Elypta is at the forefront of cancer detection technology, focusing on a metabolism-based liquid biopsy approach. Their flagship product, the Elypta MIRAM® Kit, is designed to measure the GAGome, which consists of system biomarkers related to tumor metabolism. By employing machine learning techniques, Elypta aims to identify cancer signatures noninvasively through a simple urine test. Recent studies have shown that urine glycosaminoglycan profiles can predict the risk of developing various types of cancer up to six years prior to diagnosis, highlighting the potential of their technology in early cancer detection.

The company utilizes advanced systems biology to uncover biomarkers associated with cancer metabolism, particularly through the analysis of glycosaminoglycans (GAGs). The MIRAM® Kit employs ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) to quantify 17 different GAGome disaccharides, which represent the most deregulated metabolites in cancer. This innovative approach not only aids in the early detection of multiple cancers but also serves as a monitoring and prognostic tool for specific cancer types, such as renal cell carcinoma and bladder cancer. Elypta's commitment to advancing cancer detection is further underscored by their recent clinical studies and recognition within the scientific community.

Sweden

Elypta is a Swedish molecular diagnostics company focused on reducing cancer mortality through early detection. Elypta is pioneering a metabolism-based liquid biopsy and measures the GAGome – system biomarkers of tumor metabolism. Machine learning algorithms are then used to detect signatures of cancer noninvasively. Elypta is advancing a broad clinical program across different cancers with the first indication expected to be early detection of recurrence in renal cell carcinoma.

Several years of research in Nielsen lab at Chalmers University of Technology in Gothenburg, Sweden led to the founding of Elypta in May 2017 by Francesco Gatto and Jens Nielsen.

Elypta

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