Identifying genetic reasons for drug response

Predictive Biology employs a range of advanced technologies to explore the genetic underpinnings of complex traits and drug responses. Their research integrates in vitro genetics, stem cell biology, organoids, and single-cell technologies to investigate the molecular mechanisms associated with various diseases, including psychiatric disorders and environmental toxicology. By utilizing their in vitro genetics platform, they aim to identify novel drug targets and elucidate the mechanisms of drug action, particularly in genetically diverse backgrounds. This approach allows for a more comprehensive understanding of drug efficacy and safety, which is crucial for improving preclinical studies and ultimately enhancing drug discovery processes.

The company also focuses on environmental toxicology, recognizing the significant role genetics plays in susceptibility to toxicants. Their research aims to identify genetic factors that modulate toxic responses, which can inform the development of predictive toxicity assays and improve public safety measures. Current projects include using cerebral organoids to study developmental neurotoxicants and developing advanced assays for genetic screening. Predictive Biology's innovative methodologies, such as high-throughput screening and custom assay development, enable them to conduct extensive analyses of cellular responses, thereby advancing the understanding of both drug action and environmental health risks.

United States

Predictive Biologybrings together stem cell biology, high throughput screening and genetics to elucidate molecular mechanisms underlying compound response.

Predictive Biology

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