APTAGEN Labs specializes in synthetic biology, focusing on the development of DNA-based antibodies known as aptamers. With over 30 years of experience, the company has established itself as a global leader in this field. Aptamers serve as highly specific and high-affinity target-recognition elements that can bind to a variety of targets, including small molecules, protein biomarkers, cells, and tissues. They offer a versatile alternative to traditional antibodies for applications in diagnostics, therapeutics, and bio-industrial processes. APTAGEN Labs has developed innovative diagnostic platforms, such as the Apta-Beacon assay, which streamlines the detection process by eliminating multiple manipulation steps typically required in conventional diagnostic methods.

In addition to aptamers, APTAGEN Labs has introduced the concept of "aptabodies," which are advanced supramolecular forms of aptamers designed to enhance functionality through the incorporation of various functional groups. This innovation aims to improve molecular targeting, cellular trafficking, and pharmacokinetics, making aptabodies a promising candidate for therapeutic applications. The company also emphasizes a rapid approach to drug discovery, utilizing aptamers and aptabodies to bypass traditional in vitro testing, thereby reducing development time and costs. This methodology allows for the selection of drug candidates directly in whole animal models, streamlining the path to human clinical trials and potentially revolutionizing the pharmaceutical development landscape.

United States

APTAGEN Labs is a biotechnology company offering aptamer and aptabody custom-based services to replace antibodies in research, diagnostic platforms, drug discovery and therapeutics.

Aptagen was formed in 2004. Operations began in 2006.  Aptagen is located in Jacobus, PA, a suburb of York, beautifully surrounded by Lake Redman and conveniently situated off of Interstate 83. The facility is a forty minute drive from Johns Hopkins University and Hershey Medical Center.

APTAGEN Labs

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