List of Biosimilars Companies in Canada - 6

Biocure Technology Inc. is a biopharmaceutical company comprised of leading scientists specializing in the development and commercialization of its own CAR T-cell therapy, targeting Chronic lymphocytic leukemia and solid tumor cancers. Additionally, the Company is developing Biosimilar technologies for cancer treatment. The CAR T-cell cancer therapy space is one of the most innovative cancer treatments currently in the market and is seeing huge global interest. Founders and management are driven by a social agenda aimed at providing a global answer to highly priced biological medicines that remain outside the reach of common people. The company has unique scientific and execution skills to address the high barriers of CAR-T cell therapy and Biosimilar technologies, therefore is well positioned to gain leadership in the rapidly growing market of CAR T-cell cancer therapy.

Juno Pharmaceuticals Canada sources, develops, and delivers life saving specialized pharmaceutical products for Canadian patients. Our colleagues work with trusted partners to co-develop novel drug delivery mechanisms that satisfy untapped market demand, first to market generic products, biosimilar offerings, and patent challenge strategies. Juno's portfolio consists of both branded and generic drug assets in multiple presentation forms including injectable drugs (vials, amps, & pre filled syringes), complex biosimilars, ophthalmic products, oral does tablets and capsules, prescription dermatology topicals, and other unique dosage systems. Our team have deep roots into the Canadian hospital space, retail pharmacy market, specialty channels, and a robust B2B platform. In addition, Juno Canada has recently embarked with product sourcing in the animal health space and remain focused on opening new delivery channels and customer groups to facilitate supply for Canadian patients. Juno is proud to supply 5 molecules deemed medically necessary by the World Health Organization on their critically essential medications list, and we are actively pursuing export opportunities to countries in need of our critical medications. To learn more about Juno Pharmaceuticals Canada please contact us at communications@junopharm.com For sales enquiries contact us at sales@junopharm.com

Microbix Biosystems Inc. develops and commercializes proprietary biological and technological solutions for human health and wellbeing. We manufacture a wide range of biological materials for the global diagnostics industry, notably antigens used in immunoassays and Quality Assessment Products (QAPs™). In 2021 we launched our first Viral Transport Medium, branded as DxTM. Microbix’s business of producing high-quality viral and bacterial preparations stems from over three decades of experience in the field, including strain selection, reliable and efficient organism culture at scale, purification, and pathogen inactivation. As a result of Microbix’s expertise, its products have received widespread and longstanding customer acceptance, with continuing growth in demand. Microbix’s current catalogue of biological preparations covers a range of pathogens that are implicated in maternal, pediatric, childhood, respiratory, sexually transmitted, and insect-borne diseases. Microbix also applies its biological expertise to develop other innovative and proprietary technologies and products. Our development project pipeline currently includes Kinlytic® Urokinase, a biologic thrombolytic drug used to treat blood clots.

Optimi Health exists to grow psychedelic science and medicine as an industry-leading supplier of natural, pharmaceutical-grade psilocybin and synthetic psychedelic compounds. Our Purpose is to produce scalable, natural mushroom formulations and other psychedelics for transformational human experiences. Our Goal is to be the number one trusted, compassionate supplier of safe, natural EU-GMP-grade psilocybin and synthetic psychedelics across the world. Our Promise is to make possible a future whereby psychedelic alternatives aid a wide variety of mental health conditions.

PlantForm Corporation is a Canadian biotech company with a low-cost, proprietary manufacturing platform for a wide range of plant-made pharmaceuticals, including monoclonal antibodies, therapeutic proteins and vaccines for the treatment of cancer, HIV/AIDS, Ebola virus and other life-threatening illnesses. The company’s vivoXPRESS® plant-based technology platform produces biopharmaceutical products in fully contained greenhouse environments. PlantForm’s pipeline features both innovator and biosimilar products, including: • 3 biosimilar cancer drugs, leading with trastuzumab, a plant-produced version of the breast cancer drug Herceptin® • innovator antibodies for HIV/AIDS, funded by the Government of Canada and the Bill & Melinda Gates Foundation • innovator antibodies for treatment of Ebola virus (Sudan strain), with financial support from the National Research Council of Canada Industrial Research Assistance Program (NRC-IRAP) and in collaboration with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) • recombinant butyrylcholinesterase (BuChE), an enzyme used as preventative medicine for people vulnerable to attack by nerve agents, organophosphates or other stimulants. PlantForm is interested in establishing partnerships with other companies to develop additional targeted biosimilar and innovator drugs.

Somru BioScience is an emerging biotechnology company dedicated to developing breakthrough antibody technology for research, diagnostic and therapeutic applications.