Vivlion's proprietary PRCISR™ CRISPR technology represents a significant advancement in CRISPR screening methodologies. This platform enables the generation of gRNA libraries without the traditional challenges associated with PCR amplification and cloning techniques, which often lead to uneven distribution and bias in gene representation. By utilizing a covalently-closed-circular-synthesized (3Cs) approach, Vivlion ensures that their libraries maintain exceptional uniformity, allowing for a more accurate identification of gene targets. The technology supports unlimited diversity in library creation, offering both single and dual-combinatorial gRNA formats, which enhances the potential for comprehensive genetic exploration and interaction testing.

The benefits of Vivlion's PRCISR™ CRISPR libraries extend to maximizing experimental efficiency and minimizing resource requirements. These libraries can significantly downscale experimental sizes, reducing the need for extensive cell culture materials while still achieving high gene editing efficiencies of over 90%. Additionally, Vivlion provides tailored services that encompass experimental design, library production, and bioinformatics analysis, ensuring that clients receive comprehensive support throughout their CRISPR screening projects. This integrated approach not only streamlines the research process but also enhances the reliability and quality of the resulting data, making Vivlion a valuable partner in the field of genetic research and therapeutic development.

Germany

We provide innovative gene editing reagents, screening services and engineered model systems for the global R&D market. Our success is based on the proprietary 3Cs technology.

Vivlion

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