Boston Bioprocess specializes in providing comprehensive solutions for process development and optimization tailored for biotech companies. Their services encompass a full suite of fermentation and downstream processing capabilities, ranging from benchtop to pilot scale. The company focuses on fermentation optimization to enhance yield, strain testing under commercial manufacturing conditions, and media and process optimization. They also emphasize GRAS (Generally Recognized As Safe) oriented process development and downstream processing to minimize product loss. Their expertise extends to protein purification through multi-stage tangential flow filtration (TFF) and spray drying, alongside regulatory guidance to navigate the FDA approval process effectively.

In addition to their core services, Boston Bioprocess offers robust capabilities in aerobic fermentation across various microorganisms, including yeast, bacteria, and filamentous fungi, utilizing vessels that range from 1.5L to 1,500L for stepwise scale-up. Their product separation techniques involve solid/liquid and liquid/liquid separations, employing centrifuges, homogenizers, and chemical lysis methods. The company also boasts a well-equipped analytical lab that supports their operations with advanced techniques such as HPLC, GC, and mass spectrometry. Through partnerships with institutions like the Integrated Bioprocessing Research Laboratory (IBRL), Boston Bioprocess is positioned as a key player in advancing biomanufacturing and bioprocessing technologies, facilitating the transition from laboratory-scale processes to industrial-scale production.

United States

Boston Bioprocess helps biotech companies develop, scale up and optimize fermentation and DSP processes. We aim to remove knowledge and capacity bottlenecks in the transition from lab to commercial manufacturing.

Boston Bioprocess

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