List of Medical Device Companies in Belgium - 5

ElmediX is an oncology company committed to develop innovative medical technologies that can boost conventional anticancer therapies through Hyperthermal Therapy. Our main goal is to increase patient quality of life and survival. Our HyperTherm platform is a semi-automated, real-time system which offers accurate, highly-reliable and sensitive temperature control of the patient during treatment. A software-based technology is responsible for an accurate thermal mapping of the patient’s body; this guarantees that the temperature remains within a safe range during treatment. We have an ongoing clinical trial investigating the safety of thermal therapy in advanced solid cancer patients. The trial focuses on patients who do not respond to current standard therapies, patients with cancer types not adequately addressed by available therapies or patients that refuse standard of care treatment. For more information about the clinical trial, please use the following link: https://clinicaltrials.gov/ct2/show/NCT04467593?cond=Pancreatic+Cancer&cntry=BE&draw=2&rank=5 For more information about ElmediX, please check our website: www.elmedix.com

Gabi SmartCare offers an all-in-one system for home-based pediatric care, tailored to your organization's needs. Our platform simplifies screening, diagnosis, and management of pediatric conditions, supporting healthcare providers in delivering optimal care and providing peace of mind to parents.

Miracor Medical SA is a European medical device company dedicated to improve clinical outcome of patients with impaired cardiac function. Miracor develops and studies the PiCSO® (Pressure-controlled intermittent Coronary Sinus Occlusion) Impulse System, which is used as an adjunctive technique during the primary PCI procedure for acute myocardial infarction patients. PiCSO therapy seeks to improve coronary microvascular function to reduce infarct size and salvage myocardium, thereby improving outcomes of ST-elevation myocardial infarction (STEMI) patients. Recent Clinical Studies have successfully demonstrated the safety and positive effects of PiCSO on coronary microvascular function and infarct size reduction in STEMi patients. The company is conducting further clinical trials in Europe and plans to initiate a US IDE randomized controlled trial in 2023. Miracor has won several innovation awards and completed financing rounds raising venture capital and public funding. The company was founded in May 2008 by Professor Dr. Dr. Werner Mohl and the European venture capital firms Earlybird and Delta Partners.

Nyxoah is a pioneering medical device company developing a breakthrough therapeutic solution for the treatment of Obstructive Sleep Apnea (OSA). Our mission is to become a world leading company by offering unique patient-centric neuromodulation solutions, developed by passionate and exceptionally driven people Nyxoah's therapy Genio® offers: - Unparalleled clinical efficacy - Increased patient comfort, therapy compliance and quality of life - Minimally invasive approach, thus streamlining patient flow and reducing surgery related risks - Positive health economics outcomes by reducing the burden of OSA and its comorbidities

Sequana Medical NV is a pioneer in treating drug-resistant fluid overload, a serious and frequent clinical complication in patients with liver disease, heart failure and cancer. Fluid overload is a well-recognized problem in these growing diseases, causing severe problems for the large number of patients for whom current medicines are no longer effective. These patients can have up to 15 liters of extra fluid in their bodies, causing major medical issues including increased mortality, repeated hospitalizations, severe pain, difficult breathing and restricted mobility that severely impacts daily life. alfapump® and DSR® are Sequana Medical's proprietary approaches that work with the body to remove this excess fluid, delivering major clinical and quality of life benefits for patients and reducing costs for healthcare systems. Sequana Medical is listed on Euronext Brussels (Ticker: SEQUA.BR) and headquartered in Ghent, Belgium. For further information, please visit www.sequanamedical.com.