GangaGen is focused on developing innovative treatments for drug-resistant bacterial infections, particularly through the use of protein antibacterials derived from bacteriophages. Their primary product, the chimeric protein P128, has shown significant efficacy against various strains of drug-resistant Staphylococcus aureus. Research indicates that P128 can effectively restore sensitivity in these resistant strains, demonstrating its potential as a powerful therapeutic agent. The company’s pipeline includes multiple studies that highlight the ability of P128 to kill both planktonic and biofilm-embedded bacteria, which are often more challenging to treat due to their protective biofilm structures.

The scientific foundation of GangaGen's approach is supported by numerous research publications that detail the mechanisms of action of bacteriophage-derived lysins, such as P128. These studies illustrate how P128 cleaves the peptidoglycan layer of bacterial cells, leading to their destruction. Additionally, the research emphasizes the synergistic effects of combining P128 with traditional antibiotics to enhance their efficacy against biofilms. GangaGen's commitment to addressing the growing challenge of antibiotic resistance positions it at the forefront of developing novel antibacterial therapies that leverage the unique properties of bacteriophage-derived proteins.

India

GangaGen Biotechnologies Private Limited, India (GBPL), is a biologics company specialized in discovering, designing and developing novel treatments for drug-resistant bacterial infections. The company is focused on developing products for the prevention and treatment of bacterial infections, including pneumonia caused by multidrug-resistant bacteria. GangaGen is a clinical-stage biotechnology company with a focus on developing novel therapeutic proteins.

Infectious Diseases

Gangagen

Staph aureus

Anti-Staphylococcal Protein Antibiotic P128

Biologics

Gangagen Biotechnologies Pvt. Ltd., 2nd Floor, No. 36, 1st Main, 1st Cross, Mico Layout, BTM 2nd Stage, Bangalore - 560076, Karnataka, India

Gangagen

Company Details