Novelty Nobility Inc. focuses on innovative therapeutic solutions, particularly in the fields of oncology and ophthalmology, leveraging advanced antibody technologies. One of their key products, NN2802, is a fully human IgG1 monoclonal antibody that targets c-Kit, a receptor involved in mast cell activation and related diseases. This antibody has shown promising results in preclinical studies, demonstrating a rapid pharmacodynamic response by inhibiting tryptase, a biomarker associated with mast cell-driven conditions. The company is also developing NN3201, an antibody-drug conjugate (ADC) that combines a c-Kit targeting antibody with a cytotoxic payload, designed to treat various cancers, including small cell lung cancer and gastrointestinal stromal tumors. This ADC aims to overcome drug resistance by utilizing a proprietary linker technology that enhances the therapeutic index.

In addition to their oncology-focused products, Novelty Nobility is advancing research in ocular diseases through their bispecific antibodies, such as NN4101, which targets both c-Kit and VEGF to address neovascular retinal diseases. This approach aims to modulate the hypoxic environment that contributes to retinal pathologies by regulating angiogenic factors and improving treatment durability. The company’s research highlights the significance of the SCF/c-Kit signaling pathway in both cancer and ocular conditions, positioning it as a novel target for therapeutic intervention. Overall, Novelty Nobility Inc. is at the forefront of developing targeted therapies that address unmet medical needs in complex diseases through innovative antibody-based technologies.

South Korea

Novelty Nobility Inc. is a private clinical stage biotech company located in Pangyo, South Korea, and Boston, Massachusetts. We are currently focused on the research of novel angiogenesis targets and develop antibody-based therapeutics in ophthalmology and oncology, where angiogenesis plays a key pathogenic role.

Novelty Nobility, a unique name for a biotech company, stands for what we pursue – Novel Science, Noble Management. The emblem in the middle of our logo, which shapes a drug, symbolizes our belief that a new drug is born when novel science meets noble management.

Novelty Nobility Inc.

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