AptamerLab specializes in the development and application of aptamers for medical diagnostics and therapy. Their comprehensive services encompass the entire aptamer lifecycle, from selection to three-dimensional structure determination. The company employs tailored selection tactics for each target, ensuring that the aptamers exhibit a sensitivity and specificity of at least 85%. Their methodologies include aptamer selection for various biological targets, such as whole cells, bacteria, and proteins, utilizing both in vitro and in vivo approaches. Additionally, they conduct mathematical analyses of sequenced aptamer pools to identify leading sequences and assess enrichment during the selection process.

The characterization of aptamers is another critical aspect of AptamerLab's offerings, where they evaluate the affinity, specificity, and dissociation constants using advanced techniques like flow cytometry and laser scanning microscopy. They also focus on defining the tertiary structure of aptamers through Small Angle X-ray Scattering, which aids in molecular design. Furthermore, AptamerLab employs the Aptamer-facilitated Biomarker Discovery technique combined with mass-spectrometry for protein target identification and verification. By utilizing clinical tissue samples, they ensure that the aptamers developed are effective and applicable to real-world medical challenges.

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Aptamerlab - Our Team Helps You Solve Medical Issues Using Working Aptamers

Aptamerlab

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