Intract Pharma is pioneering advancements in oral drug delivery technologies aimed at transforming patient care by replacing traditional injection methods with safer and more effective oral therapeutics. Their flagship technology, Soteria®, enables the administration of biopharmaceutical drugs, including monoclonal antibodies, in a convenient tablet or capsule form. This innovation is complemented by Phloral®, a dual-action technology designed for precise and consistent delivery of therapeutics to the colon. Phloral® utilizes changes in gastrointestinal pH and the enzymatic activity of the microbiota to ensure site-specific release, thereby enhancing bioavailability and overcoming the limitations of conventional drug delivery systems.

The company’s approach is further supported by their Dynamic Dissolution Model, which provides advanced in vitro testing to better predict how drugs will behave in the gastrointestinal tract. This model incorporates a unique bicarbonate-based media and a patented Auto pH System™ to simulate the dynamic conditions of the GI environment, allowing for more accurate assessments of drug solubility, stability, and permeability. By leveraging these innovative technologies, Intract Pharma aims to improve the efficacy and safety of both emerging and established protein therapeutics, ultimately enhancing patient experiences and outcomes in the treatment of inflammatory and immunological conditions.

United Kingdom

Intract Pharma is a biotechnology company innovating in the field of oral delivery of complex proteins such as monoclonal antibodies with a special focus on treatment of gastrointestinal and systemic immune-mediated inflammatory diseases. Intract is applying it’s Phloral™ and Soteria™ technology platform for precision delivery of proteins to the colon for local tissue and systemic immunomodulation. Our vision is to transform care for millions of patients suffering from chronic diseases by converting their potent injectable biologic medicines into safe, effective and convenient take-at-home pills.

Intract Pharma

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