Ion channel drug discovery services, cardiac safety screening and translational neuroscience assays

Metrion Biosciences specializes in preclinical drug discovery services, focusing on ion channel screening, cardiac safety, and neuroscience. Their ion channel screening services include high-throughput screening and the use of compound libraries to evaluate the effects of various compounds on ion channels. In the realm of cardiac safety, Metrion offers both GLP and non-GLP hERG testing, as well as a clinically translatable assay using hiPSC-derived cardiomyocytes through their VOLTA platform. This platform is designed for early cardiac derisking and includes assessments for chronic cardiotoxicity and CiPA screening, ensuring that potential cardiac risks are identified early in the drug development process.

In addition to their ion channel and cardiac safety services, Metrion provides neuroscience services aimed at CNS drug discovery. This includes the use of brain slice tissue and assessments of native neuronal ion channels, as well as evaluations of central and peripheral neuronal firing. Their integrated drug discovery approach combines these various services to deliver comprehensive support for pharmaceutical research and development. Metrion's commitment to high-quality data and customer service positions them as a leader in the contract research organization (CRO) space, empowering their clients in the pharmaceutical industry to achieve successful outcomes in drug development.

United Kingdom

Metrion Biosciences is a specialist preclinical drug discovery CRO - your trusted partner for ion channel screening, cardiac safety screening and neuroscience assays.

We  provide our customers with a range of in vitro screening services, including cardiac safety (GLP hERG, CiPA panel of human cardiac ion channels) and neurotoxicology testing and phenotypic assays on a fee-for-service or collaboration basis.

We pride ourselves on being able to provide a flexible and cost effective service with an unparalleled level of expertise. Collectively, we have 250 years experience managing ion channel research programmes.

Metrion Biosciences

Company Details