Cell therapy for autoimmune and neurodegenerative diseases

Altucell is a biotech therapeutic company focused on developing innovative treatments for various chronic and autoimmune diseases, including diabetes, neurodegenerative disorders, and fatty liver disease. The company employs advanced encapsulated cell therapy, which utilizes patented engineered cells combined with a unique encapsulation technology. This approach allows for the therapeutic potential of cells to be harnessed without the need for immunosuppression, making it a promising avenue for treating serious conditions. The engineered cells are designed to express high levels of immuno-regulatory proteins, survive in encapsulated environments, and undergo controlled division, enabling large-scale production and application across multiple diseases.

One of Altucell's key technologies involves Sertoli cell transplantation, which has shown significant promise in protecting islet cells from immune destruction in Type 1 Diabetes models. By encapsulating Sertoli cells in barium alginate-based microcapsules, Altucell aims to provide immune protection and promote beta-cell regeneration. Additionally, the company has developed ALTUSTEM, a stem cell-derived myofibroblast from Wharton’s jelly, which is formulated to preserve beta cells and potentially reduce insulin dependency. Their proprietary delivery system, ALTUCAP, further enhances the immune-protective capabilities of the transplanted cells, ensuring compliance with regulatory standards while addressing critical challenges in cell therapy.

United States

Altucell, Inc. is a cellular engineering and biotech company backed by sound research and science focused on fulfilling a large "unmet need" in cell, molecular and regenerative therapy for treatment of Diabetes and other autoimmune and neurodegenerative diseases. The company’s proprietary and unique technology overcomes the major barriers to transplantation by a novel strategy utilizing patented micro-encapsulation technology, enabling a transplantable, cell-based therapy that avoids detection and rejection by the immune system.

Altucell

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