Cell Line Genetics specializes in the assessment and authentication of cell lines, utilizing advanced technologies such as Fluorescence in-situ hybridization (FISH). This technique is particularly effective for detecting small populations of interphase cells with clonal aberrations, allowing researchers to identify and monitor genetic integrity over time. FISH probes can be employed to screen large numbers of cultures for recurrent chromosome aberrations, providing a high degree of sensitivity that surpasses standard cytogenetic methods. This capability is crucial for ensuring the reliability of cell lines used in research, especially when dealing with stem cells.

Among their product offerings, Cell Line Genetics provides the Human StemCheck™ FISH probes, which are designed to quickly assess the occurrence of trisomy in cultured stem cell lines. These probes specifically target the four most common trisomies that may arise during the culturing of embryonic stem cells (ESC) and induced pluripotent stem cell (iPSC) lines. Additionally, the company offers gene-specific FISH probes for rapid determination of gene copy number and the option for custom FISH probes, catering to specific research needs. This comprehensive suite of tools supports researchers in maintaining the genetic integrity of their cell lines, ultimately advancing their scientific endeavors.

United States

Cell Line Genetics, Inc,(CLG) is the leading independent  provider of multi-species Quality Assurance services and products for the Regenerative Medicine market.  

Headquartered in Madison, Wisconsin and with offices in New York City, CLG's clients include leading universities and research institutes, as well as biotechnology and pharmaceutical companies.  

For a complete list of CLG products and services please visit www.clgenetics.com.

Cell Line Genetics

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