List of Biologics Companies in Minnesota - 15

Cytotheryx is a platform technology company focused on the development of a high-quality, consistent source of primary human hepatocytes (PHH), the functional cells of the liver. Based in Rochester, Minnesota, Cytotheryx is using innovative technology to increase the supply of available cells for use by pharmaceutical companies, biotechnology companies, and academic research institutions. Primary human hepatocytes are used widely in research, making them vital to continued scientific and therapeutic breakthroughs. However, a limited supply of liver cells prevents ongoing growth. Cytotheryx is opening doors for how we treat liver disease, develop therapeutics, advance research, and beyond.

DiaMedica Therapeutics is a clinical-stage biopharmaceutical company that is developing innovative treatments where there is significant unmet clinical need or where no current therapies are available with the focus on neurological and kidney diseases.

Donaldson Company helps solve some of the world's most complex filtration and contamination control challenges. As a global leader in the filtration industry, we pride ourselves on our innovative technologies and solutions, backed by a talented and dedicated team of employees. Our filtration technologies and products are used every day in a variety of industries and environments, including aerospace, agriculture, construction, food and beverage, manufacturing, mining, power generation, transportation and many more. Our success comes from our 14,000+ employees, the support our customers receive, and more than 140 manufacturing and distribution centers on six continents.

IGF Oncology, LLC Our Mission: IGF Oncology is developing novel cancer drugs that have better efficacy and lower side effects than existing cancer chemotherapy drugs.

Imanis Life Sciences has an unwavering commitment to the advancement of science. For many companies, profitability rules decision making. But at Imanis, leading scientific breakthroughs is the primary focus. We are about making a difference in the world by putting people in a better position than they were yesterday. We strive to do this by being a leader in laboratory assays and research services to accelerate the development of a broad range of next-generation therapies.

InSitu Biologics is an emerging biotech company focused on development of a multi-phase prolonged release drug delivery platform for localized treatment of pain, cancer, and infection. We use disruptive technology to address unmet needs in the pain management and drug delivery markets.

LEAH Laboratories is a biotechnology company that specializes in building living therapies for pets and their people.

Luminary is a clinical stage CAR-T therapy company with a novel allogeneic manufacturing platform where our CAR and or TCR development utilizes gamma delta cells. What makes our allogeneic therapeutics unique are that our final drug product includes the combinatory power of both the Vẟ1 and Vẟ2 gamma delta cells giving our therapies the power of both innate and adaptive cancer clearing power. We have multiple solid tumor targets under development with a proprietary signaling method to ensure T-Cell persistence. Additionally, our Ligand BAFF CAR for hematologic cancers is designed with 3 antigen receptors specifically designed to overcome antigen escape.

NeuroOne Medical Technologies is a medical device company that specializes in developing high-definition, minimally invasive thin film electrodes for the diagnosis and treatment of various neurological conditions.

Recombinetics is a global leader in proprietary gene repair and gene-editing technology. Our breakthrough scientific research and development of TALEN and CRISPR (Cas9) gene editing technologies has resulted in breakthroughs in the regenerative medicine, disease research and animal agriculture. Led by a team of expert geneticists, genome engineers, and reproductive physiologists, the company is headquartered in St. Paul, Minnesota.

Rion is a clinical-stage regenerative medicine company focused on developing innovative exosome therapeutics that are clinically impactful, accessible, and practical for any patient, anywhere. Rion has developed Purified Exosome Product (PEP), an innovative biologic platform that optimizes the therapeutic power of exosomes for regenerative medicine.

ScaleReady is a consulting company that specializes in providing strategic planning and organizational development services to help businesses scale and achieve growth.

SilkTech Biopharmaceuticals develops silk-based anti-inflammatory therapies. Our lead indication is in Dry Eye Disease, an inflammatory based chronic condition.

Syntiron LLC, is dedicated to developing innovative vaccines for humans. Our patented microbial antigen discovery and purification technology targets proteins that acquire iron, a critical nutrient that is required for survival of the bacteria. These proteins are expressed on the cell surface and are similar among different strains, making them ideal vaccine antigens. Our proprietary platform enables rapid identification of these proteins, which can then be directly extracted from the host cell or produced recombinantly for preclinical vaccine development.

Tychon Biosciences is a biotechnology company commercializing novel technology in the rapidly expanding Immuno-oncology marketplace that offers similar high-specificity cancer killing relative to recently-approved cancer therapies, yet with increased safety and decreased cost. Using Tychon’s BiND platform, a first-in-class bi-specific nanoring platform as an immediate therapy that targets both an antigen receptor on a cancer cell, and T-cell—binding them together and allowing your T-cells to attack cancer cells naturally without the need for genetic engineering.