Repligen Corporation specializes in advanced bioprocessing technologies aimed at enhancing the production of biologic drugs. Their innovative offerings include the KrosFlo® series of Tangential Flow Filtration (TFF) systems, which are designed for both bench-scale and large-scale applications. The KrosFlo® RS 10 is notable for being the first bench-scale TFF system built specifically for current Good Manufacturing Practice (cGMP) production, featuring true end-to-end automation. Additionally, the TangenX® SC device represents a significant advancement as the first holder-free, self-contained TFF device, ideal for closed-system manufacturing of biologics. Repligen's acquisition of Metenova and FlexBiosys further strengthens their Fluid Management franchise, enhancing their portfolio of single-use mixing solutions and bioprocessing bags.

In the realm of process analytics, Repligen has introduced the CTech™ FlowVPX® system, which utilizes Variable Pathlength Technology (VPT) for accurate protein concentration measurement. This technology allows for real-time monitoring of protein concentrations during biomanufacturing, addressing challenges associated with traditional spectrophotometers that struggle with high concentrations. The FlowVPX system provides continuous readings and eliminates the need for sample dilution, thereby improving efficiency and accuracy in the production of biologics. Repligen's commitment to innovation is evident in their focus on scalable solutions that support the evolving needs of the biopharmaceutical industry, including the development of new modalities such as plasmid DNA and viral vectors.

United States

Repligen is a bioprocessing-focused life sciences company bringing over 40 years of expertise and innovation to our customers. We are inspiring advances in bioprocessing through the development and commercialization of high-value products and flexible solutions that address critical steps in the production of biologic drugs, principally monoclonal antibodies.

Repligen Corporation

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