List of Artificial Intelligence Companies in Switzerland - 28

About 4D Lifetec AG 4D Lifetec is a pioneer on a mission to revolutionize early cancer detection. Our easy and powerful blood tests can detect cancer at its earliest stages (I and II), offering you peace of mind and proactive well-being protection. Sophisticated artificial intelligence (AI) enhances our immunological high-throughput blood assays which in turn enables timely intervention and treatment.

The decoding of the proteome is revolutionizing the way diseases are diagnosed, treated, and prevented. Biognosys invents and provides patented proteomics solutions at the quality, scale, and speed required to transform R&D, clinical trials, and clinical decision making. Our Solutions We offer a versatile portfolio of proprietary proteomics services, software, and kits. We make these widely available for pharmaceutical and biotechnology researchers and proteomics experts. Our solutions provide a multi-dimensional view of protein expression, function, and structure in all major sample types – cells, tissues, or body fluids – across human and non-human species. Our Technology Biognosys is the leading inventor and developer of mass spectrometry-based proteomics solutions. With market leading proteome coverage and sample throughput we enable simultaneous quantification of thousands of proteins across thousands of samples. Our Facility From our global headquarters just outside of Zurich, we operate one of the largest high-end mass spectrometry laboratories worldwide for Large-Scale Discovery Proteomics contract research. Our Data Competence Biognosys has analyzed a vast amount of proteomics data and developed an industry-leading understanding of the proteome. Through advanced data analytics, Biognosys translates data into actionable insights for R&D and clinical research. Global Presence Founded in 2008 as a spin-off from the lab of proteomics pioneer Ruedi Aebersold at ETH Zurich, Biognosys today is an established leader in next-generation proteomics. With employees based across Switzerland, Europe, and US, and an extensive network of collaborators and distributors, Biognosys supports a global customer base of life science researchers across industry and academia.

At Bioscibex, we are redefining bioprocessing with innovative single-use bioreactor solutions tailored for modern biologics and cell therapy manufacturing. Our mission is to empower researchers and manufacturers with tools that simplify processes, enhance scalability, and improve efficiency.

Caris Life Sciences® (Caris) is the leading next-generation TechBio company and precision medicine pioneer that is actively developing and delivering innovative solutions to revolutionize healthcare and improve the human condition. Through comprehensive molecular profiling (Whole Exome and Whole Transcriptome Sequencing) and the application of advanced artificial intelligence (AI) and machine learning algorithms, Caris has created the large-scale, clinico-genomic database and computing capability needed to analyze and unravel the molecular complexity of disease. This convergence of sequencing power, big data and AI technologies provides an unmatched platform to deliver the next-generation of precision medicine tools for early detection, diagnosis, monitoring, therapy selection and drug development. Headquartered in Irving, Texas, Caris has offices in Phoenix, New York, Tokyo, Japan and Basel, Switzerland. Caris or its distributor partners provide services in the U.S., Europe, Asia and other international markets.

Cellestia Biotech is pioneering innovative therapeutics based on novel modes of action to treat autoimmune diseases and multi-drug resistant cancers. Our clinical stage drug candidate, CB-103, has demonstrated both safety and biological activity in humans. Along with ongoing Phase 2 IITs for multi-drug resistant cancers, CB-103 is also poised to enter a Proof-of-Concept clinical study for graft-versus-host disease (GvHD)

Our vision is to redefine the boundaries of neuroscience with minimally invasive technologies to enable unparalleled precision, enhance patient outcomes, and forge a new era of highly targeted neurotherapies for a healthier world.

Clinerion, a wholly owned subsidiary of TriNetX LLC, accelerates clinical research and medical access to treatments for patients. We use proprietary, patented technologies for analysis of live electronic health record (EHR) data from our global network of partner hospitals to generate real-world data (RWD), which can be used for investigation into disease epidemiology, the patient journey and outcomes, and patient care metrics. Clinerion's Patient Network Explorer platform radically improves the efficiency and effectiveness of clinical trials by offering data-driven protocol optimization, site feasibility evaluation, and search and identification for patient recruitment – in real-time. Among other uses, we provide solutions for increasing diversity in clinical trials and identification of rare disease patients. Clinerion's new Federated Machine Learning Platform enables the training and validation of machine learning (ML) algorithms on our global RWD network. Apart from the contributions to drug development this platform targets to develop preventive care for patients before they reach a critical stage. Clinerion operates on the principle of "privacy by design" and complies fully with international patient privacy and data security regulations. Clinerion is headquartered in Switzerland. Clinerion website: www.clinerion.com Clinerion's Patient Network Explorer: www.clinerion.com/index/OverviewOurSolutions/ClinerionPatientNetworkExplorer

Bridging the gap between disruptive discovery products and real-world patient reach, we identify high-potential compounds for in-licensing, we conduct clinical development and then select large pharmaceutical commercialization partners for out-licensing to maximize patient access across the globe. Through this specialized business model, Debiopharm can focus on the development of prescription drugs that target unmet medical needs in oncology and bacterial infections. Debiopharm completed the development and has licensed out 2 compounds: - Triptorelin, the active substance of Decapeptyl®/Trelstar®/Pamorelin®/Triptodur® 1, 3 and 6-month formulation and Moapar®/Salcacyl® -Oxaliplatin, the active substance of the branded Eloxatin®/Elplat®/Dacotin®/Dacplat® If your university or biotech start-up has interesting molecules in early-stage research and you’re seeking a competent and committed partner to develop them further, please contact us!

Engimmune is an immunotherapy company utilising cutting-edge methods for the development of T-cell receptor (TCR)-based immunotherapies including T cell therapies and biologics. By applying our unique protein engineering toolbox we have established and continue to develop proprietary high-throughput technology platforms enabling the discovery of highly potent and safe TCR-based cell therapies and biotherapeutics, thus covering the entire TCR discovery value chain. Operating as a platform technology and product development company, our vision is to become a globally leading provider of best-in-class TCR-based therapeutics for the treatment of serious human diseases with high unmet medical need, with a particular focus on oncology. Engimmune is based in a brand new science park in Allschwill, Basel in Switzerland

Founded in 1997, Genedata delivers enterprise solutions to enable Biopharma R&D globally to discover, develop, and manufacture innovative biotherapeutics faster and more efficiently. Genedata combines computational, scientific, and technical expertise with extensive biopharma R&D domain knowledge to deliver user-friendly solutions that are scalable, open, and aligned with industry processes. Today, most of the leading pharmaceutical, biotechnology, and agrichemical companies, as well as innovative life science research institutions rely on Genedata. Genedata is proud to be part of Danaher. Danaher’s science and technology leadership puts Genedata’s solutions at the forefront of the industry, so they can reach more people. Being part of Danaher means we can offer unparalleled breadth and depth of expertise and solutions to our customers. Together with Danaher’s other businesses across Biotechnology, Diagnostics and Life Sciences, we unlock the transformative potential of cutting-edge science and technology to improve billions of lives every day.

❌❓ THE CHALLENGE: Glycans hide the tumor in disguise. ➡ Typical cancer-specific Tumor Glycocodes render the tumor invisible to the immune system, they stay ‘cold’. Intelligently, glycans from that Tumor Glycocode are not present on neighbouring healthy tissue, rendering it a perfect target for eradication & potential use as biomarker for patient selection and treatment response. ➡ So far, efforts to break that code for therapeutic benefits have been unsuccessful. One reason for this is the dynamic shape & motion of glycans, and the inability to manufacture them ex vivo. ⭕❗ THE SOLUTION: Conjugated Glycopeptides. Gnubiotics’ proprietary technology conjugates O-glycans with short protein parts - peptides - ex vivo to form novel glycopeptides that are druggable targets amenable to mass production. 🔜 Breaking the Tumor Glycocode. Since 2019, multiple preclinical models have demonstrated proof of concept for the lead compound GNU101 to be orally bioavailable, resisting degradation, and surviving enzyme proteolysis. The preclinical body of evidence has demonstrated proof-of-concept that the GENESIS platform based glycopeptides are able to turn 'cold' into 'hot' tumors, breaking through I/O resistance and inducing tumor cell killing. 💡 THE TEAM: We are a highly specialized team of Founders, Scientists and Entrepreneurs pursuing the transition from a large basis of preclinical evidence into IND-readiness and the clinics with First-in-human clinical phase 1 study for colorectal cancer patients in 2024/2025. 📥 Curious to learn more? Check out our new website and contacts 🌐 https://gnubiotics.com/

Aktiia, now trading under Hilo, was established in 2018 to transform how blood pressure is measured and therefore managed. Hilo is transforming blood pressure monitoring with cuffless, AI-powered technology that delivers continuous, accessible insights for individuals and healthcare professionals. Our foundation model is trained on billions of optical signals and hundreds of millions of readings from over 120,000 users—one of the largest datasets in the field. Backed by a multidisciplinary team with deep expertise in biomedical signal processing, Hilo has contributed to over 120 peer-reviewed publications and holds more than 35 patents. Headquartered in Switzerland, we’re expanding globally to redefine how blood pressure is measured and managed.

InterAx Biotech integrates experimental and computational pharmacology to reveal critical properties of novel GPCR drug candidates. The company is specialized in GPCR drug discovery and covers hit-generation, hit-to-lead and lead optimization for all targets including orphan. InterAx Biotech is a Swiss drug discovery company that focuses on developing drugs targeting disease-specific GPCR heterodimers. The company is pioneering computational pharmacology for drug discovery and has entered into R&D agreements with other organizations for drug development. InterAx Biotech also announced the appointment of seasoned pharmaceutical executive, Mark Levick, MD, Ph.D., as a new board director.

We are a Swiss-based early-clinical stage biotech start-up. Using our breakthrough technology, ACINDA, we develop first-in-class, protein-protein interaction antagonists against invasive cancers.  Invasight's precise therapies will make a positive difference in the lives of patients with invasive cancers. 

InVirtuoLabs is a new-generation laboratory for drug discovery. We design novel drugs by combining advanced machine learning techniques with physics-based simulations to rapidly identify and optimize promising drug candidates.

Isospec Analytics is a life science company that aims at simplifying molecular identification. They provide high detection sensitivity suitable for bioanalytical applications and offer next-level molecular intelligence to empower biotechnology. Their technology takes the guesswork out of biomolecular analysis and they have raised $1.9m for their breakthrough biomolecular analysis technology.

Leman Biotech Co., Ltd. is a spin-off of EPFL co-founded by Prof. Li Tang (Head of Laboratory of Biomaterials for Immunoengineering). Leman Biotech aims at developing and commercializing new metabolic cancer immunotherapies. Recently, the start-up company closed a US$11 million angel financing round. The money raised will enable it to accelerate the preclinical studies of biomolecule and cell based therapies and prepare for entering clinical trials. The headquarter of the company is now in Shenzhen, a highly vibrant city with the highest number of start-ups per head of population in China. Currently, Leman Biotech is launching a new drug discovery center in Lausanne, Switzerland, to initiate clinical trials in Europe.

#Nanolive: Capture dynamic, unbiased live cell data to accelerate discovery, development and therapeutics. Nanolive delivers breakthrough 3D imaging solutions that accelerate research in growth industries such as drug discovery and cell therapy. Nanolive’s innovative solutions combine screening, imaging and analysis to radically advance how scientists study living cells and provide novel biological insights such as the mechanisms of cancer and neurodegenerative diseases.

Nerai Bio is a biotech startup pioneering ultra-specific genome editing technologies to treat genetic diseases. Using their AI-driven MORPHEME platform, they engineer novel gene-editing proteins that can precisely target and correct DNA at any location, addressing a broader range of genetic mutations than existing tools like CRISPR. Their lead therapeutic candidates focus on severe liver disorders, aiming to provide a single, permanent cure for conditions currently treated with lifelong care. Recently, Nerai Bio secured CHF 150,000 from Venture Kick to advance business development, preclinical validation studies, and partnerships.

Novigenix is a Swiss precision medicine company specialized in ImmunoTranscriptomic solutions for early detection of disease, development of novel therapeutics, and drug target discovery. The Novigenix proprietary LITOSeek™ platform is an AI-enabled RNA analytic platform optimized for mapping the response of the immune system to onset and progression of disease. Our analytical pipelines integrate patient multi-omics data with advanced Machine Learning and artificial intelligence approaches to provide actionable insights and precision solutions. Our liquid biopsy products and services include a suite of biopharma solutions for clinical development of novel therapies, drug target discovery, and early detection of Colorectal Cancer. Novigenix provides services to Pharma and Biotech customers by leveraging the proprietary LITOSeek™ data analytics and patient clinical data platform to deliver previously unknown insights into heterogeneity of patient response and development of actionable biomarkers for optimization of new therapeutic modalities. Specialties Precision Medicine solutions in oncology and immunology, ImmunoTranscriptomics, Machine Learning and Artificial Intelligence, clinical development of multi-omics biomarkers, standardized RNAseq platform and analytic pipelines, product development for In-vitro Diagnostics and Liquid Biopsy solutions.

Oncobit is a medtech UZH Spin-off, enabling personalized cancer care by matching patients to the best cancer treatment available. We are developing cancer-specific genomic fingerprinting and personalized monitoring tests and provide therapy decision support.

Onena Medicines is a biopharmaceutical company with a pipeline of first-in-class antibody medicines to treat recurrent and metastatic cancers and selected rare diseases. Onena’s drugs neutralize a new class of secreted ancient growth factors, conserved across species, called Dual SMAD Inhibiting Proteins (DSIPs), that program cancer cells to grow and resist chemotherapy. Blocking DSIPs, as demonstrated in-vivo by Onena, simultaneously reactivates physiological TGF-β and BMP signaling and elicits cellular reprogramming, resulting in cancer cells accepting environmental cell death signals from BMPs and Activins. Onena has developed a proprietary AI-centric antibody drug discovery platform that rapidly generates anti-DSIP neutralizing antibodies, even when no crystal structure of the antigen is available. OMED-101, Onena’s anti-LEFTY1/2 lead candidate antibody, has demonstrated broad efficacy against breast, colorectal and brain cancers without observable toxicities in preclinical models. Through its unique platform, Onena Medicines has discovered several DSIPs and aims to advance multiple neutralizing DSIP antibody drugs into clinical development in the next three years.

Orbis Medicines, a leader in oral macrocycle drug discovery, today announces its launch with a €26 million financing led by global life sciences investor Novo. The company is focused on macrocycle drugs, described as a family of compounds with a platform to discover, develop.

PreCombTherapeutics AG is a privately held Swiss biotechcompany focused on in vitro cancer diagnostic to improve cancer management. It's automated microtumor-based 3DTwin™ technology enables clinical institutions to integrate the technology on-site in the hospital. The test makes it possible to functionally evaluate multiple cancer drugs, drug combinations and drug concentrations directly on patient-derived micro-tumors to maximize treatment outcome.

True precision medicine through single-cell science. Scailyte, a pioneer in AI-driven biomarker discovery from single-cell omics data, has leveraged its proprietary AI platform, ScaiVision, to analyze over 60 million single-cell profiles. The company's extensive network of clinical partners and access to unique patient cohorts in oncology and auto-immunity have led to the development of multiple patent-pending biomarker signatures. Headquartered in Basel, Switzerland, Scailyte collaborates with clinical-stage biotech and pharma companies worldwide, enabling biomarker-driven drug development and paving the way for precision medicine to become a reality. If you want to partner with, reach out to contact@scailyte.com More information about our company, technology & services you can find on our website - https://scailyte.com

Our combined excellence in software development within the field of analytics allows us to drive real advancements in data management. We provide and develop high-quality and innovative vendor-agnostic software solutions that are highly compatible without compromising performance. By automating and digitalizing workflows for generating, analyzing, and utilizing scientific data, we help our customers achieve scientific results faster and more conveniently, enabling better and quicker decision-making.

SOPHiA GENETICS is a healthcare company that specializes in genomics analysis using artificial intelligence and data analysis.

STALICLA SA is a Swiss clinical-stage biopharmaceutical company pioneering Neuro Precision Medicine in neurodevelopmental and neuropsychiatric disorders. With state-of-the-art technology platforms and clinical trials for Autism Spectrum Disorder (ASD) and Substance Use Disorder (SUD), STALICLA is changing the landscape of brain disease treatments. Neurodevelopmental Disorders: To propel neurodevelopmental research, STALICLA have identified patient subgroups and their matching candidate drugs within Autism Spectrum Disorder using its trailblazing, multi-omics DEPI platform. STALICLA is currently preparing Phase 2 trials for STP1, STALICLA's first patient subgroup-matched precision treatment. Substance Use Disorder research: STALICLA is working in partnership with the National Institute of Drug Abuse (NIDA) to advance Phase 3 clinical trials for the most clinically advanced drug candidate for cocaine abuse disorder, STP7. STALICLA is now raising series C funding to advance both verticals. For more information visit: https://stalicla.com.