List of Bioinformatics Companies in Canada - 34

Founded in 2017, 48Hour Discovery (48HD) has a powerful technology platform for peptide-based drug discovery. We are reducing the cost, time, and risk of developing new therapies with our innovative target screening strategy to quickly identify the best and most promising drug leads.

Ability Biologics is dedicated to developing innovative, targeted, immune modulating biotherapeutics to address unmet medical needs in patients with cancer and autoimmune diseases. The company utilizes its powerful AbiLeap™ discovery engine, which combines massively parallel, continuously learning AI with advanced cell targeting technology, to develop the most potent and selective antibody therapeutics for areas of great unmet need.

We apply proprietary computational tools to bacterial metabolomic and genomic data in order to identify, isolate, and assay novel drug-like small molecules in high-throughput to expedite the search for medicines that will better protect us from a wide spectrum of diseases.

We use next-gen machine learning to find novel psychedelic drug compounds. Classical (first-generation) psychedelics have never been optimized to treat any disease and so we aim to design compounds with the optimal risk-benefit ratio in various indications. Beyond mental health, we focus on neurodegeneration and neural injuries, increasing brain longevity and extending human mental healthspan.

Aspect Biosystems is a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform the treatment of currently incurable diseases. Aspect is creating these next generation cell therapies by applying its full-stack tissue therapeutic platform, which combines the company’s proprietary bioprinting technology, therapeutic cells, biomaterials, and computational design. Aspect’s bioprinted tissue therapeutics are designed to replace, repair, or supplement biological function inside the body with the aim of treating currently incurable diseases such as type 1 diabetes as well as genetic and acquired liver diseases.

Cancer doesn’t wait — so we shouldn’t either. At Avitia, we’re making sure that clinical labs and oncologists everywhere have the tools they need to diagnose, as well as treat cancer faster. Our AI/ML technology ensures partners have cost-effective NGS-based molecular testing solutions that provide rapid turnaround times. Now, we empower healthcare teams to skip the delays and focus on what matters — personalized patient care. From pinpointing cancer mutations to streamlining clinical trial access, we’re here to make precision oncology accessible for every community and improve patients’ quality of life. Let’s transform cancer care together. Le cancer n’attend pas, et nous ne devrions pas non plus attendre. Chez Avitia, nous veillons à ce que les laboratoires cliniques et les oncologues du monde entier disposent des outils dont ils ont besoin pour diagnostiquer et traiter le cancer plus rapidement. Notre technologie IA/ML garantit à nos partenaires des solutions de tests moléculaires NGS rentables qui offrent des délais d’exécution rapides. Désormais, nous permettons aux équipes de soins de santé d’éviter les retards et de se concentrer sur ce qui compte : des soins personnalisés aux patients. De l’identification des mutations cancéreuses à la rationalisation de l’accès aux essais cliniques, nous sommes là pour rendre l’oncologie de précision accessible à toutes les communautés et améliorer la qualité de vie des patients. Transformons ensemble les soins contre le cancer.

BugSeq is an online bioinformatics platform for automated microbiology sequencing analysis. Simply upload your raw data, and our evidence-based pipelines will return actionable reports.COVID-19: (08/2021) SARS-CoV-2 detection with nanopore sequence data.

Chemical Computing Group (CCG) is a Montreal-based software company that specializes in computational chemistry, bioinformatics, and cheminformatics solutions. Founded in 1994, CCG has over 30 employees and operates globally with support offices in North America, Europe, and Asia. The company focuses on developing tools for molecular modeling, simulations, and machine learning to enhance drug discovery and life sciences research. CCG's primary products include the Molecular Operating Environment (MOE), a comprehensive platform for drug discovery that integrates visualization, molecular modeling, and cheminformatics. Another key product is PSILO, a protein structure database system designed for managing macromolecular data. CCG also provides academic support through discounted software licenses for non-profit institutions and sponsors research awards to recognize excellence in computational chemistry. The company collaborates with various scientific partners to refine methodologies and expand application areas. CCG serves a diverse clientele, including leading pharmaceutical and biotechnology companies, as well as academic institutions worldwide.

Compugen is a clinical-stage therapeutic discovery and development company utilizing its broadly applicable predictive computational discovery capabilities to identify new drug targets and biological pathways for developing cancer immunotherapies. Compugen has developed two proprietary product candidates: COM701, a potential first-in-class anti-PVRIG antibody and COM902, a potential best-in-class antibody targeting TIGIT for the treatment of solid tumors. Compugen also has a clinical stage partnered program, rilvegostomig (previously AZD2936), a PD-1/TIGIT bispecific antibody where the TIGIT component is derived from Compugen’s clinical stage anti-TIGIT antibody, COM902, in Phase 3 development by AstraZeneca through a license agreement for the development of bispecific and multispecific antibodies. In addition, the Company’s therapeutic pipeline of early-stage immuno-oncology programs consists of programs aiming to address various mechanisms of immune resistance, of which the most advanced program, COM503, is in IND enabling studies is licenced to Gilead. COM503 is a potential first-in-class, high affinity antibody which blocks the interaction between IL-18 binding protein and IL-18, thereby freeing natural IL-18 in the tumor microenvironment to inhibit cancer growth. Compugen is headquartered in Israel, with offices in San Francisco, CA. Compugen’s shares are listed on Nasdaq and the Tel Aviv Stock Exchange under the ticker symbol CGEN.

Decipher Biosciences, formerly GenomeDx, is a genomic information company headquartered in Vancouver, British Columbia, with laboratories in San Diego, California.

Deep Genomics is using artificial intelligence to build a new universe of life-saving genetic therapies. The future of medicine will rely on artificial intelligence, because biology is too complex for humans to understand. At Deep Genomics, our geneticists, molecular biologists and chemists develop new ways of detecting and treating disease using our biologically accurate artificial intelligence technology.

VAL-083 is a small-molecule chemotherapeutic that benefits from extensive clinical research sponsored by the US National Cancer Institute, and is currently approved as a cancer therapy overseas. Efficacy has been demonstrated in a range of tumor types, including glioblastoma multiforme (GBM), the most common and aggressive form of brain cancer. Del Mar Pharma has filed an IND with the USFDA to initiate a dose-escalating Phase II clinical trial in refractory GBM, a major market opportunity.

A newly established NewCo developing therapeutics targeting a novel class of tumour-specific antigen.

IFOWONCO uses advanced computational modelling techniques coupled with state of the art machine learning to rapidly identify and optimize drug candidates.

ImmVue Therapeutics is a company that develops small-molecule screen KISMEHT to identify allosteric modulators of the kinase family. Its lead compounds use lymphocytes and aim to revert patients to their vibrant selves with innovative medicines that target novel mechanisms to revitalize their immune system.

InMed Pharmaceuticals is a pharmaceutical company focused on developing a pipeline of proprietary small molecule drug candidates targeting the CB1/CB2 receptors. InMed’s pipeline consists of three drug development programs in the treatment of Alzheimer’s, ocular and dermatological indications. Together with our subsidiary BayMedica, we are a global leader in the manufacturing, development and commercialization of products based on rare cannabinoids and their proprietary, small molecule drug analogs. For more information, visit www.inmedpharma.com. Nasdaq: INM

Marea Therapeutics is a clinical-stage biopharmaceutical company focused on developing and commercializing small molecules to address hypertriglyceridemia and other metabolic diseases.

Moss is a disrupter in the consumer healthcare space offering personalized health and gut health solutions guided by genomic data, microbiome data, and clinically validated assessments. Founded in 2018, Moss is a technology and healthcare integrator for personalized health and offers a comprehensive line of probiotics and nutritional supplements.

NetraMark combines proprietary QML/ML algorithms with cross-domain expertise to bring ML commercialization into reality, starting with the pharmaceutical space in drug development where we utilize large and small data in order to help pharmaceutical companies understand their patient populations better. Our technology allows for the utilization of phase II data in order to optimize phase III trials from the vantage of their specific patient population.

Noze is the global leader in digital odor perception (often hailed as the digital equivalent of the sense of smell). We have developed the world's most advanced digital nose, capable of detecting and identifying odors in real-world settings with unparalleled accuracy. Leveraging cutting-edge machine intelligence and a sensor developed with exclusively licensed NASA technology, Noze is committed to enhancing human health and wellbeing. Our mission is to improve patient outcomes by enabling real-time disease detection at any point-of-care by using our technology to target breath-based odor biomarkers.

At PhenoTips we are dedicated to providing you with software and services that bring your workflow into the modern age of genomics. PhenoTips is based in Toronto, North America’s fastest-growing tech hub, just steps from the MaRS Discovery District and leading healthcare institutions. Surrounded by innovation, we are inspired to challenge the status quo of medical care in genetics, working towards a future in which patient data is unified and usable, rather than siloed in EHR systems and hospital filing cabinets. Our mission is to empower clinicians to provide life-saving, personalized care to patients through our complete Genomic Health Record that fills in the gaps left by Electronic Health Records, making clinical data complete, standardized, shareable, and interoperable.

ProMIS Neurosciences, Inc. is a leading development-stage biotechnology company based in Toronto, Ontario and Cambridge, Massachusetts. The company is focused on the treatment of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple system atrophy through the development of antibody therapeutics and diagnostics. ProMIS Neurosciences is publicly traded on the Toronto Stock Exchange.

ProMIS Neurosciences is focused on the treatment of Alzheimer’s disease, amyotrophic lateral sclerosis and multiple system atrophy through the discovery and development of antibodies selective for toxic misfolded proteins driving these diseases.

ProteinQure is a biotech company focused on the design of novel exotic peptides with broad therapeutic applications. Powered by atomic-level simulations and artificial intelligence, we design dynamic peptides that take drugs straight to their target – outperforming other treatment delivery systems. By daring to deliver therapeutics in a novel way we are changing the game for drug development and bringing hope to patients with previously untreatable diseases. At ProteinQure, we pride ourselves on our unique, diverse and cross-disciplinary team that brings together experts from experimental & computational biology, machine learning and software engineering.

PulseMedica has developed a proprietary real-time 3D imaging and laser targeting system for precise retinal surgery. Our patented next generation ultrafast femtosecond laser ophthalmic treatment will enable treatment for retinal diseases such as age-related macular degeneration (AMD) and glaucoma, for which there is currently no cure. PulseMedica is a company based out of Edmonton, AB, Canada.

Rakovina Therapeutics Inc. engages in the research and development of new cancer treatments based on a novel series of small-molecule DNA-damage response inhibitors. The company focuses on utilizing Deep Docking™ AI to target DNA-damage response (DDR) for oncology-focused treatments. Their target markets include breast cancer, ovarian cancer, and prostate cancer.

Ranomics offers high throughput solutions for protein engineering, drug discovery, genomics research and synthetic biology. Using our VariantFind and VERG genomics platforms, Ranomics offers partners the a scalable solution to engineer and screen genetic variants in a wide range of model organisms. Our industry leading DNA Variant libraries and high-throughput cell assays help researchers to hit their research objectives faster and with better results than traditional methods. Over the years, we have worked with top biotech and pharma companies in the US and worldwide. Our partners have used our technologies to advance their R&D and drug discovery projects, and to publish papers in Nature Biotechnology, mAbs, and other journals.

Rapid Novor Inc. is the world's leader in antibody protein sequencing technology. Specializing in the field of mass spectrometry-based proteomics, the team has developed the technology to directly sequence antibody proteins without needing to access the producing cell line. As a University of Waterloo spin-off, the company is building its technology portfolios based on the twenty years of scientific research and inventions from Dr. Bin Ma, co-founder and chief scientist. The company's REmAb™ antibody protein sequencing service has allowed for the accurate sequencing of any given antibody proteins on a routine basis. The company's WILD™ service is the first commercially available service that can accurately distinguish the isobaric Isoleucine and Leucine using mass spectrometry. The company's mission is to advance life science for better human health with next generation protein sequencing. For more information, visit www.rapidnovor.com. Follow the company on Twitter @rapidnovor.

Segra is a biotechnology company that specializes in industrial-scale plant micropropagation also known as “plant tissue culture.” The company is developing industrial-scale micropropagation laboratories to produce healthy, robust plantlets for growers and licensed cannabis producers globally. Our solution: Segra leverages expertise in plant tissue culture, biochemistry, botany, genetic testing, and production under strict regulatory environments to bring end-to-end solutions for product production and sale in the agriculture space. Investors: info@segra-intl.com

We address the inefficiency of clinical trial success that is currently at >90% failure rate. Simmunome is at the leading edge of leveraging AI towards unraveling biological complexity. We transform physiological systems into biologically representative computational models for use in therapeutic and preventative drug discovery. Despite the significant technological advances in biotechnology, high-throughput methods, and computational biology over the last 20 years, it has proven difficult to gain meaningful insights that translate into truly disruptive medicines. We combine fragmented data to create holistic models of disease that translate to helping you understand your drug's mechanism of action, increase efficacy in the right target population and predict your drug's safety profile. Ultimately getting you to market faster, reducing your R&D costs, and dramatically increasing your probability of success.

Valence Labs is a biotechnology company that specializes in AI-driven drug discovery. It operates as a semi-autonomous research and productization engine within Recursion Pharmaceuticals. The company focuses on leveraging deep learning applications to enhance drug development, particularly for complex diseases. Valence Labs develops software tools that accelerate therapeutic research, including novel target identification and molecular design. In addition to its AI-driven initiatives, Valence Labs is associated with a separate entity that specializes in active pharmaceutical ingredient (API) synthesis. This division offers custom API manufacturing services, including process development and GMP-compliant commercial-scale production. Valence Labs collaborates with biotech partners to provide AI solutions, emphasizing complex chemistry and preclinical optimization.

Willow Biosciences is a biotechnology company focused on the development of a disruptive bio-based process for the production of high purity cannabinoids. Its Burnaby lab houses state-of-the-art molecular biology, tissue culture, plant cultivation and analytical chemistry capabilities focused on correlating the physical and chemical characteristics of cannabis plants with their unique genetic makeup.

Zymeworks is a global clinical-stage biotechnology company committed to the discovery, development, and commercialization of novel, multifunctional biotherapeutics. Zymeworks’ mission is to make a meaningful difference in the lives of people impacted by difficult-to-treat cancers and other diseases. The Company’s complementary therapeutic platforms and fully integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly differentiated antibody-based therapeutic candidates. Zymeworks engineered and developed zanidatamab, a HER2-targeted bispecific antibody using the Company’s proprietary Azymetric™ technology. Zymeworks has entered into separate agreements with BeiGene, Ltd. (BeiGene) and Jazz Pharmaceuticals Ireland Limited (Jazz), granting each exclusive rights to develop and commercialize zanidatamab in different territories. Zanidatamab is currently being evaluated in multiple global clinical trials as a potential best-in-class treatment for patients with HER2-expressing cancers. The U.S. FDA granted accelerated approval of Ziihera® (zanidatamab-hrii) 50mg/mL for injection for intravenous use for the treatment of adults with previously-treated, unresectable or metastatic HER2-positive (IHC 3+) biliary tract cancer (BTC). Ziihera is the first and only dual HER2-targeted bispecific antibody approved for HER2-positive BTC in the U.S. A BLA has also been accepted for review by the Center for Drug Evaluation (CDE) of the National Medical Products Administration (NMPA) in China. Zymeworks is rapidly advancing a robust pipeline of wholly-owned product candidates, leveraging its expertise in both antibody-drug conjugates and multispecific antibody therapeutics targeting novel pathways in areas of significant unmet medical need. Phase 1 studies for ZW171 and ZW191 are now actively recruiting with investigational new drug applications for ZW220 and ZW251 planned for 2025.