Cell Guidance Systems specializes in advanced growth factor technologies, particularly through their proprietary PODS® (Protein-Optimized Depot Systems) technology. Unlike conventional growth factors that degrade quickly and require frequent replenishment, PODS® are designed to provide a sustained release of bioactive proteins over an extended period, typically 4 to 8 weeks. This is achieved by encapsulating the growth factors within a microcrystalline protein lattice that protects them from degradation and allows for a controlled release via proteolytic activity from surrounding cells. The result is a more stable and consistent concentration of growth factors in cell culture, which can significantly enhance cellular function and health, particularly in sensitive cell types like neurons.

In addition to PODS®, Cell Guidance Systems offers a range of innovative products including PeptiGel, a self-assembling peptide hydrogel, and Exo-spin™, a rapid exosome purification system. PeptiGel provides a reliable and tunable environment for cell culture, while Exo-spin™ allows for the efficient purification of exosome samples in just 30 minutes. The company emphasizes the importance of formulation in optimizing the performance of growth factors and other biological materials, ensuring that researchers can achieve better results in both in vitro and in vivo applications. Overall, Cell Guidance Systems is at the forefront of developing technologies that enhance the utility and effectiveness of growth factors in research and therapeutic contexts.

United Kingdom

Manchester Biogel PeptiGel products are now part of Cell Guidance Systems.

PeptiGel technology allows us to offer a family of high-quality peptide hydrogels, with a range of mechanical and functional properties, to enable you to find the most suitable materials for your application needs.  PeptiGel hydrogels mimic the cell micro-environment and provide a natural physiological extracellular matrix that open up exciting new opportunities within the fields of 3D cell-culture, 3D bioprinting, regenerative medicine and medical devices to solve current healthcare challenges. Our technical support is available to help you realise your research ambition.

Cell Guidance Systems

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