Jumpcode Genomics focuses on enhancing the utility of next-generation sequencing (NGS) data through innovative technologies designed to deplete unwanted fragments from NGS libraries. Their flagship products, DepleteX™ and CRISPRclean®, utilize advanced CRISPR-Cas9 mediated techniques to selectively remove overabundant ribosomal RNA and other undesired sequences. This targeted depletion significantly improves the sensitivity and accuracy of genomic analyses across various applications, including single-cell analysis, microbiome characterization, infectious disease detection, and whole transcriptome profiling. By reducing background noise and enhancing the representation of biologically relevant transcripts, these technologies enable researchers to gain deeper insights into gene expression patterns and microbial populations.

The CRISPRclean Stranded Total RNA Prep with rRNA Depletion is particularly noteworthy for its efficiency and specificity. It allows for the preparation of RNA sequencing libraries with over 90% depletion of ribosomal RNA, ensuring high-quality representation of transcripts. The one-day workflow is designed for multiple species, including human, mouse, and rat, and it maintains high strand specificity and low library bias. This technology not only facilitates the detection of lower-expressing transcripts but also provides consistent and uniform coverage across transcript lengths, making it a valuable tool for researchers aiming to accurately measure gene expression and explore complex genomic landscapes.

United States

Jumpcode Genomics is changing the way scientists see their samples with our proprietary CRISPRclean® technology. Combining CRISPR-based technology and next-generation sequencing (NGS) they can now search for and find novel signals they previously couldn't. Our technology removes unwanted sequences, allowing researchers worldwide to extract greater insights. By increasing sensitivity and allowing access to a range of sample types, we're broadening the understanding of human biology in fields from research to clinical applications including infectious disease and oncology.

Jumpcode Genomics

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