handling systems and linked into the high throughput assay workflow.

Riparian Pharmaceuticals

Riparian Pharmaceuticals

Cambridge, Massachusetts, United States

Riparian Pharmaceuticals is an early stage biotechnology company employing innovative models of vascular pathophysiology to discover novel therapeutics In nature, the riparian zone is a unique rich ecosystem created through the interaction of a river with its banks. In the human body, moving blood, or hemodynamics, similarly interacts with the walls of blood vessels generating unique biological activity. This very interaction, between hemodynamics and the vascular wall, is a critical and unexplored determinant of vascular health. Riparian is deploying hemodynamics as a tool to discover first in class therapeutics acting on new pathways at an earlier stage of disease than is possible today.

Signifier Medical Technologies Ltd

Signifier Medical Technologies Ltd

175 Highland Ave, Needham, Massachusetts 02494, US

Signifier Medical Technologies Ltd is a medical technology company based in London, UK, with a U.S. office in Needham, Massachusetts. Founded in 2015, the company specializes in non-invasive solutions for sleep-disordered breathing conditions, particularly snoring and sleep apnea. Its mission is to enhance population health and lower healthcare costs through innovative therapies that focus on daytime treatments, avoiding surgical implants or wearable devices during sleep. The flagship product, eXciteOSA®, is an FDA-cleared device designed for mild obstructive sleep apnea and snoring. It employs neuromuscular electrical stimulation to strengthen tongue muscles, helping to reduce airway collapse during sleep. Signifier Medical Technologies is committed to retraining upper airway muscles as an alternative to traditional CPAP machines and surgical options. The company has established partnerships, including a significant order from Spectrum Sleep Solutions Inc., reflecting its growing presence in clinical channels and sleep therapy providers.

Smith & Nephew

Smith & Nephew

Andover, Massachusetts, United States

Smith & Nephew plc is a healthcare company that specializes in medical devices for orthopedics, wound care, and surgical equipment.

Solid Biosciences

Solid Biosciences

Boston, Massachusetts, United States

Solid Biosciences (Solid) is a life science company singularly focused on solving Duchenne muscular dystrophy (Duchenne). We aim to be the center of excellence across the entire disease spectrum, serving as a catalyst to bring together those with the expertise in science, technology, disease management and care. Disease-focused and founded by a family directly impacted, our mandate is simple yet comprehensive - attack the roots of the disease and improve daily life for patients.

SpectraWAVE, Inc.

SpectraWAVE, Inc.

12 Oak Park Dr, Bedford, MA 01730, US

SpectraWAVE, located in Bedford, Mass., is a privately held medical device company founded in 2017 to provide unrivaled optical and computational insights to improve the treatment and outcomes for patients with coronary artery disease (CAD). CAD, the buildup of plaque in the wall of the arteries that supply blood to the heart, affects 18.2 million adults age 20 and older. In CAD patients that undergo percutaneous stent placement, it is estimated that one in five patients experience adverse events within two years. SpectraWAVE’s state of the art HyperVue™ Imaging System combines next generation DeepOCT™ images and near infrared spectroscopy (NIRS) with workflows optimized for the cardiac catheterization lab. The HyperVue Imaging System is intended for the imaging of coronary arteries and is indicated in patients who are candidates for transluminal interventional procedures. The NIRS capability of the system is intended for the identification of patients and plaques at increased risk of major adverse cardiac events. For more information and complete indications for use, please visit www.spectrawave.com.

Theromics

Theromics

West Bridgewater, Massachusetts

Theromics has developed a novel, safe Thermal Accelerant used during the microwave, RFA, or cryoablation procedures of soft tissue, fibroids, and bone HeatSYNC can augment the reach of thermal energy from a distance normally unattainable by microwave or radiofrequency devices, thus high-power energy is not needed. The gel is also being studied for use as a drug delivery system combined with thermal ablation for a new therapy called TACT - Thermally Activated Combination Therapy.