Navidea Biopharmaceuticals is at the forefront of precision medicine, focusing on the development of immuno-targeted products that enhance the identification and treatment of diseases, particularly cancer and autoimmune conditions. Central to their approach is the Manocept™ technology, which enables the creation of next-generation diagnostics and therapies. This technology leverages the targeting of CD206, a receptor found on certain immune cells, to improve diagnostic accuracy and facilitate targeted treatment strategies. By utilizing radiopharmaceuticals, Navidea aims to provide better clinical decision-making tools that ultimately enhance patient care.

The company has developed several innovative products, including 99mTc-tilmanocept, which is designed for various applications such as identifying rheumatoid arthritis-driving macrophages, targeting Kaposi sarcoma lesions, and improving cardiovascular disease diagnostics. Their proprietary imaging agent, Lymphoseek®, is particularly noteworthy for its high specificity in lymphatic mapping, aiding in the surgical treatment of cancers by accurately identifying sentinel lymph nodes. Additionally, Navidea is exploring the use of imaging agents like [18F]NAV4694 for early detection of Alzheimer's disease, showcasing their commitment to advancing diagnostic capabilities across a range of medical conditions.

United States

Navidea Biopharmaceuticals, Inc. (NYSE: NAVB) is a leader in precision medicine with immuno-targeted products designed to help identify the sites and pathways of undetected disease and enable better diagnostic accuracy, clinical decision-making, targeted treatment and, ultimately, patient care. Applying our Manocept™ technology, Navidea seeks to develop next-generation targeted diagnostics and therapies for cancer, autoimmune conditions, and other inflammatory diseases, with an initial focus on personalized Rheumatoid Arthritis diagnostics. The company, founded in 1983, maintains headquarters in Dublin, Ohio.

Navidea Biopharmaceuticals

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