Small Molecules approved in Europe, trying to bring the US

ANeuroTech is focused on addressing the significant unmet medical need for effective treatments for Partial Responsive Depression (PRD). The company is advancing its late-stage Phase III drug, ANT01, which is an orally administered small molecule designed to enhance the effects of initial antidepressant therapies while specifically targeting subjective cognitive decline. ANT01 operates as a highly selective blocker of the serotonin 2A and dopamine 4 receptors in the brain, which distinguishes it from existing treatments that often come with considerable side effects, such as motor issues and metabolic syndrome. This innovative approach aims to improve emotional and cognitive functions in patients who do not adequately respond to traditional antidepressants.

The market potential for ANT01 is substantial, with estimates suggesting that around 3 million patients in the U.S. are diagnosed with PRD annually after initial antidepressant treatment. Given the limitations of current adjunctive treatments, ANT01 presents a promising alternative that could significantly enhance patient adherence and treatment durability. The company anticipates that with a competitive pricing strategy and a focus on a larger patient population, ANT01 could achieve peak annual sales ranging from $1.5 billion to as high as $6 billion, depending on treatment duration and market penetration. This positions ANeuroTech as a key player in the evolving landscape of depression treatment, leveraging its deep expertise in neuroscience and drug development.

Belgium

ANEUROTECH is developing its late stage Phase III drug ANT01 in Partial Responsive Depression (PRD). ANT01 is an once daily, orally-administered small molecule to attack Subjective Cognitive Decline and Potentiate Initial Antidepressant Therapies.

ANeuroTech

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