Rational Vaccines is an investigational-stage company dedicated to addressing the global health challenges posed by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2). The company is pioneering the development of live attenuated viral vaccines, which are designed to elicit a robust immune response while minimizing the risk of disease. Their approach is grounded in the research of Dr. William Halford, who emphasized the potential of properly attenuated live viral vaccines to provide long-lasting protection against infectious diseases. By utilizing rational design principles, Rational Vaccines aims to create vaccine candidates that can effectively stimulate the immune system, thereby reducing the transmission and impact of herpes infections.

The proprietary technology developed by Rational Vaccines focuses on specific mutations in the infected cell protein 0 (ICP0) gene of the herpes virus. These mutations are intended to weaken the virus's ability to cause disease while maintaining its capacity to provoke a strong immune response. This innovative strategy seeks to transform the treatment and prevention landscape for herpes-related diseases, offering hope for improved patient outcomes and a potential pathway toward a future free of herpes. The company is currently advancing multiple vaccine candidates through pre-clinical stages, with the goal of revolutionizing the management of herpes infections globally.

United States

Rational Vaccines is a preclinical stage herpes vaccine development company actively working to improves lives with the hope of revolutionizing the treatment, prevention and diagnosis of herpes and herpes-related diseases worldwide.

Rational Vaccines

Company Details