TRex Bio is pioneering a unique approach to drug discovery and development through its Deep Biology Platform, which focuses on human tissue biology to understand and address immune-mediated diseases. This platform enables the mapping of regulatory T cell (T reg) behavior within human tissues, allowing for the identification of novel therapeutic targets that can restore tissue homeostasis and mitigate inflammation. By utilizing a robust collection of human tissue samples from both healthy and diseased states, TRex Bio employs advanced sequencing technologies and computational tools to generate high-resolution insights into the immune regulation processes that underlie various diseases.

The company emphasizes the importance of T regs, a specialized subset of T cells that play a crucial role in regulating immune responses and tissue inflammation. TRex Bio's innovative approach combines modern computational biology with functional genomics to create a comprehensive understanding of T reg modulation and its implications for therapeutic development. Their methodologies include bulk and single-cell RNA sequencing, the creation of a T reg Atlas for in vitro validation, and a suite of functional assays designed to explore the biology of T regs in health and disease. This multidisciplinary strategy positions TRex Bio at the forefront of developing next-generation therapeutics aimed at treating autoimmune and inflammatory conditions.

United States

TRexBio is a discovery stage biotechnology company leveraging cutting edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for cancer and inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue Treg behavior to disease processes, allowing us to identify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis. TRexBio is headquartered in South San Francisco, California.

TRex Bio

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