List of Bioinformatics Companies in Netherlands - 7

Bespoke promoters and enhancers, for any tissue, any organism. At Annogen, our vision is a future where safe and effective advanced therapies are specifically expressed in the right tissues with no off-target effects. We believe that this can be achieved by bespoke promoters (genetic switches) and genomic expression sites. Therefore, Annogen is on a mission towards becoming the leading expertise center for gene expression engineering in order to improve the safety and effectiveness of tomorrow's cell and gene therapies. Annogen leverages its proprietary SuRE™ technology to identify regulatory DNA elements to be used for controlled (therapeutic) gene expression for gene & cell therapy, as well as for recombinant protein and virus production. In addition, we develop service projects based on our proprietary AIM™ technology to identify favorable gene insertions and their expression levels for more than 100,000 integrations in parallel. These approaches typically enable big improvements in any biomedical strategy involving the (over-) expression of genes. Annogen was founded in 2017 by Dr. Joris van Arensbergen, who developed and published the SuRE™ technology as a post-doctoral fellow in the laboratory of Prof. Dr. Bas van Steensel at the world-renowned Netherlands Cancer Institute (NKI). Today, Annogen is the trusted partner for bespoke gene expression engineering for leading biopharmaceutical, agricultural and academic research centers globally.

ENPICOM is an innovative bioinformatics software engineering company committed to accelerating biologics discovery and development through cutting-edge bioinformatics solutions. With a deep understanding of biology, software engineering, and AI, ENPICOM delivers innovative tools that empower scientists to make groundbreaking discoveries faster and more accurately. For more information visit enpicom.com.

Genetwister is an innovative Dutch biotechnology company founded in 1998 specialized in molecular breeding and bioinformatics of agricultural, horticultural and ornamental plants. Through our research projects we help our customers improve crop quality to enable more sustainable farming and a more reliable food supply for the future. Our shareholders are five internationally renowned vegetable and ornamental breeding companies we are proud to serve.

Kyazma® focuses on genetic linkage analysis in diploid experimental populations.

Over the past decade we have transformed into a focused leader in health technology. At Philips, our purpose is to improve people’s health and well-being through meaningful innovation. We aim to improve 2.5 billion lives per year by 2030, including 400 million in underserved communities. We see healthcare as a connected whole. Helping people to live healthily and prevent disease. Giving clinicians the tools they need to make a precision diagnosis and deliver personalized treatment. Aiding the patient's recovery at home in the community. All supported by a seamless flow of data. As a technology company, we – and our brand licensees – innovate for people with one consistent belief: there’s always a way to make life better. Visit our website: http://www.philips.com/ Follow our social media house rules https://www.philips.com/a-w/about-philips/social-media.html

Scinvivo enables optical biopsy for bladder cancer diagnostics. Current imaging techniques for bladder cancer have their limitations, as they only enable the urologist to visualise the bladder wall surface. In 30% of the cases, healthy tissue is incorrectly classified as cancerous. Another limitation is that it is difficult to fully remove a tumor during a surgical procedure, as the borders of the tumor are difficult to visualize. The last limitation is that it is impossible to determine the invasion depth of the tumor with current imaging technologies, while the invasion depth has major impact on the proposed treatment. All these limitation lead to unnecessary, invasive, and costly interventions. Scinvivos technology enables the urologist to improve diagnosis, and thus decreasing the amount of interventions, patient burden, and costs.

The Hyve is the data & informatics service provider for life science organizations looking to align their data infrastructure with their research needs. We provide services regarding biomedical informatics solutions to most of the top 20 biotech and pharmaceutical companies, hospitals, universities, and medical centres in the United States and Europe, including Dana Farber Cancer Institute in Boston and King’s College London. We also collaborate with biobanks, registries, and patient organisations around the world. Our mission is to enable open science by developing and implementing open-source solutions and FAIRifying data in life sciences. We have ample experience with open-source tools such as cBioPortal, Open Targets, OHDSI/OMOP, RADAR-base, and Fairspace. The Hyve can also advise on practical application and implementation of the FAIR data principles, including semantic modelling, data landscaping, and knowledge graph creation.