Yaqrit is at the forefront of developing innovative treatments for liver diseases, particularly focusing on conditions such as Acute-on-Chronic Liver Failure (ACLF). One of their key technologies is the DIALIVE (YAQ002), an extracorporeal liver support device designed to remove harmful toxins from the blood of patients suffering from advanced liver disease. This device has shown promise in earlier studies, demonstrating its safety and efficacy in resolving liver failure. The company has recently secured a significant clinical research grant from the National Institute for Health and Care Research (NIHR) to support registrational trials for DIALIVE, which will take place across multiple clinical centers in the UK.

In addition to DIALIVE, Yaqrit is advancing another promising therapeutic candidate, YAQ005, a toll-like receptor 4 antagonist licensed from University College London. This drug aims to address the toxic buildup of ammonia in liver disease patients, which can lead to severe complications, including brain dysfunction. The research has established a critical link between ammonia accumulation and liver cell death, highlighting the potential of YAQ005 to halt this detrimental process. Yaqrit's commitment to addressing the unmet medical needs of patients with liver diseases is further underscored by their strategic partnerships and ongoing clinical trials, positioning them as a significant player in the biotechnology sector focused on liver health.

United Kingdom

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Yaqrit

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