List of Devices Companies in Minnesota - 36

4C Medical Technologies, Inc. is a medical device company developing a novel minimally invasive solution for the treatment of mitral regurgitation (MR). We are the first transcatheter MR therapy that directly addresses mitral regurgitation without replacing the native mitral valve, thus preserving the native mitral annulus and left ventricle. The device is positioned supra annular to the leaking native mitral valve to stop the leak from entering the left atrium. Its atrial only fixation ensures minimal disruption to critical cardiac structures within the left ventricle including the chordae tendineae and the left ventricular outflow tract. Our initial focus is to develop a novel therapy for mitral regurgitation (MR), and subsequently for tricuspid regurgitation (TR).

Alpheus Medical, Inc, is a privately held company based in Oakdale, Minnesota, developing a novel sonodynamic therapy platform targeting solid body cancers. The company's lead product utilizes a novel, non-invasive drug device combination for outpatient treatment of recurrent glioblastoma multiforme (rGBM). Alpheus Medical's work has been developed in conjunction with some of the most accomplished names worldwide in neuro-oncology, and with support from the American Cancer Society and National Brain Tumor Society.

Birchwood is a healthcare company that offers incontinence and wound care products to healthcare professionals and patients.

Courante Oncology is a full-service clinical research provider specializing in oncology product development. We offer a wide range of clinical trial management and support services to the pharmaceutical and medical device industries, including project management, clinical site monitoring, quality assurance, and medical writing servies. We believe the challenges of oncology clinical trials require a research team that is uniquely experienced and trained. Our strength lies in our collective experience and our ability to adapt to and meet our clients' specific research needs.

Cryosa is a clinical stage company developing a treatment for moderate to severe Obstructive Sleep Apnea (OSA). We believe that mask-free, hose-free, implant-free treatment is possible. Everyone is free to sleep, free to rest and free to live brighter days.

CVRx is a commercial stage, public (NASDAQ: CVRX) medical devices company located in Minneapolis, Minnesota. The company has developed proprietary implantable technology for the treatment of high blood pressure and heart failure. Barostim™ triggers carotid baroreceptors - the body's own natural blood flow regulation system - which signals the brain to regulate cardiovascular function. Patient Stories on CVRx: The accounts and quotes of patients are genuine and documented. These stories represent a unique individual experience and does not provide any indication, guide, warranty or guarantee as to the response other people may have to CVRx technologies. Barostim is a prescriptive device. For a list of all potential benefits and risks go to www.cvrx.com/benefit-risk-analysis/

Endogenex, in partnership with Mayo Clinic, aims to revolutionize treatment options for individuals with type 2 diabetes (T2D). Endogenex's innovations focus on resetting the body's metabolic signaling system by harnessing its natural regenerative capabilities to improve metabolic function. Through the development of the ReCET System and the novel application of precise, controlled, non-thermal pulsed electric fields, Endogenex is establishing a new era in treatment options for people living with T2D, helping patients regain control of their blood glucose levels and slow disease progression. Endogenex is a privately held, clinical-stage company based in Minneapolis, MN.

Envoy Medical (Nasdaq: COCH) is a hearing health company focused on providing innovative technologies across the hearing loss spectrum. Envoy Medical has pioneered one-of-a-kind, fully implanted devices for hearing loss, including its fully implanted Esteem® active middle ear implant, commercially available in the U.S. since 2010, and the fully implanted Acclaim® cochlear implant, an investigational device. Envoy Medical is dedicated to pushing hearing technology beyond the status quo to improve access, usability, compliance, and ultimately quality of life.

FastWave Medical is developing novel, cost-effective intravascular lithotripsy systems for calcific artery disease. Learn more here.

Overactive bladder (OAB) affects over 15 million women in the US. The sudden, urgent desire to pass urine greatly limits quality of life. Current treatments are not optimal, requiring frequent, time-consuming office visits, awkward vaginal probes, medications with potential side effects or surgery. Those suffering with OAB often consider the therapies too cumbersome and forgo treatment, opting instead to place limits on their life to accommodate the symptoms. Neuromodulation for OAB involving electrical stimulation of the sacral nerve is a proven and established therapy. However, despite being commercially available for over a decade only a small fraction of indicated patients have been treated. The cost and invasiveness of the surgery are often cited as concerns by prospective recipients. FemPulse has developed a novel, wearable medical device designed to deliver neuromodulation therapy directly to the nerves that regulate bladder function, without the need for surgical implant. The small device is easily placed by the patient herself and controlled with a smartphone app. The company is currently conducting clinical evaluations in the United States.

For ordering information, please contact: 3M+KCI at +1-800-275-4524, KCI Express® https://mykci.com/kci-express, or Your local 3M+KCI Sales representative ________________________ Managing ostomy complications and intestinal fistulas is a challenge. A high output ostomy stoma or enteric fistula can produce two to seven liters of effluent per day which can cause edema, wound formation, complications and infections. To improve the management of patients with enteric fistulas and high output ostomy stomas we developed the Wound Crown®, Fistula Funnel® and Isolator Strip®. These barrier devices have been used effectively to compress the surface of the body around enterocutaneous fistulas, enteroatmospheric fistulas, ostomy stomas, and wound drains with moderate to high output levels to seal and protect the perimeter skin from effluent and reduce edema.

Francis Medical is developing minimally invasive treatment solutions for prostate, kidney, and bladder cancer through the use of convective thermal water vapor. Currently, the company is in clinical trials for ablating cancerous prostate tissue. Founded in 2018, Francis Medical is located in Maple Grove, Minnesota. Francis Medical, Inc., formerly named NxPhase Medical, Inc., is a company that was created after Boston Scientific (BSC) acquired NxThera, Inc. in April of 2018. As a part of the BSC/NxThera transaction, a separate and independent entity, NxPHASE Medical, Inc. (“NxPHASE”), was established, and shares of NxPHASE were distributed to the shareholders of BSC/NxThera. In addition, BSC/NxThera granted NxPHASE a license to utilize BSC/NxThera’s convective vapor ablation technology to develop, evaluate, and commercialize certain devices to treat prostate, kidney and bladder cancer (“NxPHASE Field of Use”), while BSC/NxThera remains focused on the treatment of benign prostatic hyperplasia. Late in 2018, NxPhase Medical, Inc. went through a rebranding process and selected Francis Medical, Inc. as its new brand and identity. The name and foundation of the company are a tribute to and legacy of Michael Hoey’s (founder/inventor) father, Francis Hoey, whose life was ended by prostate cancer with treatments that had harsh implications on his normal daily living.

Liberty Oxygen and Medical Equipment enables you to stay safe and independent in your home by offering a comprehensive array of home medical equipment & oxygen [including CPAP supplies, compression stockings, bath aids, canes, wheelchairs, walkers & more] in addition to prompt, personalized care. With 7 locations in the Twin Cities metro, there's always a store convenient for you. Burnsville 14001A Grand Ave S 952-898-5008 Coon Rapids 11650 Round Lake Blvd 763-231-2177 Maple Grove 16322 County Road 30 763-494-4966 Maplewood 1715-D Beam Avenue 651-789-7500 Saint Louis Park 4820 Park Glen Road 952-920-0460 Shakopee 1667 16th Ave E, Suite 102 952-445-5454 Woodbury 1815 Radio Drive 651-789-0050

Lifecore Biomedical is a full-service contract development and manufacturing organization (CDMO) that partners with pharmaceutical and biotech companies to develop and deliver vital and complex injectable therapies. We're also a manufacturer of premium sodium hyaluronate. From formulation to commercialization, we have everything it takes to move your project to the next level, making progress possible for our partners, people and most importantly, patients. Working from state-of-the-art facilities, our people are subject matter experts, our capabilities customized, our processes and systems qualified and our infrastructure optimized to meet your most sophisticated requirements regardless of scale. Our expertise is in drug products that are challenging and difficult to formulate, sterile filter, and aseptically fill. We've been the global leader in pharmaceutical-grade sodium hyaluronate (NaHy) for nearly 40 years. Leveraging this experience alongside deep expertise and capabilities in highly viscous solutions, we create tailored solutions that solve your drug development challenges across the entire development and manufacturing lifecycle. Our capabilities: Sterile Injectable Development - Formulation Development - Sterilization Development - Process Development - Analytical Services & Stability - Engineering Services - Validation Services Sterile Injectable Manufacturing - Sterilization - Aseptic Filling - Packaging - Analytical Services & Stability

Melodi Health offers novel technologies that improve patient outcomes for women undergoing breast surgery. Melodi Health manufactures the Melodi Matrix, designed to support the soft tissue space around a prosthetic device while delivering antibiotics to the surrounding tissue. The Melodi Matrix is currently an investigational device being studied in a prospective, multi-center, randomized, controlled clinical trial in breast reconstruction.

Mérieux NutriSciences Italia, appartenente all'Institut Mérieux, è impegnata a livello globale nella salvaguardia della salute dei consumatori e della sostenibilità, offrendo un'ampia gamma di test laboratoriali e servizi consulenziali nei settori alimentare, farmaceutico, packaging, cosmetico, ambientale. Leader di riferimento nel mercato italiano grazie ad una consolidata esperienza nei servizi analitici di chimica, microbiologia e biologia, Mérieux NutriSciences Italia adotta un approccio a 360° per fornire soluzioni pratiche e innovative ai suoi clienti mediante le attività di analisi, consulenza, audit, training, etichettatura e supporto normativo, ricerca, studi sensoriali e molto altro ancora. Giovane e dinamica, nonostante gli oltre 40 anni di storia, Mérieux NutriSciences Italia opera nel rispetto di elevati standard etici e di qualità e accoglie con favore l'opportunità di coinvolgere giovani talenti, che contribuiscono in modo significativo all'innovazione e alla crescita sostenibile dell'azienda. Visita la nostra pagina > www.merieuxnutrisciences.com/it/lavora-con-noi

Since 1996, Minnetronix Medical has accelerated medical device breakthroughs as a design, development and manufacturing partner to leading device companies around the world. Today, through life-cycle efficiency, opportunity realization, and increased utility, the organization is creating value in key technology segments, including RF energy, fluid and gas management, optical systems, and stimulation and active wearables. From design and manufacturing services to whole product solutions, Minnetronix brings expansive industry insight and intentional technical acumen, delivering better medical devices to market, faster. Minnetronix is based in St. Paul, Minnesota. ​

Morari's objective is to restore confidence in male sexual health by eliminating the embarrassment and frustration of premature ejaculation (PE). PE is the most prevalent male sexual dysfunction, estimated to affect 30% of men worldwide. With a higher incidence than erectile dysfunction or an enlarged prostate, men rarely talk about it or seek treatment. The Morari product concept would allow the male who desires a delay in ejaculation to use an external device that when activated by either partner, would use neuromodulation techniques to interfere with nerve signals to delay an ejaculation. When deactivated, the elements would not interfere with nerve signals.

Nonin Medical invented finger pulse oximetry and is a global leader in developing highly accurate noninvasive medical monitoring solutions that improve the quality of people's lives. Technology driven, we provide pulse and cerebral oximeters, capnographs, sensors, OEM/eHealth, and veterinary solutions that meet customers'​ needs today and tomorrow. Nonin Medical is headquartered in Plymouth, Minnesota, USA, and has an additional customer service center in Amsterdam, the Netherlands. We sell our products to clinicians and consumers in more than 125 countries and have more than 200 OEM partners worldwide. BUY AMERICAN QUALITY. For more information, call (800) 356-8874 (toll free US and Canada) or +1 763.553.9968. Email: info@nonin.com or infointl@nonin.com. Or visit nonin.com. Vision To improve the quality of people’s lives throughout the world by expanding the capabilities of noninvasive measurements. Mission To provide a diverse portfolio of simple, noninvasive measurements that lowers the cost of care and empowers individuals and caregivers to make better decisions. These solutions will be high quality, high performance, and easy to use. Values ■ Quality – We thrill our customers by providing the finest experience. We anticipate their needs. ■ Agility – We are fast, agile and focused. We creatively drive change. ■ People – We care about our people, foster learning and provide opportunities for growth. ■ Community – We care about supporting our communities and the lives of others. ■ Integrity – We are honest, ethical and dedicated to doing the right thing.

Nortech Systems is a leading provider of design and manufacturing solutions for complex electromedical devices, electromechanical systems, assemblies, and components. Nortech Systems primarily serves the medical, aerospace & defense, and industrial markets. Its design services span concept development to commercial design, and include medical device, software, electrical, mechanical, and biomedical engineering. Its manufacturing and supply chain capabilities are vertically integrated around wire/cable/interconnect assemblies, printed circuit board assemblies, as well as system-level assembly, integration, and final test. Headquartered in Maple Grove, Minn., Nortech currently has seven manufacturing locations and design centers across the U.S., Latin America, and Asia. Nortech Systems is traded on the NASDAQ Stock Market under the symbol NSYS. Nortech’s website is www.nortechsys.com.

Nuvaira was established in 2008 to address unmet clinical needs in the treatment of overactive airway nerves, a common disease feature of both COPD. The company offers innovative COPD therapies to help preserve patient lung health with a catheter-based system used to treat overactive airways.

We are Nuwellis, (Nasdaq: NUWE) formerly CHF Solutions. Our solutions go beyond chronic heart failure, so we've rebranded to reflect our therapeutic focus areas: heart failure, critical care, and pediatric fluid imbalance. We are a medical device company dedicated to transforming the lives of patients suffering from fluid overload through science, collaboration, and innovation. Our Aquadex SmartFlow® System gently removes fluid from adult and pediatric patients weighing 20 kg or more. Nuwellis consists of a purpose-driven team that puts patients and their providers at the center of everything we do. This is the new well. And for those whose lives and life's work are transformed by our fluid management technologies, the new well is everything. Nuwellis is headquartered in Eden Prairie, Minn., with a wholly-owned subsidiary in Ireland. The Company has been listed on the Nasdaq Capital Market since February 2012, previously branded as CHF Solutions (Nasdaq: CHFS).

Objective Biotechnology's mission is to develop high-impact technologies that enable comprehensive measurement and manipulation of biological systems at multiple scales, unlocking new research capabilities.

Pace® Science and Technology Company makes the world a safer, healthier place. We partner with clients to provide the service, science, and laboratory data needed to make critical decisions that benefit us all. Through a nationwide laboratory network, Pace® advances the science of businesses, industries, consulting firms, government agencies, and others. ANALYTICAL SERVICES Pace® Analytical Services is a division of Pace® Science and Technology, providing local testing and analytical services backed by a large, national laboratory and service center network. Through in-lab, mobile, and emergency onsite containment and regulatory services, we ensure our air, water, soil, and more are safe for our communities and lives. LIFE SCIENCES Pace® Life Sciences is a division of Pace® Science and Technology committed to advancing the science of the pharmaceutical and biopharmaceutical industry by providing full-service CDMO/CRO capabilities and professional services for in-house labs through a nationwide network of service centers, manufacturing sites, and FDA-registered laboratories. COMMITMENT We believe the work our customers do is important to improving our communities and lives and are committed to supporting them through strong partnerships, delivering upon expectations, and providing exceptional customer service.

Peytant Solutions, Inc. (PSI) is a medical device company, incorporating Regenerative Human Biomaterial   with  absorbable and alloy implant technologies. Our percutaneous, biologic AmnioStent...

Since 1989 ProMed has been recognized as a leading Contract Manufacturer of complex, intricately designed molded silicone and plastic components and assemblies for highly regulated industries. ProMed's expertise lies in applications for short-term and long-term implantable devices, drug-releasing combination devices, and specialized manufacturing for aerospace, defense, and automotive applications. We collaboratively work with our customers from prototype through production, providing over 30 years of experience related to design for manufacturability, material selection, tooling/fixturing, process development, manufacturing, and other value-added services that result in cost-effective solutions with superior quality. With four facilities spanning more than 134,000 sq/ft of office, laboratory, and Class 7 Manufacturing space, ProMed's in-house services include tooling design and manufacturing, quick turn prototyping, injection and transfer molding of components, micro molding of tightly tolerance components, insert over molding, advanced material blending of specialty additives, automated assembly, testing support for drug delivery and combination devices, as well as customized packaging services.

RespirTech, a Philips company, works with healthcare teams, patients and caregivers to provide effective airway clearance therapy with the Philips InCourage system and Philips Respironics CoughAssist T70. Our dedicated customer care team contributes to improved management of chronic respiratory conditions like cystic fibrosis, COPD, bronchiectasis and certain neuromuscular and neuromotor diseases. RespirTech's innovative products and exceptional service supports patients on their journey to better breathing. Respiratory Technologies, Inc., dba RespirTech, was founded in 2004 and acquired by Philips in 2017.

RxFunction®, Inc. is a medical device company with a mission to design and market medical technologies that improve balance, increase mobility, and enhance confidence for patients. Walkasins® Lower Limb Sensory Prosthesis is clinically proven to improve gait and balance, and reduce the risk of falls. Walkasins replaces part of the lost nerve function for the feet. It is intended for individuals who experience numbness in their feet and struggle with mobility problems due to peripheral neuropathy. Walkasins is only available by prescription. To learn more, please visit us at www.rxfunction.com. RxFunction created Walkasins by building upon patented technology developed by co-founder and scientist Lars Oddsson, PhD. Development of Walkasins was supported by Small Business Innovation Research grants from the National Institutes of Health and is manufactured in Minnesota. RxFunction is the exclusive provider and manufacturer of Walkasins. Caution: Individual results and activity levels while using Walkasins may vary depending on many factors. There are risks associated with the use of this product and there are certain individuals who should not use the product. Only a qualified clinician can tell you if this product is appropriate for you and your individual circumstances. Please consult with your healthcare team for complete information regarding benefits, risks, and possible outcomes.

As an emerging leader in the development and commercialization of energy transfer technology, SANUWAVE® presents products that help expedite wound healing on a cellular level. SANUWAVE's easy-to-use ENERGY FIRST® product portfolio works to help heal some of the most difficult, stalled, or hard-to-heal wounds by activating the body's normal regenerative process using an assortment of energy waves, from shockwaves to ultrasound. SANUWAVE values patient comfort and the importance of wound healing, recognizing its' value to not only improve patient quality of life but to help avoid further complications that could lead to amputation or even lives lost. SANUWAVE's minimally to completely non-invasive technologies can help wounds heal with little to no pain or discomfort. Most treatments can be done in under ten minutes, however, results may vary depending on wound size and patient response to treatment. The UltraMIST System delivers low-frequency ultrasound to the treatment site using a noncontact fluid (e.g., saline). MIST Systems produce a low energy ultrasound-generated mist used to promote wound healing through wound cleansing and maintenance debridement by the removal of fibrin, yellow slough, tissue exudates, and bacteria. The MOA includes control of inflammation, augmentation of local tissue perfusion, wound bacteria and bacterial biofilm reduction, increased angiogenesis, and more. The dermaPACE System is an advanced wound care device that utilizes pulsed acoustic cellular expression (PACE®) technology, a proprietary form of focused, extracorporeal shockwaves. It is the first shockwave system to be FDA-cleared for the treatment of diabetic foot ulcers (DFU). For general inquiries, please email: info@sanuwave.com

SecondWave Systems is a pioneer in the emerging field of bio-ultrasonic medicine. The company is developing a first-of-its-kind noninvasive, wearable ultrasound stimulation platform that will give patients and their physicians a new option for treating debilitating or life-threatening disease.

ShiraTronics is a forward-thinking medtech startup committed to revolutionizing the field of migraine medicine with our minimally invasive neuromodulation system. Our mission? To transform the lives of those facing Chronic Migraine by reducing headache days and restoring quality of life.

Starkey is a privately held, global hearing technology company headquartered in Eden Prairie, Minnesota, USA. We are recognized for our innovative design, development and distribution of comprehensive digital hearing systems. We develop products using an evidence-based design approach, meaning that rigorous testing takes place to prove the benefits of a new technology or algorithm before a hearing aid is ever fit on a patient. Every Starkey employee is committed to helping people on their journey to better hearing every day. Starkey operates 25+ facilities and conducts business in more than 100 markets worldwide. We develop, manufacture and distribute hearing aids via three distinct brands - Audibel, NuEar and our original brand, Starkey. Learn more about us on our blog: www.starkey.com/blog

Stimdia Medical, Inc., is a privately held company headquartered in Minneapolis, MN and has developed the pdSTIMTM System, a minimally invasive, temporary, neuromuscular stimulation system which has received FDA Breakthrough Device Designation. Mechanical ventilation (MV) is considered to be a lifesaving treatment in patients suffering respiratory failure to achieve sufficient pulmonary gas exchange. However, prolonged MV can promote atrophy and contractile dysfunction of the primary muscle utilized in respiration, the diaphragm. Significant loss in muscle mass results in a reduction in diaphragmatic function and compromises the ability of patients to breath on their own. The pdSTIM System was designed to awaken and restore the integrity of the diaphragm muscle in patients who are on MV. This is accomplished with the use of subcutaneously inserted temporary leads connected to the pdSTIM console and utilizes the proprietary RespiSyncTM sensing and stimulation algorithms to coordinate phrenic nerve stimulation with physiologic diaphragmatic movement in synchrony with mechanical ventilators. The pdSTIM System has not yet received regulatory clearances or approvals and is not currently for sale in any country.

STI has been a pioneer in medical contracting since 1981. Today, we continue as a leader, expanding our resources to better serve you, our customer. From the initial contact to the final development of your product, we enforce rigid, industry leading standards. This commitment has earned STI an international reputation for dependable contract packaging, responsive service, and the ability to adapt to the ever-changing needs of the healthcare industry. Our STI team specializes in LEAN manufacturing which results in increased capacity, cost savings and work cell efficiency.

Surmodics is the global leader in surface modification technologies for intravascular medical devices and a leading provider of chemical components for in vitro diagnostic (IVD) immunoassay tests and microarrays. Surmodics is pursuing highly differentiated medical devices that are designed to address unmet clinical needs and engineered to the most demanding requirements.

ZOLL Medical is a medical devices company that specializes in healthcare technology for emergency response, with a focus on cardiac care and resuscitation.