TREOS BIO LIMITED is pioneering advancements in cancer immunotherapy through its innovative approach to personalized medicine. The company focuses on developing personalized peptide cancer immunotherapies that are tailored to match patients' genetic profiles. By utilizing proprietary therapeutic peptides, TREOS can stimulate effective immune responses in patients predicted to benefit from these treatments based on their genetic makeup. This is facilitated by their predictive diagnostic tests, which identify "personal epitopes" (PEPIs) that bind to multiple HLA alleles, allowing for a more accurate prediction of T cell responses. This novel understanding of HLA genetics and immune response variability is central to TREOS's strategy, enabling the design of immunotherapies that are both effective and broadly applicable.

In addition to personalized therapies, TREOS is also developing off-the-shelf peptide cancer vaccines that do not require pre-screening for specific HLA alleles, thus increasing accessibility for a wider patient population. Their digital immunotherapy development leverages a comprehensive knowledgebase that connects HLA genetics with tumor antigen expression, allowing for the creation of vaccines that can be tailored using simple blood or saliva samples instead of invasive tumor biopsies. This approach not only streamlines the treatment process but also aims to deliver faster, better, and more cost-effective personalized immunotherapies, ultimately transforming the landscape of cancer treatment.

United Kingdom

Treos Bio is a clinical stage company introducing a disruptive computational technology to change the paradigm of cancer immunotherapy development by resolving the dual challenges of patient and tumor heterogeneity. We use proprietary therapeutic peptides, produced through commercially scalable processes without need for tumor biopsy, to stimulate clinically effective cancer-specific immune responses in patients predicted by our diagnostic tests to respond.

TREOS BIO LIMITED

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