List of Gene Editing/CRISPR Companies in Missouri - 6

Agragene has developed Precision-Guided Sterile Insect Technology that will reduce grower's reliance on the 6 billion pounds of pesticides used on crops each year. Agragene is ready to deploy its first "Knock-Out" product in the field which targets spotted wing drosophila. The "Knock-Out" product will benefit crop growers in 3 key ways. 1) The product is much cheaper than the chemical pesticides used now, 2) scarce and expensive field labor is not required and 3) the resulting pesticide-free crop can be Organic-approved which increases grower's profits. Importantly, "Knock-Out" is non-toxic to bees, other beneficial organisms, the environment and humans. With many states and countries banning pesticides growers must look to safer and cheaper alternatives. Agragene has the solution.

Canopy Biosciences, a Bruker company, empowers innovation by providing access to cutting-edge spatial biology and multi-omic tools so biomedical researchers can drive scientific discovery faster. Our proprietary technology ChipCytometry™ is a quantitative multiplex immunofluorescence imaging method for the spatial analysis of complex tissues and mapping of cell populations with single-cell resolution. Supported by Canopy Spatial Services™ with our CLIA-certified laboratory, we provide a unique collection of spatial and single-cell technologies that accelerate the understanding of cellular diversity and interaction. Learn more at CanopyBiosciences.com.

Elemental Enzymes Ag and Turf, is a life sciences company that discovers, develops and produces innovative products to increase crop yields. Elemental Enzymes was founded in 2011 on technology to make and stabilize novel enzymes and has grown to address the agriculture market with enzyme and chemical technologies that have an "outside in" approach to address crop needs. Elemental Enzymes is delivering world class products to top agricultural companies through license and sales opportunities. Elemental Enzymes is always looking for energetic, challenge driven staff to continue support of current products and lead its' innovative pipeline to market.

Plastomics' novel trait delivery technology harnesses the power of the plant cell to create crops than can better withstand the pressure of insects, diseases and weeds and that are more efficient and deliver higher yields. Plastomics technology will give seed companies the benefits of simplified product development, more effective products and new market opportunities.

Many solutions to global threats such as climate change, disease and crop infestation can be found right beneath our feet. Microbes in the soil have proven potential to sequester carbon, improve crops, kill pests, reduce disease and more. Pluton Biosciences utilizes unique Micromining™ technology to discover novel microbes and create innovative solutions to address key sustainability challenges facing agriculture.

Wugen is a clinical-stage biotechnology company developing the next generation of off-the-shelf memory natural killer (NK) and CAR-T cell therapies for cancer. Wugen is leveraging its proprietary Moneta platform and deep genomic engineering expertise to pioneer a new class of memory NK cell therapies to treat hematological and solid tumor malignancies. Wugen is based out of St. Louis, Missouri and San Diego, California.