Immunotherapy Drug Discovery Platform, AbLecs

Valora Therapeutics is pioneering a transformative approach to immunotherapy through its proprietary AbLec™ platform, which focuses on the intricate field of glycobiology. This innovative technology aims to restore effective immune communication by decoding the complex sugar code that governs interactions between cells and the immune system. The AbLec™ platform specifically targets glyco-immune checkpoints, which are critical control points in the immune response that have been largely overlooked in therapeutic development. By utilizing engineered antibodies that combine both antibody and lectin domains, Valora's AbLec™ constructs can precisely modulate immune responses, enhancing or suppressing them as needed, while minimizing off-target effects.

The AbLec™ platform holds significant promise for treating a variety of diseases, particularly cancer and autoimmune disorders. In cancer immunotherapy, the technology is designed to block inhibitory signals that tumors exploit to evade immune detection, thereby reactivating anti-tumor responses. For autoimmune diseases, AbLec™ aims to restore immune balance by precisely modulating specific immune cell subsets, potentially leading to targeted therapies with fewer side effects compared to traditional immunosuppressants. Overall, Valora Therapeutics is committed to advancing the understanding of glyco-immune modulation, translating complex glycobiology into effective therapies that could significantly improve patient outcomes across multiple therapeutic areas.

United States

Valora Therapeutics Inc. (Valora) is a pre-clinical stage biopharmaceutical company based in San Diego, California, USA, pioneering a new biologic platform invented by Nobel Laureate Dr. Carolyn Bertozzi (Stanford). Our proprietary platform technology enables the engineering of chimeric antibodies to unlock new mechanisms of immune signaling and activity, paving the way for transformative therapies in oncology, immune diseases, and beyond. 

Valora Therapeutics

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