List of Lentiviral Vector (LVV) Companies in Canada - 5

Biocure Technology Inc. is a biopharmaceutical company comprised of leading scientists specializing in the development and commercialization of its own CAR T-cell therapy, targeting Chronic lymphocytic leukemia and solid tumor cancers. Additionally, the Company is developing Biosimilar technologies for cancer treatment. The CAR T-cell cancer therapy space is one of the most innovative cancer treatments currently in the market and is seeing huge global interest. Founders and management are driven by a social agenda aimed at providing a global answer to highly priced biological medicines that remain outside the reach of common people. The company has unique scientific and execution skills to address the high barriers of CAR-T cell therapy and Biosimilar technologies, therefore is well positioned to gain leadership in the rapidly growing market of CAR T-cell cancer therapy.

Our team at BriSTAR Immunotech is dedicated to the development and commercialization of innovative T cell immunotherapy products for the treatment of cancer and viral infections with urgent unmet medical needs. We leverage our proprietary STAR-T platform to engineer next-generation T cell therapies for treating hematological malignancies and solid tumors. The STAR-T platform combines the advantages of CAR-T (Chimeric Antigen Receptor T-Cell immunotherapy) and TCR-T (T Cell Receptor T-cell immunotherapy) to produce mono- or bi-specific T cell therapies. The promising antitumor actions of STAR-T cell therapies include better antigen sensitivity and stronger tumor infiltration. These properties are critical for achieving better responses in cancer patients, especially in treating solid tumors.

Saguaro develops non-toxic fluorescent dyes that offer new insights into biological systems, empowering researchers to advance their understanding of disease and improve decision-making in drug development. We are a strong team on a mission to develop truly innovative products that can generate step-function improvements to life science research, and ultimately help people live longer and healthier. Saguaro's non-toxic dyes are mix-and-read and comprise: - ChromaLIVE. A data-rich dye capturing a wide range of biology for live-cell painting - NucleoLIVE: Biologically inert nuclear dye that finally simplifies segmentation in live cells, and is perfect to generate growth curves and quantify cell toxicity. - LIVE/Dead Stain: Offering fast and sensitive quantification of both live and dead cells, and deeper insights on cytoxicity with real-time data.

Sernova (TSX: SVA) (OTCQB: SEOVF) is a clinical-stage biotechnology company that is advancing a novel cell therapy platform for the treatment of chronic diseases. Our lead program is evaluating our Cell Pouch System™ as a potential ‘functional cure’ for insulin-dependent diabetes. In addition, we have a robust pipeline that includes preclinical programs in hemophilia A and hypothyroidism.