Customized AAV vector cloning/packaging services

PackGene Biotech Inc. specializes in advanced gene therapy technologies, particularly focusing on adeno-associated virus (AAV) and lentivirus vector systems. Their proprietary π-Alpha 293 AAV High-yield Production Platform significantly enhances AAV production efficiency, achieving yields that are 3 to 8 times higher than traditional methods. This platform utilizes a unique triple-plasmid transfection system and incorporates quality-by-design (QbD) optimizations throughout the production process, allowing for scalable production of AAV suitable for clinical and commercial applications. PackGene's commitment to quality is evident in their rigorous quality control measures, which ensure low levels of impurities and high purity of the viral vectors produced.

In addition to AAV production, PackGene offers a comprehensive suite of services, including custom AAV packaging, lentivirus services, and mRNA services. Their capabilities extend to GMP manufacturing, ensuring that products meet the stringent requirements for clinical use. The company also provides off-the-shelf mRNA and lipid nanoparticle (LNP) formulations, facilitating rapid research and development processes. With a focus on innovation and customer satisfaction, PackGene has established itself as a leading contract research organization (CRO) and contract development and manufacturing organization (CDMO) in the biotechnology sector, supporting a wide range of gene and cell therapy applications.

United States

PackGene is a world-leading AAV vector packaging CRO and CDMO. Founded in Massachusetts, USA, PackGene now has offices in Boston, Houston and Zurich. We work with customers to support gene therapy programs from early-stage R&D, preclinical development, to IND studies. Our mission is to accelerate gene therapy product development by providing an integrated one-stop solution including plasmid, viral vector, fill-finish and QC analytical services for the gene therapy industry.

PackGene Biotech INC

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